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During cancer progression, malignant cells accumulate somatic mutations that can lead to genetic aberrations. In particular, evolutionary events akin to segmental duplications or deletions can alter the copy-number profile (CNP) of a set of…

Genomics · Quantitative Biology 2020-02-27 Garance Cordonnier , Manuel Lafond

Deep generative models are tremendously successful in learning low-dimensional latent representations that well-describe the data. These representations, however, tend to much distort relationships between points, i.e. pairwise distances…

Machine Learning · Computer Science 2018-09-14 Tao Yang , Georgios Arvanitidis , Dongmei Fu , Xiaogang Li , Søren Hauberg

Functions of chemical composition are complex and discrete in nature making it impossible to optimize them with gradient methods. Genetic algorithms, which do not use derivative information, are used to maximize the thermal conductivity of…

Materials Science · Physics 2018-01-30 Alexander Kerr , Kieran Mullen

In this article we introduce Graph Generation, an enhanced Column Generation (CG) algorithm for solving expanded linear programming relaxations of mixed integer linear programs. To apply Graph Generation, we must be able to map any given…

Optimization and Control · Mathematics 2021-10-05 Julian Yarkony , Naveed Haghani , Amelia Regan

Machine learning and optimization algorithms have been widely applied in the design and optimization for photonic devices. In this article, we briefly review recent progress of this field of research and show some data-driven applications…

Optics · Physics 2020-07-15 Tian Zhang , Qi Liu , Yihang Dan , Shuai Yu , Xu Han , Jian Dai , Kun Xu

Twisted permutation codes, introduced recently by the second and third authors, are frequency permutation arrays. They are similar to repetition permutation codes, in that they are obtained by a repetition construction applied to a smaller…

Combinatorics · Mathematics 2015-11-24 Marzieh Akbari , Neil I. Gillespie , Cheryl E. Praeger

The evaluation of the minimum distance of linear block codes remains an open problem in coding theory, and it is not easy to determine its true value by classical methods, for this reason the problem has been solved in the literature with…

Information Theory · Computer Science 2013-03-19 Mohamed Askali , Ahmed Azouaoui , Saïd Nouh , Mostafa Belkasmi

We perform an extended numerical search for practical fermion-to-qubit encodings with error correcting properties. Ideally, encodings should strike a balance between a number of the seemingly incompatible attributes, such as having a high…

Quantum Physics · Physics 2024-05-29 Fedor Simkovic , Martin Leib , Francisco Revson F. Pereira

The study of genetic map linearization leads to a combinatorial hard problem, called the {\em minimum breakpoint linearization} (MBL) problem. It is aimed at finding a linearization of a partial order which attains the minimum breakpoint…

Genomics · Quantitative Biology 2015-02-26 Xin Chen

This paper investigates the influence of genotype size on evolutionary algorithms' performance. We consider genotype compression (where genotype is smaller than phenotype) and expansion (genotype is larger than phenotype) and define…

Neural and Evolutionary Computing · Computer Science 2021-05-26 Lucija Planinic , Marko Djurasevic , Luca Mariot , Domagoj Jakobovic , Stjepan Picek , Carlos Coello Coello

After observing a snapshot of a social network, a link prediction (LP) algorithm identifies node pairs between which new edges will likely materialize in future. Most LP algorithms estimate a score for currently non-neighboring node pairs,…

Social and Information Networks · Computer Science 2021-03-30 Indradyumna Roy , Abir De , Soumen Chakrabarti

Predicting the cheapest sample size for the optimal stratification in multivariate survey design is a problem in cases where the population frame is large. A solution exists that iteratively searches for the minimum sample size necessary to…

Methodology · Statistics 2018-06-18 Mervyn O'Luing , Steven Prestwich , S. Armagan Tarim

A permutation graph is the intersection graph of a set of segments between two parallel lines. In other words, they are defined by a permutation $\pi$ on $n$ elements, such that $u$ and $v$ are adjacent if an only if $u<v$ but…

Data Structures and Algorithms · Computer Science 2024-07-18 Paweł Gawrychowski , Wojciech Janczewski

The minimum distance is one of the most important combinatorial characterizations of a code. The maximum likelihood decoding problem is one of the most important algorithmic problems of a code. While these problems are known to be hard for…

Information Theory · Computer Science 2016-08-31 Qi Cheng

We propose a new compression scheme for genomic data given as sequence fragments called reads. The scheme uses a reference genome at the decoder side only, freeing the encoder from the burdens of storing references and performing…

Information Theory · Computer Science 2023-02-10 Yotam Gershon , Yuval Cassuto

Efficient resource allocation and optical switching promise high key rates, network adaptability, and cost reduction in repeaterless quantum communication networks. However, identifying optimal switching configurations remains a significant…

In several multiobjective decision problems Pairwise Comparison Matrices (PCM) are applied to evaluate the decision variants. The problem that arises very often is the inconsistency of a given PCM. In such a situation it is important to…

Optimization and Control · Mathematics 2024-12-10 Marcin Anholcer , Janos Fülöp

Graph neural networks based on iterative one-hop message passing have been shown to struggle in harnessing the information from distant nodes effectively. Conversely, graph transformers allow each node to attend to all other nodes directly,…

Machine Learning · Computer Science 2024-06-06 Yuhui Ding , Antonio Orvieto , Bobby He , Thomas Hofmann

Two completely new algorithms for generating permutations, shift-cursor algorithm and level algorithm, and their efficient implementations are presented in this paper. One implementation of the shift cursor algorithm gives an optimal…

Data Structures and Algorithms · Computer Science 2007-05-23 Jie Gao , Dianjun Wang

Many algorithms have been developed for enumerating various combinatorial objects in time exponentially less than the number of objects. Two common classes of algorithms are dynamic programming and the transfer matrix method. This paper…

Combinatorics · Mathematics 2017-05-16 Andrew R. Conway