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The human brain is a complex system defined by multi-way, higher-order interactions invisible to traditional pairwise network models. Although a diverse array of analytical methods has been developed to address this shortcoming, the field…

Quantitative Methods · Quantitative Biology 2025-11-11 Mohamma Reza Salehi , Ali BashirGonbadi , Hamid Soltanian-Zadeh

Despite the excitement behind biomedical artificial intelligence (AI), access to high-quality, diverse, and large-scale data - the foundation for modern AI systems - is still a bottleneck to unlocking its full potential. To address this…

The relation between large-scale brain structure and function is an outstanding open problem in neuroscience. We approach this problem by studying the dynamical regime under which realistic spatio-temporal patterns of brain activity emerge…

Neurons and Cognition · Quantitative Biology 2014-05-27 Ariel Haimovici , Enzo Tagliazucchi , Pablo Balenzuela , Dante R. Chialvo

Recent studies have shown that multi-modeling methods can provide new insights into the analysis of brain components that are not possible when each modality is acquired separately. The joint representations of different modalities is a…

Neurons and Cognition · Quantitative Biology 2022-01-24 Jalal Mirakhorli

The central nervous system is composed of many individual units -- from cells to areas -- that are connected with one another in a complex pattern of functional interactions that supports perception, action, and cognition. One natural and…

Neurons and Cognition · Quantitative Biology 2017-04-03 Ann E. Sizemore , Danielle S. Bassett

As very large studies of complex neuroimaging phenotypes become more common, human quality assessment of MRI-derived data remains one of the last major bottlenecks. Few attempts have so far been made to address this issue with machine…

Two major initiatives to accelerate research in the brain sciences have focused attention on developing a new generation of scientific instruments for neuroscience. These instruments will be used to record static (structural) and dynamic…

Neurons and Cognition · Quantitative Biology 2013-07-30 Thomas Dean , Biafra Ahanonu , Mainak Chowdhury , Anjali Datta , Andre Esteva , Daniel Eth , Nobie Redmon , Oleg Rumyantsev , Ysis Tarter

Thinking is one of the most interesting mental processes. Its complexity is sometimes simplified and its different manifestations are classified into normal and abnormal, like the delusional and disorganized thought or the creative one. The…

Neural and Evolutionary Computing · Computer Science 2007-05-23 Daniele Quintella Mendes , Luis Alfredo Vidal de Carvalho

Neuroimaging datasets keep growing in size to address increasingly complex medical questions. However, even the largest datasets today alone are too small for training complex models or for finding genome wide associations. A solution is to…

Computer Vision and Pattern Recognition · Computer Science 2018-05-01 Christian Wachinger , Benjamin Gutierrez Becker , Anna Rieckmann

The integration of diverse clinical modalities such as medical imaging and the tabular data extracted from patients' Electronic Health Records (EHRs) is a crucial aspect of modern healthcare. Integrative analysis of multiple sources can…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Daniel Duenias , Brennan Nichyporuk , Tal Arbel , Tammy Riklin Raviv

There are multiple scales of abstraction from which we can describe the same image, depending on whether we are focusing on fine-grained details or a more global attribute of the image. In brain mapping, learning to automatically parse…

Despite the impressive advances achieved using deep learning for functional brain activity analysis, the heterogeneity of functional patterns and the scarcity of imaging data still pose challenges in tasks such as identifying neurological…

Image and Video Processing · Electrical Eng. & Systems 2025-05-30 Wenhui Cui , Haleh Akrami , Anand A. Joshi , Richard M. Leahy

Functional networks representing human brain dynamics have become a standard tool in neuroscience, providing an accessible way of depicting the computation performed by the brain in healthy and pathological conditions. Yet, these networks…

Neurons and Cognition · Quantitative Biology 2025-05-26 Sofia Gil-Rodrigo , Raúl López-Martín , Görsev Yener , Jan R. Wiersema , Bahar Güntekin , Massimiliano Zanin

Diseases involve complex processes and modifications to the cellular machinery. The gene expression profile of the affected cells contains characteristic patterns linked to a disease. Hence, biological knowledge pertaining to a disease can…

Quantitative Methods · Quantitative Biology 2020-04-13 Thomas Gaudelet , Noel Malod-Dognin , Jon Sanchez-Valle , Vera Pancaldi , Alfonso Valencia , Natasa Przulj

A major challenge in both neuroscience and machine learning is the development of useful tools for understanding complex information processing systems. One such tool is probes, i.e., supervised models that relate features of interest to…

Machine Learning · Computer Science 2021-04-19 Anna A. Ivanova , John Hewitt , Noga Zaslavsky

Meta-learning aims to develop algorithms that can learn from other learning algorithms to adapt to new and changing environments. This requires a model of how other learning algorithms operate and perform in different contexts, which is…

Machine Learning · Computer Science 2023-05-23 Yuwei Sun

By promising more accurate diagnostics and individual treatment recommendations, deep neural networks and in particular convolutional neural networks have advanced to a powerful tool in medical imaging. Here, we first give an introduction…

Machine Learning · Computer Science 2023-01-23 Fabian Eitel , Marc-André Schulz , Moritz Seiler , Henrik Walter , Kerstin Ritter

Imaging methods used in modern neuroscience experiments are quickly producing large amounts of data capable of providing increasing amounts of knowledge about neuroanatomy and function. A great deal of information in these datasets is…

Quantitative Methods · Quantitative Biology 2017-01-25 William Gray Roncal , Eva L Dyer , Doga Gürsoy , Konrad Kording , Narayanan Kasthuri

Reading comprehension is a challenging task, especially when executed across longer or across multiple evidence documents, where the answer is likely to reoccur. Existing neural architectures typically do not scale to the entire evidence,…

Computation and Language · Computer Science 2018-06-01 Swabha Swayamdipta , Ankur P. Parikh , Tom Kwiatkowski

Artificial Intelligence has emerged as a useful aid in numerous clinical applications for diagnosis and treatment decisions. Deep neural networks have shown same or better performance than clinicians in many tasks owing to the rapid…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Zohaib Salahuddin , Henry C Woodruff , Avishek Chatterjee , Philippe Lambin