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In this paper, we introduce an end-to-end machine learning-based system for classifying autism spectrum disorder (ASD) using facial attributes such as expressions, action units, arousal, and valence. Our system classifies ASD using…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Beibin Li , Sachin Mehta , Deepali Aneja , Claire Foster , Pamela Ventola , Frederick Shic , Linda Shapiro

Autism spectrum disorder (ASD) affects the brain connectivity at different levels. Nonetheless, non-invasively distinguishing such effects using magnetic resonance imaging (MRI) remains very challenging to machine learning diagnostic…

Machine Learning · Computer Science 2020-04-29 Ismail Bilgen , Goktug Guvercin , Islem Rekik

Structural magnetic resonance imaging (sMRI) can identify subtle brain changes due to its high contrast for soft tissues and high spatial resolution. It has been widely used in diagnosing neurological brain diseases, such as Alzheimer…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Xin Zhang , Liangxiu Han , Lianghao Han , Haoming Chen , Darren Dancey , Daoqiang Zhang

Since the strong comorbid similarity in NDDs, such as attention-deficit hyperactivity disorder, can interfere with the accurate diagnosis of autism spectrum disorder (ASD), identifying unknown classes is extremely crucial and challenging…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Jiaming Yu , Zihao Guan , Xinyue Chang , Shujie Liu , Zhenshan Shi , Xiumei Liu , Changcai Yang , Riqing Chen , Lanyan Xue , Lifang Wei

Autism spectrum disorder is one of the leading neurodevelopmental disorders in our world, present in over 1% of the population and rapidly increasing in prevalence, yet the condition lacks a robust, objective, and efficient diagnostic.…

Neurons and Cognition · Quantitative Biology 2024-03-04 Annie Adhikary

Resting-state fMRI is commonly used for diagnosing Autism Spectrum Disorder (ASD) by using network-based functional connectivity. It has been shown that ASD is associated with brain regions and their inter-connections. However,…

Neurons and Cognition · Quantitative Biology 2022-01-04 Ranjeet Ranjan Jha , Abhishek Bhardwaj , Devin Garg , Arnav Bhavsar , Aditya Nigam

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition that encompasses a wide variety of symptoms and degrees of impairment, which makes the diagnosis and treatment challenging. Functional magnetic resonance imaging (fMRI) has…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Yinchi Zhou , Peiyu Duan , Yuexi Du , Nicha C. Dvornek

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition marked by disruptions in brain connectivity. Functional MRI (fMRI) offers a non-invasive window into large-scale neural dynamics by measuring…

Machine Learning · Computer Science 2025-08-20 Mohammad Izadi , Mehran Safayani

Current neuroimaging techniques provide paths to investigate the structure and function of the brain in vivo and have made great advances in understanding Alzheimer's disease (AD). However, the group-level analyses prevalently used for…

Quantitative Methods · Quantitative Biology 2021-05-31 Nanyan Zhu , Chen Liu , Xinyang Feng , Dipika Sikka , Sabrina Gjerswold-Selleck , Scott A. Small , Jia Guo

Autism spectrum disorder (ASD) is a neurodevelopmental disorder which results in altered behavior, social development, and communication patterns. In past years, autism prevalence has tripled, with 1 in 54 children now affected. Given that…

A common neurodegenerative disease, Alzheimer's disease requires a precise diagnosis and efficient treatment, particularly in light of escalating healthcare expenses and the expanding use of artificial intelligence in medical diagnostics.…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Soyabul Islam Lincoln , Mirza Mohd Shahriar Maswood

Increasing the volume of training data can enable the auxiliary diagnostic algorithms for Autism Spectrum Disorder (ASD) to learn more accurate and stable models. However, due to the significant heterogeneity and domain shift in rs-fMRI…

Neurons and Cognition · Quantitative Biology 2025-07-11 Yiqian Luo , Qiurong Chen , Fali Li , Peng Xu , Yangsong Zhang

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by varied social cognitive challenges and repetitive behavioral patterns. Identifying reliable brain imaging-based biomarkers for ASD has been a persistent…

Machine Learning · Computer Science 2024-09-30 Mehul Arora , Chirag Shantilal Jain , Lalith Bharadwaj Baru , Kamalaker Dadi , Bapi Raju Surampudi

Current models on Explainable Artificial Intelligence (XAI) have shown an evident and quantified lack of reliability for measuring feature-relevance when statistically entangled features are proposed for training deep classifiers. There has…

Signal Processing · Electrical Eng. & Systems 2023-02-27 Juan Manuel Mayor-Torres , Sara Medina-DeVilliers , Tessa Clarkson , Matthew D. Lerner , Giuseppe Riccardi

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by atypical brain connectivity. One of the crucial steps in addressing ASD is its early detection. This study introduces a novel computational framework that…

Applications · Statistics 2026-03-31 Abigail Kelly , Ramchandra Rimal , Arpan Sainju

Currently, the diagnosis of Autism Spectrum Disorder (ASD) is dependent upon a subjective, time-consuming evaluation of behavioral tests by an expert clinician. Non-invasive functional MRI (fMRI) characterizes brain connectivity and may be…

Machine Learning · Computer Science 2020-05-26 Cooper J. Mellema , Alex Treacher , Kevin P. Nguyen , Albert Montillo

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that predominantly affects the elderly population and currently has no cure. Magnetic Resonance Imaging (MRI), as a non-invasive imaging technique, is essential for the…

Image and Video Processing · Electrical Eng. & Systems 2025-07-24 Xinyue Yang , Meiliang Liu , Yunfang Xu , Xiaoxiao Yang , Zhengye Si , Zijin Li , Zhiwen Zhao

Conventionally, evaluation for the diagnosis of Autism spectrum disorder is done by a trained specialist through questionnaire-based formal assessments and by observation of behavioral cues under various settings to capture the early…

Computer Vision and Pattern Recognition · Computer Science 2023-11-28 Vaibhavi Lokegaonkar , Vijay Jaisankar , Pon Deepika , Madhav Rao , T K Srikanth , Sarbani Mallick , Manjit Sodhi

Early diagnosis of Autism Spectrum Disorder (ASD) is an effective and favorable step towards enhancing the health and well-being of children with ASD. Manual ASD diagnosis testing is labor-intensive, complex, and prone to human error due to…

Artificial Intelligence · Computer Science 2024-09-30 Chinthaka Ranasingha , Harshala Gammulle , Tharindu Fernando , Sridha Sridharan , Clinton Fookes

Autism Spectrum Disorders are associated with atypical movements, of which stereotypical motor movements (SMMs) interfere with learning and social interaction. The automatic SMM detection using inertial measurement units (IMU) remains…

Computer Vision and Pattern Recognition · Computer Science 2017-09-19 Nastaran Mohammadian Rad , Seyed Mostafa Kia , Calogero Zarbo , Twan van Laarhoven , Giuseppe Jurman , Paola Venuti , Elena Marchiori , Cesare Furlanello