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A common problem in genetics is that of testing whether a set of highly dependent gene expressions differ between two populations, typically in a high-dimensional setting where the data dimension is larger than the sample size. Most…

Methodology · Statistics 2015-03-11 Måns Thulin

We consider the hypothesis testing problem of detecting a shift between the means of two multivariate normal distributions in the high-dimensional setting, allowing for the data dimension p to exceed the sample size n. Specifically, we…

Statistics Theory · Mathematics 2015-09-15 Miles E. Lopes , Laurent J. Jacob , Martin J. Wainwright

Hotelling's T-squared test is a classical tool to test if the normal mean of a multivariate normal distribution is a specified one or the means of two multivariate normal means are equal. When the population dimension is higher than the…

Statistics Theory · Mathematics 2021-08-17 Tiefeng Jiang , Ping Li

It has been a long history in testing whether a mean vector with a fixed dimension has a specified value. Some well-known tests include the Hotelling $T^2$-test and the empirical likelihood ratio test proposed by Owen [Biometrika 75 (1988)…

Methodology · Statistics 2014-05-21 Liang Peng , Yongcheng Qi , Fang Wang

Power-enhanced tests with high-dimensional data have received growing attention in theoretical and applied statistics in recent years. Existing tests possess their respective high-power regions, and we may lack prior knowledge about the…

Methodology · Statistics 2021-10-01 Xiufan Yu , Danning Li , Lingzhou Xue , Runze Li

In this paper, we propose a novel approach to test the equality of high-dimensional mean vectors of several populations via the weighted $L_2$-norm. We establish the asymptotic normality of the test statistics under the null hypothesis. We…

Statistics Theory · Mathematics 2024-02-01 Jianghao Li , Zhenzhen Niu , Shizhe Hong , Zhidong Bai

We propose a likelihood ratio test framework for testing normal mean vectors in high-dimensional data under two common scenarios: the one-sample test and the two-sample test with equal covariance matrices. We derive the test statistics…

Methodology · Statistics 2018-09-25 Zongliang Hu , Tiejun Tong , Marc G. Genton

We consider testing for two-sample means of high dimensional populations by thresholding. Two tests are investigated, which are designed for better power performance when the two population mean vectors differ only in sparsely populated…

Methodology · Statistics 2014-10-13 Song Xi Chen , Jun Li , Ping-Shou Zhong

For high-dimensional small sample size data, Hotelling's T2 test is not applicable for testing mean vectors due to the singularity problem in the sample covariance matrix. To overcome the problem, there are three main approaches in the…

Methodology · Statistics 2020-03-11 Zongliang Hu , Tiejun Tong , Marc G. Genton

We propose a method of testing the shift between mean vectors of two multivariate Gaussian random variables in a high-dimensional setting incorporating the possible dependency and allowing $p > n$. This method is a combination of two…

Methodology · Statistics 2019-12-24 Tzviel Frostig , Yoav Benjamini

Most existing methods for testing equality of means of functional data from multiple populations rely on assumptions of equal covariance and/or Gaussianity. In this work we provide a new testing method based on a statistic that is…

Methodology · Statistics 2025-09-30 Chuang Xu , Andrew T. A. Wood , Yanrong Yang

Testing differences in mean vectors is a fundamental task in the analysis of high-dimensional compositional data. Existing methods may suffer from low power if the underlying signal pattern is in a situation that does not favor the deployed…

Methodology · Statistics 2025-03-11 Danning Li , Lingzhou Xue , Haoyi Yang , Xiufan Yu

Motivated by the likelihood ratio test under the Gaussian assumption, we develop a maximum sum-of-squares test for conducting hypothesis testing on high dimensional mean vector. The proposed test which incorporates the dependence among the…

Methodology · Statistics 2015-10-21 Xianyang Zhang

We propose a two-sample mean test based on the Bayes factor with non-informative priors, specifically designed for scenarios where the dimension $p$ grows with the sample size $n$ with a linear rate $p/n \to c_1 \in (0, \infty)$. We…

Methodology · Statistics 2026-04-07 Daojiang He , Suren Xu , Jing Zhou

We propose two tests for the equality of covariance matrices between two high-dimensional populations. One test is on the whole variance--covariance matrices, and the other is on off-diagonal sub-matrices, which define the covariance…

Statistics Theory · Mathematics 2012-06-06 Jun Li , Song Xi Chen

We propose novel methodology for testing equality of model parameters between two high-dimensional populations. The technique is very general and applicable to a wide range of models. The method is based on sample splitting: the data is…

Methodology · Statistics 2013-01-17 Nicolas Städler , Sach Mukherjee

In high dimensions, the classical Hotelling's $T^2$ test tends to have low power or becomes undefined due to singularity of the sample covariance matrix. In this paper, this problem is overcome by projecting the data matrix onto lower…

Methodology · Statistics 2014-05-09 Radhendushka Srivastava , Ping Li , David Ruppert

In this paper, we propose a new test for testing the equality of two population covariance matrices in the ultra-high dimensional setting that the dimension is much larger than the sizes of both of the two samples. Our proposed methodology…

Methodology · Statistics 2023-12-19 Xiucai Ding , Yichen Hu , Zhenggang Wang

Testing the equality of the covariance matrices of two high-dimensional samples is a fundamental inference problem in statistics. Several tests have been proposed but they are either too liberal or too conservative when the required…

Statistics Theory · Mathematics 2023-01-04 Jin-Ting Zhang , Jingyi Wang , Tianming Zhu

We propose optimal Bayesian two-sample tests for testing equality of high-dimensional mean vectors and covariance matrices between two populations. In many applications including genomics and medical imaging, it is natural to assume that…

Methodology · Statistics 2021-12-07 Kyoungjae Lee , Kisung You , Lizhen Lin
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