Related papers: Degree irregularity and rank probability bias in n…
Component network meta-analysis (CNMA) models are an extension of standard network meta-analysis (NMA) models which account for the use of multicomponent treatments in the network. This article contributes innovatively to several…
Background: Comparative effectiveness research using network meta-analysis can present a hierarchy of competing treatments, from the least to most preferable option. However, the research question associated with the hierarchy of multiple…
Network meta-analysis (NMA) of rare events has attracted little attention in the literature. Until recently, networks of interventions with rare events were analyzed using the inverse-variance NMA approach. However, when events are rare the…
Neural network models have become the leading solution for a large variety of tasks, such as classification, language processing, protein folding, and others. However, their reliability is heavily plagued by adversarial inputs: small input…
Network meta-analysis (NMA) combines direct and indirect comparisons across a connected treatment network to estimate relative treatment effects. However, there is a lack of exact contribution decompositions that reproduce NMA estimates,…
Asymmetry of in/out-degree distribution is a widespread phenomenon in real-world complex networks. This paper put forward the concept of Edge Asymmetry(EA) to quantify this feature. We designed an EA-based strategy to attack six kinds of…
Network meta-analysis (NMA) has been used to answer a range of clinical questions about the preferable intervention for a given condition. Although the effectiveness and safety of pharmacological agents depend on the dose administered, NMA…
Random-effects meta-analyses are very commonly used in medical statistics. Recent methodological developments include multivariate (multiple outcomes) and network (multiple treatments) meta-analysis. Here we provide a new model and…
Network alignment is a problem of finding the node mapping between similar networks. It links the data from separate sources and is widely studied in bioinformation and social network fields. The critical difference between network…
The reliability of the results of network meta-analysis (NMA) lies in the plausibility of key assumption of transitivity. This assumption implies that the effect modifiers' distribution is similar across treatment comparisons. Transitivity…
Network analysis provides powerful tools to learn about a variety of social systems. However, most analyses implicitly assume that the considered relational data is error-free, reliable and accurately reflects the system to be analysed.…
Real networks often have severe degree heterogeneity, with the maximum, average, and minimum node degrees differing significantly. This paper examines the impact of degree heterogeneity on statistical limits of network data analysis.…
While standard meta-analysis pools the results from randomized trials that compare two treatments, network meta-analysis aggregates the results of randomized trials comparing a wider variety of treatment options. However, it is unclear…
The surrounding of a vertex in a network can be more or less symmetric. We derive measures of a specific kind of symmetry of a vertex which we call degree symmetry -- the property that many paths going out from a vertex have overlapping…
Decisions based upon pairwise comparisons of multiple treatments are naturally performed in terms of the mean survival of the selected study arms or functions thereof. However, synthesis of treatment comparisons is usually performed on…
There has been a transition from broad to more specific research questions in the practice of network meta-analysis (NMA). Such convergence is also taking place in the context of individual registrational trials, following the recent…
Explicit modelling of between-study heterogeneity is essential in network meta-analysis (NMA) to ensure valid inference and avoid overstating precision. While the additive random-effects (RE) model is the conventional approach, the…
The stability of networks is greatly influenced by their degree distributions and in particular by their broadness. Networks with broader degree distributions are usually more robust to random failures but less robust to localized attacks.…
Dropout Regularization, serving to reduce variance, is nearly ubiquitous in Deep Learning models. We explore the relationship between the dropout rate and model complexity by training 2,000 neural networks configured with random…
This article discusses the properties of extremes of degree sequences calculated from network data. We introduce the notion of a normalized degree, in order to permit a comparison of degree sequences between networks with differing numbers…