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Current models on Explainable Artificial Intelligence (XAI) have shown an evident and quantified lack of reliability for measuring feature-relevance when statistically entangled features are proposed for training deep classifiers. There has…

Signal Processing · Electrical Eng. & Systems 2023-02-27 Juan Manuel Mayor-Torres , Sara Medina-DeVilliers , Tessa Clarkson , Matthew D. Lerner , Giuseppe Riccardi

Depression is a common yet serious mental disorder that affects millions of U.S. high schoolers every year. Still, accurate diagnosis and early detection remain significant challenges. In the field of public health, research shows that…

Machine Learning · Computer Science 2023-08-23 Nathan Zhong , Nikhil Yadav

Brain tumors remain a critical global health challenge, necessitating advancements in diagnostic techniques and treatment methodologies. A tumor or its recurrence often needs to be identified in imaging studies and differentiated from…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Shashidhar Reddy Javaji , Sovesh Mohapatra , Advait Gosai , Gottfried Schlaug

We propose a novel optimization framework to predict clinical severity from resting state fMRI (rs-fMRI) data. Our model consists of two coupled terms. The first term decomposes the correlation matrices into a sparse set of representative…

Neurons and Cognition · Quantitative Biology 2024-11-25 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart H. Mostofsky , Archana Venkataraman

We present an approach to model time series data from resting state fMRI for autism spectrum disorder (ASD) severity classification. We propose to adopt kernel machines and employ graph kernels that define a kernel dot product between two…

Machine Learning · Statistics 2016-12-04 Rushil Anirudh , Jayaraman J. Thiagarajan , Irene Kim , Wolfgang Polonik

Understanding how large-scale functional brain networks reorganize during cognitive decline remains a central challenge in neuroimaging. While recent self-supervised models have shown promise for learning representations from resting-state…

Machine Learning · Computer Science 2026-03-03 Karanpartap Singh , Adam Turnbull , Mohammad Abbasi , Kilian Pohl , Feng Vankee Lin , Ehsan Adeli

Decoding cognitive states from functional magnetic resonance imaging is central to understanding the functional organization of the brain. Within-subject decoding avoids between-subject correspondence problems but requires large sample…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Himanshu Aggarwal , Liza Al-Shikhley , Bertrand Thirion

An ensemble of classifiers combines several single classifiers to deliver a final prediction or classification decision. An increasingly provoking question is whether such systems can outperform the single best classifier. If so, what form…

Machine Learning · Computer Science 2022-09-07 Bhekisipho Twala , Eamon Molloy

Deep unsupervised representation learning has recently led to new approaches in the field of Unsupervised Anomaly Detection (UAD) in brain MRI. The main principle behind these works is to learn a model of normal anatomy by learning to…

Image and Video Processing · Electrical Eng. & Systems 2020-04-09 Christoph Baur , Stefan Denner , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

Radiomics with deep learning models have become popular in computer-aided diagnosis and have outperformed human experts on many clinical tasks. Specifically, radiomic models based on artificial intelligence (AI) are using medical data…

Image and Video Processing · Electrical Eng. & Systems 2022-06-08 Ahmad Chaddad , Jiali li , Qizong Lu , Yujie Li , Idowu Paul Okuwobi , Camel Tanougast , Christian Desrosiers , Tamim Niazi

Functional Magnetic Resonance Imaging (fMRI) provides useful insights into the brain function both during task or rest. Representing fMRI data using correlation matrices is found to be a reliable method of analyzing the inherent…

Machine Learning · Computer Science 2025-01-29 Yicheng Leng , Syed Muhammad Anwar , Islem Rekik , Sen He , Eung-Joo Lee

Accurate diagnosis of Autism Spectrum Disorder (ASD) followed by effective rehabilitation is essential for the management of this disorder. Artificial intelligence (AI) techniques can aid physicians to apply automatic diagnosis and…

Resting-state functional Magnetic Resonance Imaging (R-fMRI) holds the promise to reveal functional biomarkers of neuropsychiatric disorders. However, extracting such biomarkers is challenging for complex multi-faceted neuropatholo-gies,…

Accurate diagnosis of autism spectrum disorder (ASD) based on neuroimaging data has significant implications, as extracting useful information from neuroimaging data for ASD detection is challenging. Even though machine learning techniques…

Machine Learning · Computer Science 2022-06-13 Ruimin Ma , Yanlin Wang , Yanjie Wei , Yi Pan

Deep learning and contactless sensing technologies have significantly advanced the automated assessment of human behaviors in healthcare. In the context of autism spectrum disorder (ASD), repetitive motor behaviors such as spinning, head…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Amit Kumar Singh , Vrijendra Singh

Precise breast cancer classification on histopathological images has the potential to greatly improve the diagnosis and patient outcome in oncology. The data imbalance problem largely stems from the inherent imbalance within medical image…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Majid Behzadpour , Bengie L. Ortiz , Ebrahim Azizi , Kai Wu

Alzheimer's Disease (AD) is the world leading cause of dementia, a progressively impairing condition leading to high hospitalization rates and mortality. To optimize the diagnostic process, numerous efforts have been directed towards the…

Image and Video Processing · Electrical Eng. & Systems 2025-01-20 Davide Coluzzi , Valentina Bordin , Massimo Walter Rivolta , Igor Fortel , Liang Zhang , Alex Leow , Giuseppe Baselli

Traditional causal connectivity methods in task-based and resting-state functional magnetic resonance imaging (fMRI) face challenges in accurately capturing directed information flow due to their sensitivity to noise and inability to model…

Neurons and Cognition · Quantitative Biology 2025-04-03 Boseong Kim , Debashis Das Chakladar , Haejun Chung , Ikbeom Jang

Deep learning models can enable accurate and efficient disease diagnosis, but have thus far been hampered by the data scarcity present in the medical world. Automated diagnosis studies have been constrained by underpowered single-center…

Image and Video Processing · Electrical Eng. & Systems 2022-03-04 Akis Linardos , Kaisar Kushibar , Sean Walsh , Polyxeni Gkontra , Karim Lekadir

Caregivers of individuals with autism spectrum disorder (ASD) often find the 77-item Autism Treatment Evaluation Checklist (ATEC) burdensome, limiting its use for routine monitoring. This study introduces a generalizable machine learning…

Applications · Statistics 2025-11-03 Audrey Dong , Claire Xu , Samuel R. Guo , Kevin Yang , Xue-Jun Kong