Related papers: The case for algebraic biology: from research to e…
This paper focuses on polynomial dynamical systems over finite fields. These systems appear in a variety of contexts, in computer science, engineering, and computational biology, for instance as models of intracellular biochemical networks.…
Rearrangements of bacterial chromosomes can be studied mathematically at several levels, most prominently at a local, or sequence level, as well as at a topological level. The biological changes involved locally are inversions, deletions,…
In this position paper, we promote the study of function spaces parameterized by machine learning models through the lens of algebraic geometry. To this end, we focus on algebraic models, such as neural networks with polynomial activations,…
The algebraic structure, linear algebra happens to be one of the subjects which yields itself to applications to several fields like coding or communication theory, Markov chains, representation of groups and graphs, Leontief economic…
We showcase applications of nonlinear algebra in the sciences and engineering. Our review is organized into eight themes: polynomial optimization, partial differential equations, algebraic statistics, integrable systems, configuration…
In the last quarter of a century, algebraic statistics has established itself as an expanding field which uses multilinear algebra, commutative algebra, computational algebra, geometry, and combinatorics to tackle problems in mathematical…
The grand challenges in biology today are being shaped by powerful high-throughput technologies that have revealed the genomes of many organisms, global expression patterns of genes and detailed information about variation within…
Linear algebra represents, with calculus, the two main mathematical subjects taught in science universities. However this teaching has always been difficult. In the last two decades, it became an active area for research works in…
Researchers working with mathematical models are often confronted by the related problems of parameter estimation, model validation, and model selection. These are all optimization problems, well-known to be challenging due to…
The relationship between algebraic geometry and the inferential framework of the Bayesian Networks with hidden variables has now been fruitfully explored and exploited by a number of authors. More recently the algebraic formulation of…
Biology is data-rich, and it is equally rich in concepts and hypotheses. Part of trying to understand biological processes and systems is therefore to confront our ideas and hypotheses with data using statistical methods to determine the…
Efficient numerical linear algebra is a core ingredient in many applications across almost all scientific and industrial disciplines. With this survey we want to illustrate that numerical linear algebra has played and is playing a crucial…
These are the notes of my lectures at the 1996 European Congress of Mathematicians. {} Polynomials appear in mathematics frequently, and we all know from experience that low degree polynomials are easier to deal with than high degree ones.…
Biomedical networks (or graphs) are universal descriptors for systems of interacting elements, from molecular interactions and disease co-morbidity to healthcare systems and scientific knowledge. Advances in artificial intelligence,…
Although algebraic matroids were discovered in the 1930s, interest in them was largely dormant until their recent use in applications of algebraic geometry. Because nonlinear algebra is computationally challenging, it is easier to work with…
Network biology is an interdisciplinary field bridging computational and biological sciences that has proved pivotal in advancing the understanding of cellular functions and diseases across biological systems and scales. Although the field…
Polynomial algebra offers a standard approach to handle several problems in geometric modeling. A key tool is the discriminant of a univariate polynomial, or of a well-constrained system of polynomial equations, which expresses the…
We develop the necessary theory in computational algebraic geometry to place Bayesian networks into the realm of algebraic statistics. We present an algebra{statistics dictionary focused on statistical modeling. In particular, we link the…
Steady state analysis of dynamical systems for biological networks give rise to algebraic varieties in high-dimensional spaces whose study is of interest in their own right. We demonstrate this for the shuttle model of the Wnt signaling…
This work connects two mathematical fields - computational complexity and interval linear algebra. It introduces the basic topics of interval linear algebra - regularity and singularity, full column rank, solving a linear system, deciding…