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The human electroencephalogram (EEG) of sleep undergoes profound changes with age. These changes can be conceptualized as "brain age", which can be compared to an age norm to reflect the deviation from normal aging process. Here, we develop…

The determination of biological brain age is a crucial biomarker in the assessment of neurological disorders and understanding of the morphological changes that occur during aging. Various machine learning models have been proposed for…

Image and Video Processing · Electrical Eng. & Systems 2023-06-12 Mansoor Ahmed , Usama Sardar , Sarwan Ali , Shafiq Alam , Murray Patterson , Imdad Ullah Khan

The brain's biological age has been considered as a promising candidate for a neurologically significant biomarker. However, recent results based on longitudinal magnetic resonance imaging data have raised questions on its interpretation. A…

Neurons and Cognition · Quantitative Biology 2023-10-12 Lukas AW Gemein , Robin T Schirrmeister , Joschka Boedecker , Tonio Ball

Preterm newborns undergo various stresses that may materialize as learning problems at school-age. Sleep staging of the Electroencephalogram (EEG), followed by prediction of their brain-age from these sleep states can quantify deviations…

Machine Learning · Statistics 2018-09-20 Kirubin Pillay , Maarten De Vos

The extent of intra-individual and inter-individual variability is an important factor in determining the statistical, and hence possibly clinical, significance of observed differences in the EEG. This study investigates the changes in…

Neurons and Cognition · Quantitative Biology 2018-01-08 Sacha Jennifer van Albada , Christopher J. Rennie , Peter A. Robinson

Electroencephalography (EEG)-based wearable brain-computer interfaces (BCIs) face challenges due to low signal-to-noise ratio (SNR) and non-stationary neural activity. We introduce in this manuscript a mathematically rigorous framework that…

Neurons and Cognition · Quantitative Biology 2025-09-24 Eva Guttmann-Flury , Shan Zhao , Jian Zhao , Mohamad Sawan

Electroencephalography (EEG) underpins neuroscience, clinical neurophysiology, and brain-computer interfaces (BCIs), yet pronounced inter- and intra-subject variability limits reliability, reproducibility, and translation. This systematic…

Neurons and Cognition · Quantitative Biology 2026-02-03 Xuan-The Tran , Thien-Nhan Vo , Son-Tung Vu , Thoa-Thi Tran , Manh-Dat Nguyen , Thomas Do , Chin-Teng Lin

The concept of biological age (BA), although important in clinical practice, is hard to grasp mainly due to the lack of a clearly defined reference standard. For specific applications, especially in pediatrics, medical image data are used…

Image and Video Processing · Electrical Eng. & Systems 2021-03-22 Karim Armanious , Sherif Abdulatif , Wenbin Shi , Shashank Salian , Thomas Küstner , Daniel Weiskopf , Tobias Hepp , Sergios Gatidis , Bin Yang

Electroencephalography (EEG) is a method to record the electrical signals in the brain. Recognizing the EEG patterns in the sleeping brain gives insights into the understanding of sleeping disorders. The dataset under consideration contains…

Machine Learning · Statistics 2018-04-25 Aditya Chindhade , Abhijeet Alshi , Aakash Bhatia , Kedar Dabhadkar , Pranav Sivadas Menon

In this paper, electroencephalography (EEG) measurements are used to infer change in cortical functional connectivity in response to change in audio stimulus. Experiments are conducted wherein the EEG activity of human subjects is recorded…

Signal Processing · Electrical Eng. & Systems 2018-02-20 Ketan Mehta , Joerg Kliewer

In this study we investigate a textural processing method of electroencephalography (EEG) signal as an indicator to estimate the driver's vigilance in a hypothetical Brain-Computer Interface (BCI) system. The novelty of the solution…

Computer Vision and Pattern Recognition · Computer Science 2020-10-20 Giulia Orrù , Marco Micheletto , Fabio Terranova , Gian Luca Marcialis

Brain-computer interfaces (BCIs) often suffer from limited robustness and poor long-term adaptability. Model performance rapidly degrades when user attention fluctuates, brain states shift over time, or irregular artifacts appear during…

Signal Processing · Electrical Eng. & Systems 2025-11-12 Yeon-Woo Choi , Hye-Bin Shin , Dan Li

Numerous studies have established that estimated brain age, as derived from statistical models trained on healthy populations, constitutes a valuable biomarker that is predictive of cognitive decline and various neurological diseases. In…

Computer Vision and Pattern Recognition · Computer Science 2019-07-02 Xinyang Feng , Zachary C. Lipton , Jie Yang , Scott A. Small , Frank A. Provenzano

In this work, we leverage machine learning techniques to identify potential biomarkers of oxygen desaturation during sleep exclusively from electroencephalogram (EEG) signals in pediatric patients with sleep apnea. Development of a machine…

Signal Processing · Electrical Eng. & Systems 2025-02-03 Shashank Manjunath , Aarti Sathyanarayana

Sleep is vital for people's physical and mental health, and sound sleep can help them focus on daily activities. Therefore, a sleep study that includes sleep patterns and sleep disorders is crucial to enhancing our knowledge about…

Machine Learning · Computer Science 2025-04-18 Tayab Uddin Wara , Ababil Hossain Fahad , Adri Shankar Das , Md. Mehedi Hasan Shawon

Diagnosing sleep disorders is an important focus in neuroscience and engineering, as these conditions involve issues such as insufficient sleep, frequent awakenings, and difficulty reaching deep sleep. Accurate detection based on brain…

Neurons and Cognition · Quantitative Biology 2025-09-03 Mohammad Reza Yousefi , Reza Rahimi

Over recent decades, neuroimaging tools, particularly electroencephalography (EEG), have revolutionized our understanding of the brain and its functions. EEG is extensively used in traditional brain-computer interface (BCI) systems due to…

Neurons and Cognition · Quantitative Biology 2026-05-12 Zaineb Ajra , Binbin Xu , Gérard Dray , Jacky Montmain , Stéphane Perrey

The brain age is a key indicator of brain health. While electroencephalography (EEG) is a practical tool for this task, existing models struggle with the common challenge of imperfect medical data, such as learning a ``normal'' baseline…

Machine Learning · Computer Science 2025-11-25 Kunyu Zhang , Mingxuan Wang , Xiangjie Shi , Haoxing Xu , Chao Zhang

A brain-computer interface (BCI) establishes a direct communication pathway between the brain and an external device. Electroencephalogram (EEG) is the most popular input signal in BCIs, due to its convenience and low cost. Most research on…

Human-Computer Interaction · Computer Science 2024-12-16 L. Meng , X. Jiang , J. Huang , W. Li , H. Luo , D. Wu

This study investigates the sleep characteristics and brain activity of individuals in the gray zone of insomnia, a population that experiences sleep disturbances yet does not fully meet the clinical criteria for chronic insomnia. Thirteen…

Human-Computer Interaction · Computer Science 2024-11-18 Ha-Na Jo , Young-Seok Kweon , Seo-Hyun Lee
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