English
Related papers

Related papers: Reinforcement Learning Framework for Deep Brain St…

200 papers

Synthesizing physiologically-accurate human movement in a variety of conditions can help practitioners plan surgeries, design experiments, or prototype assistive devices in simulated environments, reducing time and costs and improving…

Training a deep neural network to maximize a target objective has become the standard recipe for successful machine learning over the last decade. These networks can be optimized with supervised learning, if the target objective is…

Machine Learning · Computer Science 2025-05-12 Bernhard Jaeger , Andreas Geiger

Feedback-driven recurrent spiking neural networks (RSNNs) are powerful computational models that can mimic dynamical systems. However, the presence of a feedback loop from the readout to the recurrent layer de-stabilizes the learning…

Artificial Intelligence · Computer Science 2022-05-30 Ankita Paul , Stefan Wagner , Anup Das

A universal approach is proposed for suppression of collective synchrony in a large population of interacting rhythmic units. We demonstrate that provided that the internal coupling is weak, stabilization of overall oscillations with…

Adaptation and Self-Organizing Systems · Physics 2011-11-08 Ming Luo , Yongjun Wu

Drawing an inspiration from behavioral studies of human decision making, we propose here a general parametric framework for a reinforcement learning problem, which extends the standard Q-learning approach to incorporate a two-stream…

Machine Learning · Computer Science 2019-11-14 Baihan Lin , Djallel Bouneffouf , Guillermo Cecchi

While Large Language Models (LLMs) have shown strong performance on clinical text understanding, they struggle with longitudinal prediction tasks such as dementia prognosis, which require reasoning over complex, non-monotonic symptom…

Computation and Language · Computer Science 2026-03-23 Choonghan Kim , Hyunmin Hwang , Hangeol Chang , Jaemin Kim , Jinse Park , Jae-Sung Lim , Jong Chul Ye

Working memory requires the brain to maintain information from the recent past to guide ongoing behavior. Neurons can contribute to this capacity by slowly integrating their inputs over time, creating persistent activity that outlasts the…

Neurons and Cognition · Quantitative Biology 2025-11-20 Nicoas Zucchet , Qianqian Feng , Axel Laborieux , Friedemann Zenke , Walter Senn , João Sacramento

Reinforcement learning (RL) is a popular machine learning paradigm for game playing, robotics control, and other sequential decision tasks. However, RL agents often have long learning times with high data requirements because they begin by…

Machine Learning · Computer Science 2021-02-05 Matthew E. Taylor , Nicholas Nissen , Yuan Wang , Neda Navidi

Deep reinforcement learning (DRL) has proven extremely useful in a large variety of application domains. However, even successful DRL-based software can exhibit highly undesirable behavior. This is due to DRL training being based on…

Machine Learning · Computer Science 2023-09-12 Ophir M. Carmel , Guy Katz

Safety alignment in large language models (LLMs) is achieved through fine-tuning mechanisms that regulate neuron activations to suppress harmful content. In this work, we propose a novel approach to induce disalignment by identifying and…

Machine Learning · Computer Science 2025-05-01 Yi Zhou , Wenpeng Xing , Dezhang Kong , Changting Lin , Meng Han

Recurrent Neural Networks (RNNs) are popular models of brain function. The typical training strategy is to adjust their input-output behavior so that it matches that of the biological circuit of interest. Even though this strategy ensures…

Neurons and Cognition · Quantitative Biology 2020-11-09 Alessandro Salatiello , Martin A. Giese

Reinforcement Learning (RL) for training Large Language Models is notoriously unstable. While recent studies attribute this to "training inference mismatch stemming" from inconsistent hybrid engines, standard remedies, such as Importance…

Machine Learning · Computer Science 2026-02-03 Yaxiang Zhang , Yingru Li , Jiacai Liu , Jiawei Xu , Ziniu Li , Qian Liu , Haoyuan Li

Assistive Robotics is a class of robotics concerned with aiding humans in daily care tasks that they may be inhibited from doing due to disabilities or age. While research has demonstrated that classical control methods can be used to…

Robotics · Computer Science 2022-11-09 Yash Jakhotiya , Iman Haque

Functional Electrical Stimulation (FES) can restore motion to a paralysed person's muscles. Yet, control stimulating many muscles to restore the practical function of entire limbs is an unsolved problem. Current neurostimulation engineering…

Machine Learning · Computer Science 2021-04-05 Nat Wannawas , Mahendran Subramanian , A. Aldo Faisal

Learning and decision making in the brain are key processes critical to survival, and yet are processes implemented by non-ideal biological building blocks which can impose significant error. We explore quantitatively how the brain might…

Neurons and Cognition · Quantitative Biology 2011-04-19 Jake Bouvrie , Jean-Jacques Slotine

Deep brain stimulation (DBS) has shown great promise toward treating motor symptoms caused by Parkinson's disease (PD), by delivering electrical pulses to the Basal Ganglia (BG) region of the brain. However, DBS devices approved by the U.S.…

Existing studies on constrained reinforcement learning (RL) may obtain a well-performing policy in the training environment. However, when deployed in a real environment, it may easily violate constraints that were originally satisfied…

Machine Learning · Computer Science 2024-05-06 Zhongchang Sun , Sihong He , Fei Miao , Shaofeng Zou

Recurrent neural network-based reinforcement learning systems are capable of complex motor control tasks such as locomotion and manipulation, however, much of their underlying mechanisms still remain difficult to interpret. Our aim is to…

Robotics · Computer Science 2023-06-29 Eugene R. Rush , Christoffer Heckman , Kaushik Jayaram , J. Sean Humbert

The emergence of powerful artificial intelligence is defining new research directions in neuroscience. To date, this research has focused largely on deep neural networks trained using supervised learning, in tasks such as image…

Artificial Intelligence · Computer Science 2020-07-09 Matthew Botvinick , Jane X. Wang , Will Dabney , Kevin J. Miller , Zeb Kurth-Nelson

The reward signal plays a central role in defining the desired behaviors of agents in reinforcement learning (RL). Rewards collected from realistic environments could be perturbed, corrupted, or noisy due to an adversary, sensor error, or…

Machine Learning · Computer Science 2025-03-12 Xi Chen , Zhihui Zhu , Andrew Perrault