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Magnetic resonance spectroscopy (MRS) is an important clinical imaging method for diagnosis of diseases. MRS spectrum is used to observe the signal intensity of metabolites or further infer their concentrations. Although the magnetic…

The condensation of biomolecules into biomolecular condensates via liquid-liquid phase separation (LLPS) is a ubiquitous mechanism that drives cellular organization. To enable these functions, biomolecules have evolved to drive LLPS and…

Biomolecules · Quantitative Biology 2020-03-04 Erik W. Martin , Jesse B. Hopkins , Tanja Mittag

The motivation of this work is the use of non-invasive and low cost techniques to obtain a faster and more accurate diagnosis of systemic sclerosis (SSc), rheumatic, autoimmune, chronic and rare disease. The technique in question is Near…

Because optical systems have huge bandwidth and are capable of generating low noise short pulses they are ideal for undersampling multi-band signals that are located within a very broad frequency range. In this paper we propose a new scheme…

Optics · Physics 2009-11-13 Amir Rosenthal , Alex Linden , Moshe Horowitz

We demonstrate a wide-band all-optical method of nanoscale magnetic resonance (MR) spectroscopy under ambient conditions. Our method relies on cross-relaxation between a probe spin, the electronic spin of a nitrogen-vacancy centre in…

Raman scattering, an inelastic scattering mechanism, provides information about molecular excitation energies and can be used to identify chemical compounds. Albeit being a powerful analysis tool, especially for label-free biomedical…

One of the great challenges in biology is to observe, at sufficient detail, the real-time workings of the cell. Many methods exist to do cell measurements invasively. For example, mass spectrometry has tremendous mass sensitivity but…

Quantitative Methods · Quantitative Biology 2017-10-23 Jan G. Korvink , Neil MacKinnon

Despite its versatility and high chemical specificity, conventional NMR spectroscopy is limited in measurement throughput due to the need for high-homogeneity magnetic fields, necessitating sequential sample analysis, and bulky devices.…

Instrumentation and Detectors · Physics 2024-07-02 Blake Andrews , Matthew Lai , Zhen Wang , Norihisa Kato , Michael Tayler , Emanuel Druga , Ashok Ajoy

Edge localised modes (ELMs) allow maintaining sufficient purity of tokamak H-mode plasmas and thus enable stationary H-mode. On the other hand in a future device ELMs may cause divertor power flux densities far in excess of tolerable…

Real-time probing of electrons can uncover intricate relaxation mechanisms and many-body interactions hidden in strongly correlated materials. While experimenters have used ultrafast optical pump-probe methods in bulk materials, laser…

Mesoscale and Nanoscale Physics · Physics 2024-01-23 H. M. Yoo , M. Korkusinski , D. Miravet , K. W. Baldwin , K. West , L. Pfeiffer , P. Hawrylak , R. C. Ashoori

Magnetic Resonance Spectroscopic Imaging (MRSI) is a clinical imaging modality for measuring tissue metabolite levels in-vivo. An accurate estimation of spectral parameters allows for better assessment of spectral quality and metabolite…

Computer Vision and Pattern Recognition · Computer Science 2018-05-28 Dhritiman Das , Eduardo Coello , Rolf F Schulte , Bjoern H Menze

The majority of nuclei available for study in solid state Nuclear Magnetic Resonance have half-integer spin $I > 1/2 $, with corresponding electric quadrupole moment. As such, they may couple with a surrounding electric field gradient. This…

Materials Science · Physics 2009-05-19 William J. Brouwer , Michael C. Davis , Karl T. Mueller

In order to function reliably, synthetic molecular circuits require mechanisms that allow them to adapt to environmental disturbances. Least mean squares (LMS) schemes, such as commonly encountered in signal processing and control, provide…

Molecular Networks · Quantitative Biology 2017-01-04 Christoph Zechner , Mustafa Khammash

Classification and identification of amino acids in aqueous solutions is important in the study of biomacromolecules. Laser Induced Breakdown Spectroscopy (LIBS) uses high energy laser-pulses for ablation of chemical compounds whose…

Machine Learning · Computer Science 2021-05-26 Piyush K. Sharma , Gary Holness , Poopalasingam Sivakumar , Yuri Markushin , Noureddine Melikechi

Magnetic resonance spectroscopy is universally regarded as one of the most important tools in chemical and bio-medical research. However, sensitivity limitations typically restrict imaging resolution to length scales greater than 10 \mu m.…

Surface-enhanced Raman scattering (SERS) combines analyte-specificity and single-molecule sensitivity, but its potential is limited by slow readout where sophisticated nanosensors are analysed in a serial fashion, one particle at a time. We…

Functional magnetic resonance spectroscopy (fMRS) quantifies metabolic variations upon presentation of a stimulus and can therefore provide complementary information compared to functional magnetic resonance imaging (fMRI). However, to our…

Medical Physics · Physics 2020-01-24 Clémence Ligneul , Francisca F. Fernandes , Noam Shemesh

In the mixture of ultracold spin-1 atoms of two different species A and B (e.g., $^{23}$Na (A) and $^{87}$Rb (B)), inter-species singlet-pairing process ${\rm A}_{+1}+{\rm B}_{-1}\rightleftharpoons {\rm A}_{-1}+{\rm B}_{+1}$, can be induced…

Quantum Gases · Physics 2021-06-02 Jianwen Jie , Yonghong Yu , Dajun Wang , Peng Zhang

Magnetic Resonance Spectroscopy (MRS) provides valuable information to help with the identification and understanding of brain tumors, yet MRS is not a widely available medical imaging modality. Aiming to counter this issue, this research…

Computer Vision and Pattern Recognition · Computer Science 2018-08-24 Nathan J Olliverre , Guang Yang , Gregory Slabaugh , Constantino Carlos Reyes-Aldasoro , Eduardo Alonso

Simultaneous multislice (SMS) imaging is a one of the acceleration technique of magnetic resonance imaging. SMS requires accurate sensitivity distributions in the slice plane for each receiving coil. This requirement is difficult to satisfy…

Medical Physics · Physics 2024-03-04 Satoshi Ito , Yuki Sato , Naoya Endo , Shohei Ouchi