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We discuss the emergence and growth of the cooperativity accompanying vitrification based on the density fluctuation dynamics for fragile glass-forming liquids. (i) The relaxation of density fluctuations proceeds by the particle (density)…

Soft Condensed Matter · Physics 2019-11-11 Akira Furukawa

To maintain homeostasis, living cells process information with networks of interacting molecules. Traditional models for cellular information processing have focused on networks of chemical reactions between molecules. Here, we describe how…

Biological Physics · Physics 2025-08-01 Arvind Murugan , David Zwicker , Charlotta Lorenz , Eric R. Dufresne

Swap algorithms can shift the glass transition to lower temperatures, a recent unexplained observation constraining the nature of this phenomenon. Here we show that swap dynamic is governed by an effective potential describing both particle…

Soft Condensed Matter · Physics 2018-09-12 Carolina Brito , Edan Lerner , Matthieu Wyart

Aspects of the dynamical glass transition are considered within a mean field spin glass model. At the dynamical transition the the system condenses in a state of lower entropy. The difference, the information entropy or complexity, is…

Condensed Matter · Physics 2007-05-23 Th. M. Nieuwenhuizen

Glassy dynamics in active biological cells remain a subject of debate, as cellular activity rarely slows enough for true glassy features to emerge. In this study, we address this paradox of glassy dynamics in epithelial cells by integrating…

The interplay between cytoskeletal architecture and the nonlinearity of the interactions due to bucklable filaments plays a key role in modulating the cell's mechanical stability and affecting its structural rearrangements. We study a model…

Statistical Mechanics · Physics 2011-07-01 Shenshen Wang , Tongye Shen , Peter G. Wolynes

Diverse processes--e.g. bioremediation, biofertilization, and microbial drug delivery--rely on bacterial migration in disordered, three-dimensional (3D) porous media. However, how pore-scale confinement alters bacterial motility is unknown…

Soft Condensed Matter · Physics 2019-05-09 Tapomoy Bhattacharjee , Sujit S. Datta

An equilibrated model glass-forming liquid is studied by mapping successive configurations produced by molecular dynamics simulation onto a time series of inherent structures (local minima in the potential energy). Using this ``inherent…

Soft Condensed Matter · Physics 2012-03-27 Thomas B. Schroeder , Srikanth Sastry , Jeppe C. Dyre , Sharon C. Glotzer

The structural arrest of a polymeric suspension might be driven by an increase of the cross--linker concentration, that drives the gel transition, as well as by an increase of the polymer density, that induces a glass transition. These…

Statistical Mechanics · Physics 2014-06-20 Nagi Khalil , Antonio Coniglio , Antonio de Candia , Annalisa Fierro , Massimo Pica Ciamarra

We investigate how structural relaxation in mixtures with strong dynamical asymmetry is affected by the microscopic dynamics. Brownian and Newtonian dynamics simulations of dense mixtures of fast and slow hard spheres reveal a striking…

Soft Condensed Matter · Physics 2017-10-02 Suvendu Mandal , Thomas Franosch , Thomas Voigtmann

The physics of highly excited Rydberg atoms is governed by blockade or exclusion interactions that hinder the excitation of atoms in the proximity of a previously excited one. This leads to cooperative effects and a relaxation dynamics…

Statistical Mechanics · Physics 2018-09-12 Carlos Pérez-Espigares , Igor Lesanovsky , Juan P. Garrahan , Ricardo Gutiérrez

Transmembrane water permeability, which regulates cellular water exchange and is influenced by water channels such as aquaporin-4 (AQP4), has been implicated in glioma progression and may affect tumour infiltration and treatment response.…

Dynamic facilitation theory assumes short-ranged dynamic constraints to be the essential feature of supercooled liquids and draws much of its conclusions from the study of kinetically constrained models. While deceptively simple, these…

Materials Science · Physics 2012-06-12 Thomas Speck , David Chandler

Signatures of glassy dynamics have been identified experimentally for a rich variety of materials in which molecular networks provide rigidity. Here we present a theoretical framework to study the glassy behavior of both passive and active…

Statistical Mechanics · Physics 2013-03-26 Shenshen Wang , Peter G. Wolynes

Plastic rearrangements play a crucial role in the characterization of soft-glassy materials, such as emulsions and foams. Based on numerical simulations of soft-glassy systems, we study the dynamics of plastic rearrangements at the…

Soft Condensed Matter · Physics 2014-10-27 R. Benzi , M. Sbragaglia , A. Scagliarini , P. Perlekar , M. Bernaschi , S. Succi , F. Toschi

Regulatory networks consist of interacting molecules with a high degree of mutual chemical specificity. How can these molecules evolve when their function depends on maintenance of interactions with cognate partners and simultaneous…

Populations and Evolution · Quantitative Biology 2017-11-01 Tamar Friedlander , Roshan Prizak , Nicholas H. Barton , Gašper Tkačik

Cells in tissues can organize into a broad spectrum of structures according to their function. Drastic changes of organization, such as epithelial-mesenchymal transitions or the formation of spheroidal aggregates, are often associated…

Biological Physics · Physics 2016-12-22 Bart Smeets , Ricard Alert , Jiri Pesek , Ignacio Pagonabarraga , Herman Ramon , Romaric Vincent

Interactions between neighboring cells are essential for generating or refining patterns in a number of biological systems. We propose a discrete filtering approach to predict how networks of cells modulate spatially varying input signals…

Tissues and Organs · Quantitative Biology 2019-02-14 Melinda Liu Perkins , Murat Arcak

Evolutionary transitions occur when previously-independent replicating entities unite to form more complex individuals. Such transitions have profoundly shaped natural evolutionary history and occur in two forms: fraternal transitions…

Populations and Evolution · Quantitative Biology 2023-10-10 Matthew Andres Moreno , Charles Ofria

In this article we study a simple, purely topological, cellular model which is allowed to evolve through a Glauber-Kawasaki process. We find a non-thermodynamic transition to a glassy phase in which the energy (defined as the square of the…

Disordered Systems and Neural Networks · Physics 2009-10-31 Lexie Davison , David Sherrington
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