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As artificial intelligence (AI) becomes increasingly embedded in healthcare delivery, this chapter explores the critical aspects of developing reliable and ethical Clinical Decision Support Systems (CDSS). Beginning with the fundamental…

Artificial Intelligence · Computer Science 2025-02-18 Muhammet Alkan , Idris Zakariyya , Samuel Leighton , Kaushik Bhargav Sivangi , Christos Anagnostopoulos , Fani Deligianni

Research on decision support applications in healthcare, such as those related to diagnosis, prediction, treatment planning, etc., have seen enormously increased interest recently. This development is thanks to the increase in data…

Machine Learning · Computer Science 2021-03-25 Jussi Tohka , Mark van Gils

Decision support systems seek to enable informed decision-making. In the recent years, automated planning techniques have been leveraged to empower such systems to better aid the human-in-the-loop. The central idea for such decision support…

Artificial Intelligence · Computer Science 2022-06-07 Karthik Valmeekam , Sarath Sreedharan , Sailik Sengupta , Subbarao Kambhampati

Navigating health questions can be daunting in the modern information landscape. Large language models (LLMs) may provide tailored, accessible information, but also risk being inaccurate, biased or misleading. We present insights from 4…

Computational agents support humans in many areas of life and are therefore found in heterogeneous contexts. This means they operate in rapidly changing environments and can be confronted with huge state and action spaces. In order to…

Artificial Intelligence · Computer Science 2023-08-31 Nicole Merkle , Ralf Mikut

Statistical methods are indispensable to scientific inference. However, there exists a longstanding tension across a wide range of scientific disciplines about the role that ``context'' should play in the application of statistical methods…

Applications · Statistics 2026-04-06 Ashley I Naimi

Recommender Systems (RecSys) have become indispensable in numerous applications, profoundly influencing our everyday experiences. Despite their practical significance, academic research in RecSys often abstracts the formulation of research…

Information Retrieval · Computer Science 2024-06-25 Aixin Sun

Advances in machine learning have created new opportunities to develop artificial intelligence (AI)-based clinical decision support systems using past clinical data and improve diagnosis decisions in life-threatening illnesses such breast…

Human-Computer Interaction · Computer Science 2024-12-17 Olya Rezaeian , Onur Asan , Alparslan Emrah Bayrak

Recently there has been a surge of interest in operations research (OR) and the machine learning (ML) community in combining prediction algorithms and optimization techniques to solve decision-making problems in the face of uncertainty.…

Optimization and Control · Mathematics 2025-11-11 Utsav Sadana , Abhilash Chenreddy , Erick Delage , Alexandre Forel , Emma Frejinger , Thibaut Vidal

Artificial intelligence (AI) systems are increasingly used for providing advice to facilitate human decision making in a wide range of domains, such as healthcare, criminal justice, and finance. Motivated by limitations of the current…

Artificial Intelligence · Computer Science 2023-07-04 Gali Noti , Yiling Chen

In time-critical settings such as assistive driving, assistants often rely on alerts or haptic signals to prompt rapid human attention, but these cues usually leave humans to interpret situations and decide responses independently,…

Robotics · Computer Science 2025-09-10 Ya-Chuan Hsu , Jonathan DeCastro , Andrew Silva , Guy Rosman

Computer-aided methods have shown added value for diagnosing and predicting brain disorders and can thus support decision making in clinical care and treatment planning. This chapter will provide insight into the type of methods, their…

A growing number of researchers suggest that software process must be tailored to a project's context to achieve maximal performance. Researchers have studied 'context' in an ad-hoc way, with focus on those contextual factors that appear to…

Software Engineering · Computer Science 2021-02-19 Diana Kirk , Stephen G. MacDonell

Socially Assistive Robots (SARs) have shown promising potential in therapeutic scenarios as decision-making instructors or motivational companions. In human-human therapy, experts often communicate the thought process behind the decisions…

Robotics · Computer Science 2023-03-27 Carl Bettosi , Kefan Chen , Ryan Shah , Lynne Baillie

We propose a digital twin approach to improve healthcare decision support systems with a combination of domain knowledge and data. Domain knowledge helps build decision thresholds that doctors can use to determine a risk or recommend a…

Artificial Intelligence · Computer Science 2019-10-31 Dattaraj Jagdish Rao , Shraddha Mane

The analysis of decision making under uncertainty is closely related to the analysis of probabilistic inference. Indeed, much of the research into efficient methods for probabilistic inference in expert systems has been motivated by the…

Artificial Intelligence · Computer Science 2013-03-25 Ross D. Shachter , Mark Alan Peot

Cardiotoxicity induced by cancer treatment has become a major clinical concern, affecting the long-term survival and quality of life of cancer patients. Effective clinical decision-making, including the detection of cancer treatment-induced…

Human-Computer Interaction · Computer Science 2024-08-08 Siyi Wu , Weidan Cao , Shihan Fu , Bingsheng Yao , Ziqi Yang , Changchang Yin , Varun Mishra , Daniel Addison , Ping Zhang , Dakuo Wang

Visualization as a discipline often grapples with generalization by reasoning about how study results on the efficacy of a tool in one context might apply to another context. This work offers an account of the logic of generalization in…

Human-Computer Interaction · Computer Science 2025-08-12 Alex Kale

Large language models (LLMs) have shown considerable potential in supporting medical diagnosis. However, their effective integration into clinical workflows is hindered by physicians' difficulties in perceiving and trusting LLM…

Human-Computer Interaction · Computer Science 2026-01-28 Yuansong Xu , Yichao Zhu , Haokai Wang , Yuchen Wu , Yang Ouyang , Hanlu Li , Wenzhe Zhou , Xinyu Liu , Chang Jiang , Quan Li

This paper extends my research applying statistical decision theory to treatment choice with sample data, using maximum regret to evaluate the performance of treatment rules. The specific new contribution is to study as-if optimization…

Econometrics · Economics 2021-10-05 Charles F. Manski