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Phylogenetic analyses of gene expression have great potential for addressing a wide range of questions. These analyses will, for example, identify genes that have evolutionary shifts in expression that are correlated with evolutionary…

Populations and Evolution · Quantitative Biology 2014-01-14 Casey W. Dunn , Xi Luo , Zhijin Wu

Statistical consistency in phylogenetics has traditionally referred to the accuracy of estimating phylogenetic parameters for a fixed number of species as we increase the number of characters. However, as sequences are often of fixed length…

Populations and Evolution · Quantitative Biology 2010-04-09 Olivier Gascuel , Mike Steel

Phylogenetic trees canonically arise as embeddings of phylogenetic networks. We recently showed that the problem of deciding if two phylogenetic networks embed the same sets of phylogenetic trees is computationally hard, \blue{in…

Combinatorics · Mathematics 2021-04-13 Janosch Doecker , Simone Linz , Charles Semple

A geophylogeny is a phylogenetic tree (or dendrogram) where each leaf (e.g. biological taxon) has an associated geographic location (site). To clearly visualize a geophylogeny, the tree is typically represented as a crossing-free drawing…

Discrete Mathematics · Computer Science 2025-04-16 Jonathan Klawitter , Felix Klesen , Joris Y. Scholl , Thomas C. van Dijk , Alexander Zaft

Given a classification model and a prediction for some input, there are heuristic strategies for ranking features according to their importance in regard to the prediction. One common approach to this task is rooted in propositional logic…

Artificial Intelligence · Computer Science 2025-05-16 Tomás Capdevielle , Santiago Cifuentes

We present a formulation of the problem of probabilistic model checking as one of query evaluation over probabilistic logic programs. To the best of our knowledge, our formulation is the first of its kind, and it covers a rich class of…

Logic in Computer Science · Computer Science 2012-04-24 Andrey Gorlin , C. R. Ramakrishnan , Scott A. Smolka

We find surprisingly simple formulas for the limiting probability that the rank of a randomly selected vertex in a randomly selected phylogenetic tree or generalized phylogenetic tree is a given integer.

Combinatorics · Mathematics 2023-06-22 Miklós Bóna

In medical imaging, particularly in early disease detection and prognosis tasks, discerning the rationale behind an AI model's predictions is crucial for evaluating the reliability of its decisions. Conventional explanation methods face…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Yingying Fang , Zihao Jin , Xiaodan Xing , Simon Walsh , Guang Yang

Combining a set of phylogenetic trees into a single phylogenetic network that explains all of them is a fundamental challenge in evolutionary studies. Existing methods are computationally expensive and can either handle only small numbers…

Populations and Evolution · Quantitative Biology 2023-04-07 Giulia Bernardini , Leo van Iersel , Esther Julien , Leen Stougie

In phylogenetics, a central problem is to infer the evolutionary relationships between a set of species $X$; these relationships are often depicted via a phylogenetic tree -- a tree having its leaves univocally labeled by elements of $X$…

Data Structures and Algorithms · Computer Science 2016-04-12 Julien Baste , Christophe Paul , Ignasi Sau , Celine Scornavacca

Understanding the evolution of a set of genes or species is a fundamental problem in evolutionary biology. The problem we study here takes as input a set of trees describing {possibly discordant} evolutionary scenarios for a given set of…

Data Structures and Algorithms · Computer Science 2019-07-10 Cedric Chauve , Mark Jones , Manuel Lafond , Céline Scornavacca , Mathias Weller

In classification and forecasting with tabular data, one often utilizes tree-based models. Those can be competitive with deep neural networks on tabular data and, under some conditions, explainable. The explainability depends on the depth…

Machine Learning · Computer Science 2024-06-05 Jiri Nemecek , Tomas Pevny , Jakub Marecek

During the last decade, deep neural networks (DNN) have demonstrated impressive performances solving a wide range of problems in various domains such as medicine, finance, law, etc. Despite their great performances, they have long been…

Machine Learning · Computer Science 2020-10-13 Jiechieu Kameni Florentin Flambeau , Tsopze Norbert

We survey the problem of deciding the stability or stabilizability of uncertain linear systems whose region of uncertainty is a polytope. This natural setting has applications in many fields of applied science, from Control Theory to…

Systems and Control · Computer Science 2014-02-12 Nikos Vlassis , Raphaël Jungers

Phylogenetic trees are simple models of evolutionary processes. They describe conditionally independent divergent evolution of taxa from common ancestors. Phylogenetic trees commonly do not have enough flexibility to adequately model all…

Populations and Evolution · Quantitative Biology 2025-11-11 Jonathan D. Mitchell , Barbara R. Holland

Local explanation frameworks aim to rationalize particular decisions made by a black-box prediction model. Existing techniques are often restricted to a specific type of predictor or based on input saliency, which may be undesirably…

Machine Learning · Computer Science 2019-02-12 Brandon Carter , Jonas Mueller , Siddhartha Jain , David Gifford

One challenge in fact checking is the ability to improve the transparency of the decision. We present a fact checking method that uses reference information in knowledge graphs (KGs) to assess claims and explain its decisions. KGs contain a…

Databases · Computer Science 2019-06-24 Naser Ahmadi , Joohyung Lee , Paolo Papotti , Mohammed Saeed

Some genes can change their relative locations in a genome. Thus for different individuals of the same species, the orders of genes might be different. Such jumping genes are called transposons. A practical problem is to determine…

Genomics · Quantitative Biology 2022-09-02 Yue Wang

Over the past 30 years numerous algorithms have been designed for symmetry breaking problems in the LOCAL model, such as maximal matching, MIS, vertex coloring, and edge-coloring. For most problems the best randomized algorithm is at least…

Computational Complexity · Computer Science 2016-04-07 Yi-Jun Chang , Tsvi Kopelowitz , Seth Pettie

Models like support vector machines or Gaussian process regression often require positive semi-definite kernels. These kernels may be based on distance functions. While definiteness is proven for common distances and kernels, a proof for a…

Machine Learning · Computer Science 2018-07-11 Martin Zaefferer , Thomas Bartz-Beielstein , Günter Rudolph