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In the infectious disease literature, significant effort has been devoted to studying dynamics at a single scale. For example, compartmental models describing population-level dynamics are often formulated using differential equations. In…

Populations and Evolution · Quantitative Biology 2025-04-16 Yuan Yin , Jennifer A. Flegg , Mark B. Flegg

We propose a method for efficiently coupling the finite element method with atomistic simulations, while using molecular dynamics or kinetic Monte Carlo techniques. Our method can dynamically build an optimized unstructured mesh that…

Computational Engineering, Finance, and Science · Computer Science 2018-05-23 Mihkel Veske , Andreas Kyritsakis , Kristjan Eimre , Vahur Zadin , Alvo Aabloo , Flyura Djurabekova

In this paper, we have established a unified framework of multistage parameter estimation. We demonstrate that a wide variety of statistical problems such as fixed-sample-size interval estimation, point estimation with error control,…

Statistics Theory · Mathematics 2013-11-05 Xinjia Chen

Modeling real-world problems with partial differential equations (PDEs) is a prominent topic in scientific machine learning. Classic solvers for this task continue to play a central role, e.g. to generate training data for deep learning…

Machine Learning · Computer Science 2024-06-10 Tim Weiland , Marvin Pförtner , Philipp Hennig

Within recent years, considerable progress has been made regarding high-performance solvers for Partial Differential Equations (PDEs), yielding potential gains in efficiency compared to industry standard tools. However, the latter largely…

Numerical Analysis · Mathematics 2024-02-20 Patrick Zimbrod , Michael Fleck , Johannes Schilp

Time series is a special type of sequence data, a sequence of real-valued random variables collected at even intervals of time. The real-world multivariate time series comes with noises and contains complicated local and global temporal…

Machine Learning · Computer Science 2023-11-21 Site Mo , Haoxin Wang , Bixiong Li , Songhai Fan , Yuankai Wu , Xianggen Liu

Computational chemistry allows researchers to experiment in sillico: by running a computer simulations of a biological or chemical processes of interest. Molecular dynamics with molecular mechanics model of interactions simulates N-body…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-03-03 Jana Pazúriková

For the study of complex synthetic and biological molecular systems by computer simulations one is still restricted to simple model systems or to by far too small time scales. To overcome this problem multiscale techniques are being…

Statistical Mechanics · Physics 2007-05-23 Matej Praprotnik , Kurt Kremer , Luigi Delle Site

Understanding the capabilities of classical simulation methods is key to identifying where quantum computers are advantageous. Not only does this ensure that quantum computers are used only where necessary, but also one can potentially…

In this thesis, we develop multiscale models for particle simulations in population dynamics. These models are characterised by prescribing particle motion on two spatial scales: microscopic and macroscopic. At the microscopic level, each…

Computational Engineering, Finance, and Science · Computer Science 2016-09-14 Omar Richardson

The trade-off between optimality and complexity has been one of the most important challenges in the field of robust Model Predictive Control (MPC). To address the challenge, we propose a flexible robust MPC scheme by synergizing the…

Systems and Control · Electrical Eng. & Systems 2021-03-25 Sankaranarayanan Subramanian , Sergio Lucia , Radoslav Paulen , Sebastian Engell

The modeling of cracks has been an intensely researched topic for decades - both from the mechanical as well as from the mathematics point of view. As far as the modeling of sharp cracks/interfaces is concerned, the resulting free boundary…

Analysis of PDEs · Mathematics 2022-11-24 Samira Boddin , Felix Rörentrop , Dorothee Knees , Jörn Mosler

Optimization of expensive computer models with the help of Gaussian process emulators in now commonplace. However, when several (competing) objectives are considered, choosing an appropriate sampling strategy remains an open question. We…

Optimization and Control · Mathematics 2013-10-03 Victor Picheny

Cosmological simulations require the use of a multiple time-stepping scheme. Without such a scheme, cosmological simulations would be impossible due to their high level of dynamic range; over eleven orders of magnitude in density. Such a…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-07-05 Josh Borrow , Richard G. Bower , Peter W. Draper , Pedro Gonnet , Matthieu Schaller

Simulation is a fundamental research tool in the computer architecture field. These kinds of tools enable the exploration and evaluation of architectural proposals capturing the most relevant aspects of the highly complex systems under…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-02-11 Adrian Colaso , Pablo Prieto , Jose-Angel Herrero , Pablo Abad , Valentin Puente , Jose-Angel Gregorio

There are many astrophysical and laboratory scenarios where kinetic effects play an important role. These range from astrophysical shocks and plasma shell collisions, to high intensity laser-plasma interactions, with applications to fast…

Plasma Physics · Physics 2009-11-13 R. A. Fonseca , S. F. Martins , L. O. Silva , J. W. Tonge , F. S. Tsung , W. B. Mori

Scalable and efficient numerical simulations continue to gain importance, as computation is firmly established as the third pillar of discovery, alongside theory and experiment. Meanwhile, the performance of computing hardware grows through…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-06-26 Pietro Incardona , Antonio Leo , Yaroslav Zaluzhnyi , Rajesh Ramaswamy , Ivo F. Sbalzarini

We consider large-scale Markov decision processes (MDPs) with parameter uncertainty, under the robust MDP paradigm. Previous studies showed that robust MDPs, based on a minimax approach to handle uncertainty, can be solved using dynamic…

Machine Learning · Computer Science 2013-06-27 Aviv Tamar , Huan Xu , Shie Mannor

Simulation schemes for probabilistic inference in Bayesian belief networks offer many advantages over exact algorithms; for example, these schemes have a linear and thus predictable runtime while exact algorithms have exponential runtime.…

Artificial Intelligence · Computer Science 2013-02-28 Remco R. Bouckaert

In this work, we present a high-fidelity and efficient point-particle direct numerical simulation framework based on a multi-block overset curvilinear grid system, enabling large-scale Lagrangian particle tracking in complex geometries with…

Fluid Dynamics · Physics 2025-09-10 Taiyang Wang , Baoqing Meng , Baolin Tian , Yaomin Zhao
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