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Randomness is one of the important key concepts of statistics. In epidemiology or medical science, we investigate our hypotheses and interpret results through this statistical randomness. We hypothesized by imposing some conditions to this…

Methodology · Statistics 2020-02-11 T. Usuzaki , M. Shimoyama S. Chiba , S. Hotta

Consider a finite renewal process in the sense that interrenewal times are positive i.i.d. variables and the total number of renewals is a random variable, independent of interrenewal times. A finite point process can be obtained by…

Statistics Theory · Mathematics 2012-01-06 Nelson Antunes , Vladas Pipiras

We introduce and analyze a waiting time model for the accumulation of genetic changes. The continuous time conjunctive Bayesian network is defined by a partially ordered set of mutations and by the rate of fixation of each mutation. The…

Populations and Evolution · Quantitative Biology 2007-09-18 Niko Beerenwinkel , Seth Sullivant

We consider the discrete-time migration-recombination equation, a deterministic, nonlinear dynamical system that describes the evolution of the genetic type distribution of a population evolving under migration and recombination in a law of…

Probability · Mathematics 2021-03-30 Frederic Alberti , Ellen Baake , Ian Letter , Servet Martinez

We show that genealogical trees arising from a broad class of non-neutral models of population evolution converge to the Kingman coalescent under a suitable rescaling of time. As well as non-neutral biological evolution, our results apply…

Probability · Mathematics 2025-04-09 Jere Koskela , Paul A. Jenkins , Adam M. Johansen , Dario Spano

The distributed genome hypothesis states that the set of genes in a population of bacteria is distributed over all individuals that belong to the specific taxon. It implies that certain genes can be gained and lost from generation to…

Probability · Mathematics 2010-11-08 F. Baumdicker , W. R. Hess , P. Pfaffelhuber

In this article, we focus on Bienaym\'e-Galton-Watson processes with linear-fractional offspring distributions. At a fixed generation, we consider a sample of the individuals alive, drawn in two different ways: either through Bernoulli…

Probability · Mathematics 2025-06-24 Natalia Cardona-Tobón , Sandra Palau

We consider neutral evolution of a large population subject to changes in its population size. For a population with a time-variable carrying capacity we have computed the distributions of the total branch lengths of its sample genealogies.…

Populations and Evolution · Quantitative Biology 2012-06-13 A. Eriksson , B. Mehlig , M. Rafajlovic , S. Sagitov

These lecture notes introduce the statistical analysis of continuous-time generative models built from Markov dynamics. We begin with the stochastic-calculus foundations of score-based diffusion models, including time reversal, score…

Statistics Theory · Mathematics 2026-04-27 Eddie Aamari , Arthur Stéphanovitch

The development of coalescent theory paved the way to statistical inference from population genetic data. In the genomic era, however, coalescent models are limited due to the complexity of the underlying ancestral recombination graph. The…

Populations and Evolution · Quantitative Biology 2021-06-30 Julien Y. Dutheil

Coalescence processes have received a lot of attention in the context of conditional branching processes with fixed population size and non-overlapping generations. Here we focus on similar problems in the context of the standard…

Probability · Mathematics 2017-09-25 Nicolas Grosjean , Thierry Huillet

We describe briefly in this note a procedure for consistently estimating the marginal likelihood of a statistical model through a sample from the posterior distribution of the model parameters.

Statistics Theory · Mathematics 2014-06-12 Paulo C. Marques F

Motivated by applications in systems biology, we seek a probabilistic framework based on Markov processes to represent intracellular processes. We review the formal relationships between different stochastic models referred to in the…

Quantitative Methods · Quantitative Biology 2007-08-13 Mukhtar Ullah , Olaf Wolkenhauer

We prove the existence of the total length process for the genealogical tree of a population model with random size given by a quadratic stationary continuous-state branching processes. We also give, for the one-dimensional marginal, its…

Probability · Mathematics 2014-07-18 Hongwei Bi , Jean-François Delmas

We consider the problem of inferring a latent function in a probabilistic model of data. When dependencies of the latent function are specified by a Gaussian process and the data likelihood is complex, efficient computation often involve…

Machine Learning · Statistics 2018-07-23 Martin Tegner , Benjamin Bloem-Reddy , Stephen Roberts

We consider an exactly solvable model of branching random walk with random selection, which describes the evolution of a population with $N$ individuals on the real line. At each time step, every individual reproduces independently, and its…

Probability · Mathematics 2018-10-09 Aser Cortines , Bastien Mallein

The extremal process of a branching random walk is the point measure recording the position of particles alive at time $n$, shifted around the expected position of the minimal position. Madaule proved that this point measure converges, as…

Probability · Mathematics 2018-10-09 Bastien Mallein

Bertoin and Le Gall (2003) introduced a certain probability measure valued Markov process that describes the evolution of a population, such that a sample from this population would exhibit a genealogy given by the so-called…

Probability · Mathematics 2007-05-23 Andreas Nordvall Lagerås

We suggest a simple deterministic approximation for the growth of the favoured-allele frequency during a selective sweep. Using this approximation we introduce an accurate model for genetic hitch-hiking. Only when Ns < 10 (N is the…

Populations and Evolution · Quantitative Biology 2025-10-01 A. Eriksson , P. Fernstrom , B. Mehlig , S. Sagitov

We give a closed form of the discrete-time evolution of a recombination transformation in population genetics. This decomposition allows to define a Markov chain in a natural way. We describe the geometric decay rate to the limit…

Probability · Mathematics 2016-03-24 Servet Martinez
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