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In this paper, we present an automated approach for segmenting multiple sclerosis (MS) lesions from multi-modal brain magnetic resonance images. Our method is based on a deep end-to-end 2D convolutional neural network (CNN) for slice-based…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Shahab Aslani , Michael Dayan , Loredana Storelli , Massimo Filippi , Vittorio Murino , Maria A Rocca , Diego Sona

Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of the central nervous system, characterized by the appearance of focal lesions in the white and gray matter that topographically correlate with an individual…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Yang Ma , Chaoyi Zhang , Mariano Cabezas , Yang Song , Zihao Tang , Dongnan Liu , Weidong Cai , Michael Barnett , Chenyu Wang

Magnetic resonance imaging is a fundamental tool to reach a diagnosis of multiple sclerosis and monitoring its progression. Although several attempts have been made to segment multiple sclerosis lesions using artificial intelligence, fully…

Objective: Multiple Sclerosis (MS) is an autoimmune, and demyelinating disease that leads to lesions in the central nervous system. This disease can be tracked and diagnosed using Magnetic Resonance Imaging (MRI). Up to now a multitude of…

Image and Video Processing · Electrical Eng. & Systems 2022-01-07 Mehdi SadeghiBakhi , Hamidreza Pourreza , Hamidreza Mahyar

Introduction: Multiple Sclerosis (MS) is a chronic disease that affects millions of people across the globe. MS can critically affect different organs of the central nervous system such as the eyes, the spinal cord, and the brain.…

Image and Video Processing · Electrical Eng. & Systems 2023-02-21 Atif Shah , Maged S. Al-Shaibani , Moataz Ahmad , Reem Bunyan

Assessment of lesions and their longitudinal progression from brain magnetic resonance (MR) images plays a crucial role in diagnosing and monitoring multiple sclerosis (MS). Machine learning models have demonstrated a great potential for…

Image and Video Processing · Electrical Eng. & Systems 2024-10-03 Berke Doga Basaran , Xinru Zhang , Paul M. Matthews , Wenjia Bai

Multiple sclerosis is an inflammatory autoimmune demyelinating disease that is characterized by lesions in the central nervous system. Typically, magnetic resonance imaging (MRI) is used for tracking disease progression. Automatic image…

Image and Video Processing · Electrical Eng. & Systems 2020-08-06 Nils Gessert , Julia Krüger , Roland Opfer , Ann-Christin Ostwaldt , Praveena Manogaran , Hagen H. Kitzler , Sven Schippling , Alexander Schlaefer

Lesion segmentation is a core task for quantitative analysis of MRI scans of Multiple Sclerosis patients. The recent success of deep learning techniques in a variety of medical image analysis applications has renewed community interest in…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Huahong Zhang , Ipek Oguz

Efficient and accurate whole-brain lesion segmentation remains a challenge in medical image analysis. In this work, we revisit MeshNet, a parameter-efficient segmentation model, and introduce a novel multi-scale dilation pattern with an…

Image and Video Processing · Electrical Eng. & Systems 2025-03-10 Alex Fedorov , Yutong Bu , Xiao Hu , Chris Rorden , Sergey Plis

Accurately segmenting a variety of clinically significant lesions from whole body computed tomography (CT) scans is a critical task on precision oncology imaging, denoted as universal lesion segmentation (ULS). Manual annotation is the…

Image and Video Processing · Electrical Eng. & Systems 2021-05-05 Youbao Tang , Jinzheng Cai , Ke Yan , Lingyun Huang , Guotong Xie , Jing Xiao , Jingjing Lu , Gigin Lin , Le Lu

Assessing lesions and tracking their progression over time in brain magnetic resonance (MR) images is essential for diagnosing and monitoring multiple sclerosis (MS). Machine learning models have shown promise in automating the segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Berke Doga Basaran , Paul M. Matthews , Wenjia Bai

Multiple Sclerosis (MS) is a chronic autoimmune disease that can significantly reduce the quality of life of a patient. Existing treatment options can only help slow down the progression of the disease. Therefore, early detection and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Abdul Basit , Ashir Rashid , Muhammad Abdullah Hanif , Muhammad Shafique

Segmenting an entire 3D image often has high computational complexity and requires large memory consumption; by contrast, performing volumetric segmentation in a slice-by-slice manner is efficient but does not fully leverage the 3D data. To…

Computer Vision and Pattern Recognition · Computer Science 2021-05-11 Rutu Gandhi , Yi Hong

MRI tumor segmentation remains a critical challenge in medical imaging, where volumetric analysis faces unique computational demands due to the complexity of 3D data. The spatially sequential arrangement of adjacent MRI slices provides…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Jiacheng Lu , Hui Ding , Shiyu Zhang , Guoping Huo

Manual segmentation of rodent brain lesions from magnetic resonance images (MRIs) is an arduous, time-consuming and subjective task that is highly important in pre-clinical research. Several automatic methods have been developed for…

Image and Video Processing · Electrical Eng. & Systems 2019-08-26 Juan Miguel Valverde , Artem Shatillo , Riccardo de Feo , Olli Gröhn , Alejandra Sierra , Jussi Tohka

Deep neural networks (DNN) have shown promises in the lesion segmentation of multiple sclerosis (MS) from multicontrast MRI including T1, T2, proton density (PD) and FLAIR sequences. However, one challenge in deploying such networks into…

Computer Vision and Pattern Recognition · Computer Science 2018-11-20 Yushan Feng , Huitong Pan , Craig Meyer , Xue Feng

Multiple sclerosis is one of the most common chronic neurological diseases affecting the central nervous system. Lesions produced by the MS can be observed through two modalities of magnetic resonance (MR), known as T2W and FLAIR sequences,…

Signal Processing · Electrical Eng. & Systems 2022-12-16 Antonio Falvo , Danilo Comminiello , Simone Scardapane , Michele Scarpiniti , Aurelio Uncini

Multiple Sclerosis (MS) is an autoimmune disease that leads to lesions in the central nervous system. Magnetic resonance (MR) images provide sufficient imaging contrast to visualize and detect lesions, particularly those in the white…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Snehashis Roy , John A. Butman , Daniel S. Reich , Peter A. Calabresi , Dzung L. Pham

The detection of new multiple sclerosis (MS) lesions is an important marker of the evolution of the disease. The applicability of learning-based methods could automate this task efficiently. However, the lack of annotated longitudinal data…

Image and Video Processing · Electrical Eng. & Systems 2022-06-17 Reda Abdellah Kamraoui , Boris Mansencal , José V Manjon , Pierrick Coupé
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