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The shape that stem cells reach at the end of adhesion process influences their differentiation. Rearrangement of cytoskeleton and modification of intracellular tension may activate mechanotransduction pathways controlling cell commitment.…

Recent developments in lipid membrane models for simulations are reviewed. To reduce computational costs, various coarse-grained molecular models have been proposed. Among them, implicit solvent (solvent-free) molecular models are…

Soft Condensed Matter · Physics 2015-05-13 Hiroshi Noguchi

This study presents an innovative computer vision framework designed to analyze human movements in industrial settings, aiming to enhance biomechanical analysis by integrating seamlessly with existing software. Through a combination of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Jesudara Omidokun , Darlington Egeonu , Bochen Jia , Liang Yang

The mechanical properties of human soft tissue are crucial for impact biomechanics, rehabilitation engineering and surgical simulation. Validation of these constitutive models using human data remains challenging and often requires the use…

Medical Physics · Physics 2016-04-25 Kevin M. Moerman , Cathy A. Holt , Sam L. Evans , Ciaran K. Simms

Multi-modal MRIs are widely used in neuroimaging applications since different MR sequences provide complementary information about brain structures. Recent works have suggested that multi-modal deep learning analysis can benefit from…

Computer Vision and Pattern Recognition · Computer Science 2021-06-14 Jiahong Ouyang , Ehsan Adeli , Kilian M. Pohl , Qingyu Zhao , Greg Zaharchuk

In the 80's, biomechanicians were asked to work on Computer Aided Surgery applications since orthopaedic surgeons were looking for numerical tools able to predict risks of fractures. More recently, biomechanicians started to address soft…

Medical Physics · Physics 2007-09-03 Patrick Schiavone , T. Boudou , J. Ohayon , Y. Payan

Coarse-grained, mesoscale simulations are invaluable for studying soft condensed matter because of their ability to model systems in which a background solvent plays a significant role but is not the primary interest. Such methods generally…

Soft Condensed Matter · Physics 2024-03-19 Timofey Kozhukhov , Tyler N. Shendruk

We present a deep learning model to automatically generate computer models of the human heart from patient imaging data with an emphasis on its capability to generate thin-walled cardiac structures. Our method works by deforming a template…

Computer Vision and Pattern Recognition · Computer Science 2024-01-05 Arjun Narayanan , Fanwei Kong , Shawn Shadden

Lipid membranes and membrane deformations are a long-standing area of research in soft matter and biophysics. Computer simulations have complemented analytical and experimental approaches as one of the pillars in the field. However, setting…

Soft tissues - such as ligaments and tendons - primarily consist of solid (collagen, predominantly) and liquid phases. Understanding the interaction between such components and how they change under physiological loading sets the basis for…

We present a tactile sensing method enabled by the mechanical compliance of soft robots; an externally attachable photoreflective module reads surface deformation of silicone skin to estimate contact force without embedding tactile…

This scientific paper explores two distinct approaches for identifying and approximating the simulation model, particularly in the context of the snap process crucial to medical device assembly. Simulation models play a pivotal role in…

Machine Learning · Computer Science 2023-09-27 Fatemeh Kakavandi

A number of recent studies have focused on developing surgical simulation platforms to train machine learning (ML) agents or models with synthetic data for surgical assistance. While existing platforms excel at tasks such as rigid body…

Robotics · Computer Science 2025-07-04 Yafei Ou , Mahdi Tavakoli

Tools, models and statistical methods for signal processing and medical image analysis and training deep learning models to create research prototypes for eventual clinical applications are of special interest to the biomedical imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-12-22 Pratik Shah , Jenna Lester , Jana G Deflino , Vinay Pai

This second part of paper develops a theory of linear viscoelastic nematodynamics applicable to LCP. The viscous and elastic nematic components in theory are described by using the LEP approach for viscous nematics and de Gennes free energy…

Soft Condensed Matter · Physics 2007-05-23 Arkady I. Leonov

The finite element method (FEM) is among the most commonly used numerical methods for solving engineering problems. Due to its computational cost, various ideas have been introduced to reduce computation times, such as domain decomposition,…

Computational Engineering, Finance, and Science · Computer Science 2019-11-07 Andrea Mendizabal , Pablo Márquez-Neila , Stéphane Cotin

This work outlines a new multi-physics-compatible immersed rigid body method for Eulerian finite-volume simulations. To achieve this, rigid bodies are represented as a diffuse scalar field and an interface seeding method is employed to…

Computational Physics · Physics 2022-03-15 Tim Wallis , Philip Barton , Nikolaos Nikiforakis

The formation of shear shock waves in the brain has been proposed as one of the plausible explanations for deep intracranial injuries. In fact, such singular solutions emerge naturally in soft viscoelastic tissues under dynamic loading…

Soft Condensed Matter · Physics 2025-02-05 Harold Berjamin

Numerical and analytical methods are developed for the investigation of contact sets in electrostatic-elastic deflections modeling micro-electro mechanical systems. The model for the membrane deflection is a fourth-order semi-linear partial…

Numerical Analysis · Mathematics 2020-04-20 Kelsey L. DiPietro , Ronald D. Haynes , Weizhang Huang , Alan E. Lindsay , Yufei Yu

In this work a finite element simulation of the motion of a rigid body in a fluid, with free surface, is described. A completely general referential description (of which both Lagrangian and Eulerian descriptions are special cases) of an…

Fluid Dynamics · Physics 2015-06-26 S. J. Childs , B. D. Reddy