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We develop a model-based methodology for integrating gene-set information with an experimentally-derived gene list. The methodology uses a previously reported sampling model, but takes advantage of natural constraints in the…

Methodology · Statistics 2015-06-02 Zhishi Wang , Qiuling He , Bret Larget , Michael A. Newton

Large pre-trained vision-language models (VLMs), such as CLIP, demonstrate impressive generalization but remain highly vulnerable to adversarial examples (AEs). Previous work has explored robust text prompts through adversarial training,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Xiaojun Jia , Sensen Gao , Simeng Qin , Ke Ma , Xinfeng Li , Yihao Huang , Wei Dong , Yang Liu , Xiaochun Cao

This paper introduces a prognostic method called FLASH that addresses the problem of joint modelling of longitudinal data and censored durations when a large number of both longitudinal and time-independent features are available. In the…

Analyzing data from multiple sources offers valuable opportunities to improve the estimation efficiency of causal estimands. However, this analysis also poses many challenges due to population heterogeneity and data privacy constraints.…

Methodology · Statistics 2025-10-23 Rong Zhao , Jason Falvey , Xu Shi , Vernon M. Chinchilli , Chixiang Chen

Federated learning (FL) is a privacy-preserving distributed management framework based on collaborative model training of distributed devices in edge networks. However, recent studies have shown that FL is vulnerable to adversarial examples…

Computer Vision and Pattern Recognition · Computer Science 2024-03-06 Yu Qiao , Apurba Adhikary , Chaoning Zhang , Choong Seon Hong

Genetic interaction measures how different genes collectively contribute to a phenotype, and can reveal functional compensation and buffering between pathways under genetic perturbations. Recently, genome-wide screening for genetic…

Molecular Networks · Quantitative Biology 2015-03-17 Gang Fang , Wen Wang , Vanja Paunic , Benjamin Oately , Majda Haznadar , Michael Steinbach , Brian Van Ness , Chad L. Myers , Vipin Kumar

The main objective of accelerated life tests (ALTs) is to predict fraction failings of products in the field. However, there are often discrepancies between the predicted fraction failing from the lab testing data and that from the field…

Applications · Statistics 2014-01-13 Zhi-Sheng Ye , Yili Hong , Yimeng Xie

In recent times, many of the breakthroughs in various vision-related tasks have revolved around improving learning of deep models; these methods have ranged from network architectural improvements such as Residual Networks, to various forms…

Machine Learning · Statistics 2018-05-15 Yan Zuo , Gil Avraham , Tom Drummond

Kernel-based multi-marker tests for survival outcomes use primarily the Cox model to adjust for covariates. The proportional hazards assumption made by the Cox model could be unrealistic, especially in the long-term follow-up. We develop a…

Methodology · Statistics 2024-01-19 Chenxi Li , Di Wu , Qing Lu

In studies of time-to-event outcomes with unmeasured heterogeneity, the hazard ratio for treatment is known to have a complex causal interpretation. Accelerated failure time (AFT) models, which assess the effect on the survival time ratio…

Methodology · Statistics 2026-03-18 Mari Brathovde , Hein Putter , Morten Valberg , Richard A. J. Post

There is growing interest in exploring causal effects in target populations via data combination. However, most approaches are tailored to specific settings and lack comprehensive comparative analyses. In this article, we focus on a typical…

Methodology · Statistics 2024-09-17 Peng Wu , Shanshan Luo , Zhi Geng

Accelerated life-tests (ALTs) are used for inferring lifetime characteristics of highly reliable products. In particular, step-stress ALTs increase the stress level at which units under test are subject at certain pre-fixed times, thus…

Statistics Theory · Mathematics 2024-02-12 Narayanaswamy Balakrishnan , Maria Jaenada , Leandro Pardo

Generative adversarial nets (GANs) have become a preferred tool for tasks involving complicated distributions. To stabilise the training and reduce the mode collapse of GANs, one of their main variants employs the integral probability…

Machine Learning · Computer Science 2020-10-27 Shengxi Li , Zeyang Yu , Min Xiang , Danilo Mandic

Concurrent multiscale damage models are often used to quantify the impacts of manufacturing-induced micro porosity on the damage response of macroscopic metallic components. However, these models are challenged by major numerical issues…

Computational Engineering, Finance, and Science · Computer Science 2023-02-21 Shiguang Deng , Diran Apelian , Ramin Bostanabad

In this paper, we study the generative models of sequential discrete data. To tackle the exposure bias problem inherent in maximum likelihood estimation (MLE), generative adversarial networks (GANs) are introduced to penalize the…

Machine Learning · Computer Science 2019-05-14 Sidi Lu , Lantao Yu , Siyuan Feng , Yaoming Zhu , Weinan Zhang , Yong Yu

Recent studies have proven that deep neural networks are vulnerable to backdoor attacks. Specifically, by mixing a small number of poisoned samples into the training set, the behavior of the trained model can be maliciously controlled.…

Computer Vision and Pattern Recognition · Computer Science 2022-06-07 Pengfei Xia , Ziqiang Li , Wei Zhang , Bin Li

Matching has become the mainstream in counterfactual inference, with which selection bias between sample groups can be significantly eliminated. However in practice, when estimating average treatment effect on the treated (ATT) via…

Econometrics · Economics 2022-06-14 Boyang You , Kerry Papps

Learning features from data is one of the defining characteristics of deep learning, but our theoretical understanding of the role features play in deep learning is still rudimentary. To address this gap, we introduce a new tool, the…

Machine Learning · Computer Science 2023-06-09 Yiding Jiang , Christina Baek , J. Zico Kolter

Generative Adversarial Networks (GANs) should produce synthetic data that fits the underlying distribution of the data being modeled. For real valued time-series data, this implies the need to simultaneously capture the static distribution…

Machine Learning · Computer Science 2024-05-14 Joe Beck , Subhadeep Chakraborty

A population-averaged additive subdistribution hazards model is proposed to assess the marginal effects of covariates on the cumulative incidence function and to analyze correlated failure time data subject to competing risks. This approach…

Methodology · Statistics 2023-08-23 Xinyuan Chen , Denise Esserman , Fan Li