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Cell division and death can be regulated by the mechanical forces within a tissue. We study the consequences for the stability and roughness of a propagating interface, by analysing a model of mechanically-regulated tissue growth in the…

Biological Physics · Physics 2018-12-12 John J. Williamson , Guillaume Salbreux

Mechanical forces influence the dynamics of growing tissues. Computer simulations are employed to study the importance of interfacial effects in tissue competition. It was speculated that mechanical pressure determines the competition,…

Biological Physics · Physics 2024-06-03 Nirmalendu Ganai , Tobias Buscher , Gerhard Gompper , Jens Elgeti

During the spreading of epithelial tissues, the advancing tissue front often develops fingerlike protrusions. Their resemblance to traditional viscous fingering patterns in driven fluids suggests that epithelial fingers could arise from an…

Biological Physics · Physics 2019-03-05 Ricard Alert , Carles Blanch-Mercader , Jaume Casademunt

Motivated by studies suggesting that the patterns exhibited by the collectively expanding fronts of thin cells during the closing of a wound [Mark et al., Biophys. J., 98:361-370, 2010] and the shapes of single cells crawling on surfaces…

Soft Condensed Matter · Physics 2018-03-14 Amarender Nagilla , Ranganathan Prabhakar , Sameer Jadhav

The stability of the boundary between regenerating tissues is essential to the maintenance of their integrity and biological function. Stress is known to play an important role in the regulation of cell division, cell growth and cell death,…

Biological Physics · Physics 2024-11-20 Luis Gómez-Nava , Djamel Chekroun , Ioan Ionescu , Marc Durand

When a liquid viscous bridge between two parallel substrates is stretched by accelerating one substrate, its interface recedes in the radial direction. In some cases the interface becomes unstable. Such instability leads to the emergence of…

Fluid Dynamics · Physics 2019-12-05 Sebastian Brulin , Ilia V. Roisman , Cameron Tropea

The invasion of one fluid into another of higher viscosity in a quasi-two dimensional geometry typically produces complex fingering patterns. Because interfacial tension suppresses short-wavelength fluctuations, its elimination by using…

Fluid Dynamics · Physics 2015-06-23 Irmgard Bischofberger , Radha Ramachandran , Sidney R. Nagel

The dynamics of sharp interfaces separating two non-hydrostatically stressed solids is analyzed using the idea that the rate of mass transport across the interface is proportional to the thermodynamic potential difference across the…

Materials Science · Physics 2009-11-13 Luiza Angheluta , Espen Jettestuen , Joachim Mathiesen

Interfaces between stratified epithelia and their supporting stromas commonly exhibit irregular shapes. Undulations are particularly pronounced in dysplastic tissues and typically evolve into long, finger-like protrusions in carcinomas. In…

Biological Physics · Physics 2013-06-25 Thomas Risler , Markus Basan

We investigate some unstable behavior of the interface given by two incompressible fluids of different densities evolving by the regular Stokes law with gravity force. In the unstable scenario, where the denser fluid lies above the lighter…

Analysis of PDEs · Mathematics 2026-01-27 Francisco Gancedo , Rafael Granero-Belinchón , Zhongtian Hu , Elena Salguero , Yao Yao

The viscous fingering instability, which forms when a less-viscous fluid invades a more-viscous one within a confined geometry, is an iconic system for studying pattern formation. For both miscible and immiscible fluid pairs the growth…

Fluid Dynamics · Physics 2025-02-25 Savannah D. Gowen , Thomas E. Videbaek , Sidney R. Nagel

We study the dynamical behavior of a one dimensional interface interacting with a sticky unpenetrable substrate or wall. The interface is subject to two effects going in opposite directions. Contact between the interface and the substrate…

Probability · Mathematics 2020-07-20 Hubert Lacoin , Shangjie Yang

The shock wave instability induced when interacting with a small waviness on an interface was investigated analytically and numerically. The perturbation to the shock was phenomenologically treated assuming this as the consequence of the…

Fluid Dynamics · Physics 2018-08-29 A. Markhotok

This work focuses on the interfacial dynamics with interfacial mass flux in the presence of acceleration and surface tension. We employ the general matrix method to find the fundamental solutions for the linearized boundary value problem…

Fluid Dynamics · Physics 2021-07-07 D. V. Ilyin , S. I. Abarzhi

The Rayleigh capillary instability of a cylindrical interface between two immiscible fluids is one of the most fundamental in fluid dynamics. As Plateau observed from energetic considerations and Rayleigh clarified through hydrodynamics,…

Soft Condensed Matter · Physics 2009-10-30 Thomas R. Powers , Dengfu Zhang , Raymond E. Goldstein , Howard A. Stone

When a spatially localized stress is applied to a growing one-dimensional interface, the interface deforms. This deformation is described by the effective surface tension representing the stiffness of the interface. We present that the…

Statistical Mechanics · Physics 2023-05-17 Mutsumi Minoguchi , Shin-ichi Sasa

We present a theoretical and numerical study on the (in)stability of the interface between two immiscible liquids, i.e., viscous fingering, in angled Hele-Shaw cells across a range of capillary numbers ($Ca$). We consider two types of…

Fluid Dynamics · Physics 2020-03-06 Daihui Lu , Federico Municchi , Ivan C. Christov

We demonstrate that topological insulators exhibit an intrinsic interfacial instability that amplifies small interface fluctuations, resulting in chaotic behavior during interface growth. This mechanism is fundamentally different from…

Mesoscale and Nanoscale Physics · Physics 2025-12-29 Yutaro Tanaka , Akira Furusaki

In many adult tissues, stem cells and differentiated cells are not homogeneously distributed : stem cells are arranged in periodic "niches", and differentiated cells are constantly produced and migrate out of these niches. In this article,…

Biological Physics · Physics 2016-03-23 Edouard Hannezo , Alice Coucke , Jean-François Joanny

We develop a computational method for simulating the nonlinear dynamics of an elastic tumor-host interface. This work is motivated by the recent linear stability analysis of a two-phase tumor model with an elastic membrane interface in 2D.…

Numerical Analysis · Mathematics 2019-12-12 Min-Jhe Lu , Chun Liu , Shuwang Li
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