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In SPECT imaging, the identification and detection of a lesion rely either on visual inspection of the reconstructed tomographic images or post-processing image analysis methods. Both approaches do not provide the capability to attribute a…

Image and Video Processing · Electrical Eng. & Systems 2020-08-31 Costas N. Papanicolas , Loizos Koutsantonis , Efstathios Stiliaris

The use of differential phase contrast (DPC) in scanning transmission electron microscopy (STEM) has shown much promise for directly investigating the functional properties of a material system, leveraging the natural coupling between the…

Materials Science · Physics 2025-12-04 Rafael V. Ferreira , Sebastian Calderon V. , Paulo J. Ferreira

Treatment planning systems at proton-therapy centres generally use X-ray computed tomography (CT) as primary imaging technique to infer the proton treatment doses to tumour and healthy tissues. However, proton stopping powers in the body,…

The PANOSETI experiment is an all-sky, all-the-time visible search for nanosecond to millisecond time-scale transients. The experiment will deploy observatory domes at several sites, each dome containing ~45 telescopes and covering ~4,440…

SPECT systems using pinhole apertures permit radiolabeled molecular distributions to be imaged in vivo in small animals. Nevertheless studying cardiovascular diseases by means of small animal models is very challenging. Specifically,…

Preclinical research and organ-dedicated applications require high-resolution positron emission tomography (PET) detectors to visualize small structures and understand biological processes at a finer level of detail. Current commercial…

Since the discovery of nuclear gamma-rays, its imaging has been limited to pseudo imaging, such as Compton Camera (CC) and coded mask. Pseudo imaging does not keep physical information (intensity, or brightness in Optics) along a ray, and…

PET provides in vivo molecular and functional imaging capability that is crucial to studying the interaction of plant with changing environment at the whole-plant level. We have developed a dedicated plant PET imager that features high…

Instrumentation and Detectors · Physics 2014-09-22 Qiang Wang , Aswin J. Mathews , Ke Li , Jie Wen , Sergey Komarov , Joseph A. O'Sullivan , Yuan-Chuan Tai

Multi-slat prompt-gamma camera is a promising tool for range monitoring during proton therapy. We report the results of a comprehensive simulation study analyzing the precision which is possible to reach with this camera in determination of…

Medical Physics · Physics 2021-01-20 A. Morozov , H. Simões , P. Crespo

Focused transmits are the most commonly used transmit strategy for echocardiograms, but suffer from relatively low frame rates, and in 3D, even lower volume rates. Fast imaging based on unfocused transmits has disadvantages such as motion…

Signal Processing · Electrical Eng. & Systems 2026-05-14 Wessel L. van Nierop , Oisín Nolan , Tristan S. W. Stevens , Ruud J. G. van Sloun

Scanning Helium Microscopy (SHeM) offers a combination of spatial and angular resolution via a pinhole-collimated beam of thermal energy, neutral helium-4 atoms for non-destructive imaging. This thesis introduces a novel 3D imaging mode,…

Applied Physics · Physics 2024-03-27 Aleksandar Radic

Neurological Positron Emission Tomography (PET) is a critical imaging modality for diagnosing and studying neurodegenerative diseases like Alzheimer's disease. However, the inherent low spatial resolution of PET images poses significant…

Medical Physics · Physics 2025-02-24 Matthew Tivnan , Quanzheng Li

The exponential growth of photonic quantum technologies is driving the demand of tools for measuring the quality of their information carriers. One of the most prominent is Stimulated Emission Tomography (SET), which uses classical coherent…

Quantum Physics · Physics 2020-04-22 Massimo Borghi

A Compton camera is the most promising approach for gamma-ray detection in the energy region from several hundred keV to MeV, especially for application in high energy astrophysics. In order to obtain good angular resolution, semiconductor…

This paper presents a novel image reconstruction pipeline for three-gamma (3-{\gamma}) positron emission tomography (PET) aimed at improving spatial resolution and reducing noise in nuclear medicine; the proposed Direct3{\gamma} pipeline…

Medical Physics · Physics 2025-06-23 Youness Mellak , Alexandre Bousse , Thibaut Merlin , Debora Giovagnoli , Dimitris Visvikis

Scanning transmission electron microscopy (STEM) has been extensively used for imaging complex materials down to atomic resolution. The most commonly employed STEM modality, annular dark-field imaging, produces easily-interpretable…

The GRIT (Granularity, Resolution, Identification, Transparency) Silicon array is intended to measure direct reactions. Its design is based on several layers (three layers in the forward direction, two backward) of custom-made trapezoidal…

Image sensors are the backbone of many imaging technologies of great importance to modern sciences, being particularly relevant in biomedicine. An ideal image sensor should be usable through all the electromagnetic spectrum (large…

Medical Physics · Physics 2022-03-16 Juan Aguirre

An electron-tracking Compton camera (ETCC) is a detector that can determine the arrival direction and energy of incident sub-MeV/MeV gamma-ray events on an event-by-event basis. It is a hybrid detector consisting of a gaseous time…

We report the direct detection of gamma-ray emission from the Galactic center in the 150-600 keV band using the electron-tracking Compton camera (ETCC), which has a wide field of view of 3.1 sr. This represents the first application of this…

High Energy Astrophysical Phenomena · Physics 2026-05-12 Tomonori Ikeda , Toru Tanimori , Atsushi Takada , Taito Takemura , Kei Yoshikawa , Yuta Nakamura , Ken Onozaka , Mitsuru Abe , Yoshitaka Mizumura
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