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In observational astronomy, noise obscures signals of interest. Large-scale astronomical surveys are growing in size and complexity, which will produce more data and increase the workload of data processing. Developing automated tools, such…

Instrumentation and Methods for Astrophysics · Physics 2022-09-16 Yunchong Zhang , Brian Nord , Amanda Pagul , Michael Lepori

Low-light, long-exposure defocus deblurring remains a challenging problem due to the simultaneous presence of severe blur and complex biased noise. Existing methods typically rely on simplified noise assumptions, which limits their…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Ziyan Huang , Lang Wu , Hongji Wang , Yifei Liu , Dongliang Tang , Hongqiao Wang

In image denoising problems, one widely-adopted approach is to minimize a regularized data-fit objective function, where the data-fit term is derived from a physical image acquisition model. Typically the regularizer is selected with two…

Optimization and Control · Mathematics 2015-08-13 Albert Oh , Rebecca Willett

We propose a general framework for solving inverse problems in the presence of noise that requires no signal prior, no noise estimate, and no clean training data. We only require that the forward model be available and that the noise be…

Computer Vision and Pattern Recognition · Computer Science 2020-06-12 Hirofumi Kobayashi , Ahmet Can Solak , Joshua Batson , Loic A. Royer

Microscopy image analysis often requires the segmentation of objects, but training data for this task is typically scarce and hard to obtain. Here we propose DenoiSeg, a new method that can be trained end-to-end on only a few annotated…

Computer Vision and Pattern Recognition · Computer Science 2020-06-12 Tim-Oliver Buchholz , Mangal Prakash , Alexander Krull , Florian Jug

Although the advances of self-supervised blind denoising are significantly superior to conventional approaches without clean supervision in synthetic noise scenarios, it shows poor quality in real-world images due to spatially correlated…

Computer Vision and Pattern Recognition · Computer Science 2023-02-22 Kanggeun Lee , Kyungryun Lee , Won-Ki Jeong

The term blind denoising refers to the fact that the basis used for denoising is learnt from the noisy sample itself during denoising. Dictionary learning and transform learning based formulations for blind denoising are well known. But…

Signal Processing · Electrical Eng. & Systems 2019-12-17 Angshul Majumdar

Ultrafast electron beam X-ray computed tomography produces noisy data due to short measurement times, causing reconstruction artifacts and limiting overall image quality. To counteract these issues, two self-supervised deep learning methods…

Machine Learning · Computer Science 2025-11-24 Israt Jahan Tulin , Sebastian Starke , Dominic Windisch , André Bieberle , Peter Steinbach

Diffusion magnetic resonance imaging (dMRI) plays a vital role in both clinical diagnostics and neuroscience research. However, its inherently low signal-to-noise ratio (SNR), especially under high diffusion weighting, significantly…

Quantitative Methods · Quantitative Biology 2026-02-27 Jine Xie , Zhicheng Zhang , Yunwei Chen , Yanqiu Feng , Xinyuan Zhang

Most of previous image denoising methods focus on additive white Gaussian noise (AWGN). However,the real-world noisy image denoising problem with the advancing of the computer vision techiniques. In order to promote the study on this…

Computer Vision and Pattern Recognition · Computer Science 2018-04-11 Jun Xu , Hui Li , Zhetong Liang , David Zhang , Lei Zhang

Self-supervised image denoising implies restoring the signal from a noisy image without access to the ground truth. State-of-the-art solutions for this task rely on predicting masked pixels with a fully-convolutional neural network. This…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Mikhail Papkov , Pavel Chizhov , Leopold Parts

In machine learning approach to image denoising a network is trained to recover a clean image from a noisy one. In this paper a novel structure is proposed based on training multiple specialized networks as opposed to existing structures…

Image and Video Processing · Electrical Eng. & Systems 2020-12-01 Seyed Mohsen Hosseini

Though achieving excellent performance in some cases, current unsupervised learning methods for single image denoising usually have constraints in applications. In this paper, we propose a new approach which is more general and applicable…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Yutong Xie , Mingze Yuan , Bin Dong , Quanzheng Li

Deep neural networks provide state-of-the-art performance for image denoising, where the goal is to recover a near noise-free image from a noisy observation. The underlying principle is that neural networks trained on large datasets have…

Information Theory · Computer Science 2019-04-09 Reinhard Heckel , Wen Huang , Paul Hand , Vladislav Voroninski

Deep neural networks have been proved efficient for medical image denoising. Current training methods require both noisy and clean images. However, clean images cannot be acquired for many practical medical applications due to naturally…

Image and Video Processing · Electrical Eng. & Systems 2019-06-11 Dufan Wu , Kuang Gong , Kyungsang Kim , Quanzheng Li

In this work, we present Blind-Spot Guided Diffusion, a novel self-supervised framework for real-world image denoising. Our approach addresses two major challenges: the limitations of blind-spot networks (BSNs), which often sacrifice local…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Shen Cheng , Haipeng Li , Haibin Huang , Xiaohong Liu , Shuaicheng Liu

We propose an effective deep learning model for signal reconstruction, which requires no signal prior, no noise model calibration, and no clean samples. This model only assumes that the noise is independent of the measurement and that the…

Computer Vision and Pattern Recognition · Computer Science 2021-10-27 Feng Wang , Trond R. Henninen , Debora Keller , Rolf Erni

Supervised training of deep neural networks on pairs of clean image and noisy measurement achieves state-of-the-art performance for many image reconstruction tasks, but such training pairs are difficult to collect. Self-supervised methods…

Image and Video Processing · Electrical Eng. & Systems 2023-10-30 Tobit Klug , Dogukan Atik , Reinhard Heckel

The success of deep denoisers on real-world color photographs usually relies on the modeling of sensor noise and in-camera signal processing (ISP) pipeline. Performance drop will inevitably happen when the sensor and ISP pipeline of test…

Computer Vision and Pattern Recognition · Computer Science 2021-03-19 Yue Cao , Xiaohe Wu , Shuran Qi , Xiao Liu , Zhongqin Wu , Wangmeng Zuo

Self-Supervised Learning (SSL) has become a powerful solution to extract rich representations from unlabeled data. Yet, SSL research is mostly focused on clean, curated and high-quality datasets. As a result, applying SSL on noisy data…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Wenquan Lu , Jiaqi Zhang , Hugues Van Assel , Randall Balestriero