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Spatially aligning medical images from different modalities remains a challenging task, especially for intraoperative applications that require fast and robust algorithms. We propose a weakly-supervised, label-driven formulation for…

Computer Vision and Pattern Recognition · Computer Science 2018-06-05 Yipeng Hu , Marc Modat , Eli Gibson , Nooshin Ghavami , Ester Bonmati , Caroline M. Moore , Mark Emberton , J. Alison Noble , Dean C. Barratt , Tom Vercauteren

Multi-modality image registration is one of the most underlined processes in medical image analysis. Recently, convolutional neural networks (CNNs) have shown significant potential in deformable registration. However, the lack of voxel-wise…

Computer Vision and Pattern Recognition · Computer Science 2020-02-06 Yechong Huang , Tao Song , Jiahang Xu , Yinan Chen , Xiahai Zhuang

We propose an unsupervised deep learning method for atlas based registration to achieve segmentation and spatial alignment of the embryonic brain in a single framework. Our approach consists of two sequential networks with a specifically…

Image and Video Processing · Electrical Eng. & Systems 2020-05-14 Wietske A. P. Bastiaansen , Melek Rousian , Régine P. M. Steegers-Theunissen , Wiro J. Niessen , Anton Koning , Stefan Klein

Medical imaging is a domain which suffers from a paucity of manually annotated data for the training of learning algorithms. Manually delineating pathological regions at a pixel level is a time consuming process, especially in 3D images,…

Computer Vision and Pattern Recognition · Computer Science 2018-11-28 Christopher Bowles , Roger Gunn , Alexander Hammers , Daniel Rueckert

The deformable registration of images of different modalities, essential in many medical imaging applications, remains challenging. The main challenge is developing a robust measure for image overlap despite the compared images capturing…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Joel Honkamaa , Pekka Marttinen

Understanding three-dimensional (3D) geometries from two-dimensional (2D) images without any labeled information is promising for understanding the real world without incurring annotation cost. We herein propose a novel generative model,…

Computer Vision and Pattern Recognition · Computer Science 2020-05-26 Atsuhiro Noguchi , Tatsuya Harada

Robust and accurate 2D/3D registration, which aligns preoperative models with intraoperative images of the same anatomy, is crucial for successful interventional navigation. To mitigate the challenge of a limited field of view in…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Yuxin Cui , Rui Song , Yibin Li , Max Q. -H. Meng , Zhe Min

State-of-the-art deep learning-based registration methods employ three different learning strategies: supervised learning, which requires costly manual annotations, unsupervised learning, which heavily relies on hand-crafted similarity…

Computer Vision and Pattern Recognition · Computer Science 2023-07-21 Alexander Bigalke , Lasse Hansen , Tony C. W. Mok , Mattias P. Heinrich

Medical image segmentation is a relevant task as it serves as the first step for several diagnosis processes, thus it is indispensable in clinical usage. Whilst major success has been reported using supervised techniques, they assume a…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Lihao Liu , Angelica I Aviles-Rivero , Carola-Bibiane Schönlieb

Current color fundus image registration approaches are limited, among other things, by the lack of labeled data, which is even more significant in the medical domain, motivating the use of unsupervised learning. Therefore, in this work, we…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 David Rivas-Villar , Álvaro S. Hervella , José Rouco , Jorge Novo

We present recursive cascaded networks, a general architecture that enables learning deep cascades, for deformable image registration. The proposed architecture is simple in design and can be built on any base network. The moving image is…

Computer Vision and Pattern Recognition · Computer Science 2020-03-26 Shengyu Zhao , Yue Dong , Eric I-Chao Chang , Yan Xu

Non-rigid inter-modality registration can facilitate accurate information fusion from different modalities, but it is challenging due to the very different image appearances across modalities. In this paper, we propose to train a non-rigid…

Computer Vision and Pattern Recognition · Computer Science 2018-05-01 Xiaohuan Cao , Jianhua Yang , Li Wang , Zhong Xue , Qian Wang , Dinggang Shen

As digital medical imaging becomes more prevalent and archives increase in size, representation learning exposes an interesting opportunity for enhanced medical decision support systems. On the other hand, medical imaging data is often…

Computer Vision and Pattern Recognition · Computer Science 2018-07-25 Eduardo Pinho , Carlos Costa

Multi-modal image registration plays a critical role in precision medicine but faces challenges from non-linear intensity relationships and local optima. While deep learning models enable rapid inference, they often suffer from…

Image and Video Processing · Electrical Eng. & Systems 2026-04-14 Boya Wang , Ruizhe Li , Chao Chen , Xin Chen

In this work, we propose a self-supervised learning method for affine image registration on 3D medical images. Unlike optimisation-based methods, our affine image registration network (AIRNet) is designed to directly estimate the…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Evelyn Chee , Zhenzhou Wu

Generative adversarial networks (GANs) are unsupervised Deep Learning approach in the computer vision community which has gained significant attention from the last few years in identifying the internal structure of multimodal medical…

Image and Video Processing · Electrical Eng. & Systems 2020-05-22 Nripendra Kumar Singh , Khalid Raza

We propose to learn a low-dimensional probabilistic deformation model from data which can be used for registration and the analysis of deformations. The latent variable model maps similar deformations close to each other in an encoding…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Julian Krebs , Hervé Delingette , Boris Mailhé , Nicholas Ayache , Tommaso Mansi

One of the fundamental challenges in supervised learning for multimodal image registration is the lack of ground-truth for voxel-level spatial correspondence. This work describes a method to infer voxel-level transformation from…

Deformable medical image registration is traditionally formulated as an optimization problem. While classical methods solve this problem iteratively, recent learning-based approaches use recurrent neural networks (RNNs) to mimic this…

Image and Video Processing · Electrical Eng. & Systems 2025-07-09 Yi Zhang , Yidong Zhao , Qian Tao

Optimization techniques have been widely used in deformable registration, allowing for the incorporation of similarity metrics with regularization mechanisms. These regularization mechanisms are designed to mitigate the effects of trivial…

Computer Vision and Pattern Recognition · Computer Science 2014-04-10 Martin Rajchl , John S. H. Baxter , Wu Qiu , Ali R. Khan , Aaron Fenster , Terry M. Peters , Jing Yuan