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We develop factor copula models for analysing the dependence among mixed continuous and discrete responses. Factor copula models are canonical vine copulas that involve both observed and latent variables, hence they allow tail, asymmetric…

Methodology · Statistics 2020-11-18 Sayed H. Kadhem , Aristidis K. Nikoloulopoulos

Even though convolutional neural networks (CNNs) are driving progress in medical image segmentation, standard models still have some drawbacks. First, the use of multi-scale approaches, i.e., encoder-decoder architectures, leads to a…

Computer Vision and Pattern Recognition · Computer Science 2020-02-18 Ashish Sinha , Jose Dolz

We describe a robust, fast, and memory-efficient procedure that can cluster millions of structures derived from molecular dynamics simulations. The essence of the method is based on a peak-picking algorithm applied to three- and…

Biomolecules · Quantitative Biology 2015-12-15 Athanasios S. Baltzis , Panagiotis I. Koukos , Nicholas M. Glykos

Multi-view data are increasingly prevalent in practice. It is often relevant to analyze the relationships between pairs of views by multi-view component analysis techniques such as Canonical Correlation Analysis (CCA). However, data may…

Machine Learning · Statistics 2019-12-10 Eric Lei , Kyle Miller , Michael R. Pinsky , Artur Dubrawski

Composite development indicators used in policy making often subjectively aggregate a restricted set of indicators. We show, using dimensionality reduction techniques, including Principal Component Analysis (PCA) and for the first time…

General Economics · Economics 2020-03-27 Anshul Verma , Orazio Angelini , Tiziana Di Matteo

Multi-agent imitation learning aims to train multiple agents to perform tasks from demonstrations by learning a mapping between observations and actions, which is essential for understanding physical, social, and team-play systems. However,…

Machine Learning · Computer Science 2021-07-13 Hongwei Wang , Lantao Yu , Zhangjie Cao , Stefano Ermon

Integration of heterogeneous and high-dimensional multi-omics data is becoming increasingly important in understanding genetic data. Each omics technique only provides a limited view of the underlying biological process and integrating…

Machine Learning · Computer Science 2023-04-13 Chen Zhao , Anqi Liu , Xiao Zhang , Xuewei Cao , Zhengming Ding , Qiuying Sha , Hui Shen , Hong-Wen Deng , Weihua Zhou

Capturing complex dependence structures between outcome variables (e.g., study endpoints) is of high relevance in contemporary biomedical data problems and medical research. Distributional copula regression provides a flexible tool to model…

Methodology · Statistics 2022-02-28 Nicolai Hans , Nadja Klein , Florian Faschingbauer , Michael Schneider , Andreas Mayr

Molecular structures of RNA molecules reconstructed from X-ray crystallography frequently contain errors. Motivated by this problem we examine clustering on a torus since RNA shapes can be described by dihedral angles. A previously…

Biomolecules · Quantitative Biology 2021-04-02 Henrik Wiechers , Benjamin Eltzner , Stephan F. Huckemann , Kanti V. Mardia

For the analysis of clustered survival data, two different types of models that take the association into account, are commonly used: frailty models and copula models. Frailty models assume that conditional on a frailty term for each…

Methodology · Statistics 2014-01-10 Leen Prenen , Roel Braekers , Luc Duchateau

Genetic data are frequently categorical and have complex dependence structures that are not always well understood. For this reason, clustering and classification based on genetic data, while highly relevant, are challenging statistical…

Methodology · Statistics 2016-06-13 Gabriela Bettella Cybis , Marcio Valk , Silvia Regina Costa Lopes

Multi-view clustering has become a significant area of research, with numerous methods proposed over the past decades to enhance clustering accuracy. However, in many real-world applications, it is crucial to demonstrate a clear…

Machine Learning · Computer Science 2025-02-07 Mudi Jiang , Lianyu Hu , Zengyou He , Zhikui Chen

An extension of the latent class model is presented for clustering categorical data by relaxing the classical "class conditional independence assumption" of variables. This model consists in grouping the variables into inter-independent and…

Computation · Statistics 2015-10-01 Matthieu Marbac , Christophe Biernacki , Vincent Vandewalle

This paper proposes multivariate copula models for hierarchical data. They account for two types of correlation: one is between variables measured on the same unit and the other is a correlation between units in the same cluster. This model…

Methodology · Statistics 2023-04-24 Talagbe Gabin Akpo , Louis-Paul Rivest

A precise assessment of the risk of breast lesions can greatly lower it and assist physicians in choosing the best course of action. To categorise breast lesions, the majority of current computer-aided systems only use characteristics from…

Image and Video Processing · Electrical Eng. & Systems 2025-08-25 Muhaisin Tiyumba Nantogmah , Abdul-Barik Alhassan , Salamudeen Alhassan

Microbiome data analysis is essential for understanding host health and disease, yet its inherent sparsity and noise pose major challenges for accurate imputation, hindering downstream tasks such as biomarker discovery. Existing imputation…

Machine Learning · Computer Science 2025-08-01 Rabeya Tus Sadia , Qiang Cheng

Diverse applications - particularly in tumour subtyping - have demonstrated the importance of integrative clustering techniques for combining information from multiple data sources. Cluster-Of-Clusters Analysis (COCA) is one such approach…

Machine Learning · Statistics 2020-08-05 Alessandra Cabassi , Paul D. W. Kirk

Single-cell multi-view clustering enables the exploration of cellular heterogeneity within the same cell from different views. Despite the development of several multi-view clustering methods, two primary challenges persist. Firstly, most…

Genomics · Quantitative Biology 2023-11-30 Dayu Hu , Zhibin Dong , Ke Liang , Jun Wang , Siwei Wang , Xinwang Liu

With the advance of technology, entities can be observed in multiple views. Multiple views containing different types of features can be used for clustering. Although multi-view clustering has been successfully applied in many applications,…

Machine Learning · Computer Science 2016-04-20 Weixiang Shao , Jiawei Zhang , Lifang He , Philip S. Yu

While several Gaussian mixture models-based biclustering approaches currently exist in the literature for continuous data, approaches to handle discrete data have not been well researched. A multivariate Poisson-lognormal (MPLN) model-based…

Methodology · Statistics 2025-03-13 Caitlin Kral , Evan Chance , Ryan Browne , Sanjeena Subedi