Related papers: Spinning Disk -- Remote Focusing Microscopy
Significance: Access to diagnostic eye care could be expanded with high-throughput and easy-to-use tools. Phase mask-based imaging may improve the fundus camera by enabling computational refocusing with no moving parts. While phase…
Background: Accurate spinal structure measurement is crucial for assessing spine health and diagnosing conditions like spondylosis, disc herniation, and stenosis. Manual methods for measuring intervertebral disc height and spinal canal…
The high prevalence of spinal stenosis results in a large volume of MRI imaging, yet interpretation can be time-consuming with high inter-reader variability even among the most specialized radiologists. In this paper, we develop an…
Aberration-corrected scanning transmission electron microscopes (STEM) provide sub-angstrom lateral resolution; however, the large convergence angle greatly reduces the depth of field. For microscopes with a small depth of field,…
A number of questions in systems biology such as understanding how dynamics of neuronal networks are related to brain function require the ability to capture the functional dynamics of large cellular populations at high speed. Recently,…
A method for estimating the axis of reflectional symmetry of an image $f(x,y)$ on the unit disc $D=\{(x,y):x^2+y^2\leq1\}$ is proposed, given that noisy data of $f(x,y)$ are observed on a discrete grid of edge width $\Delta$. Our estimation…
Fluorescence lifetime imaging microscopy (FLIM) systems are limited by their slow processing speed, low signal-to-noise ratio (SNR), and expensive and challenging hardware setups. In this work, we demonstrate applying a denoising…
We experimentally demonstrate that a Duraluminium thin plate with a thickness profile varying radially in a piecewise constant fashion as h(r)=h(0)(1+(r/Rmax)), with h(0)=0.5 mm, h(Rmax)=2 mm and Rmax=10 cm behaves in many ways as Maxwell's…
Autofocus (AF) methods are extensively used in biomicroscopy, for example to acquire timelapses, where the imaged objects tend to drift out of focus. AD algorithms determine an optimal distance by which to move the sample back into the…
Moving objects leave extended tracks in optical images acquired with a telescope that is tracking stars or other targets. By searching images for these tracks, one can obtain statistics on populations of space debris in Earth orbit. The…
Purpose: To develop an automatic method of quantifying optic disc pallor in fundus photographs and determine associations with peripapillary retinal nerve fibre layer (pRNFL) thickness. Methods: We used deep learning to segment the optic…
Acquiring high-contrast optical images deep inside biological tissues is still a challenging problem. Confocal microscopy is an important tool for biomedical imaging since it improves image quality by rejecting background signals. However,…
Hyperspectral imaging is a cutting-edge type of remote sensing used for mapping vegetation properties, rock minerals and other materials. A major drawback of hyperspectral imaging devices is their intrinsic low spatial resolution. In this…
Ring-core optical fibers have been designed to carry orbital angular momentum modes. We demonstrate the imaging of these modes, individually identifying modes separated temporally by only 30~ps. A single-pixel camera operating in the…
We extend our previously proposed image reconstruction method, which allows confocal microscopes to capture periodically moving objects at frequencies beyond their frame rates, to three-dimensional and two-dimensional wide-field imaging.…
The clinical treatment of degenerative and developmental lumbar spinal stenosis (LSS) is different. Computed tomography (CT) is helpful in distinguishing degenerative and developmental LSS due to its advantage in imaging of osseous and…
Diffusion MRI microstructure fitting is nonconvex and often performed voxelwise, which limits fiber peak recovery in narrow crossings. This work introduces PRISM, a differentiable analysis-by-synthesis framework that fits an explicit…
Whole slide imaging (WSI) has recently been cleared for primary diagnosis in the US. A critical challenge of WSI is to perform accurate focusing in high speed. Traditional systems create a focus map prior to scanning. For each focus point…
Lumbar disk segmentation is essential for diagnosing and curing spinal disorders by enabling precise detection of disk boundaries in medical imaging. The advent of deep learning has resulted in the development of many segmentation methods,…
The primary function of intestinal microvilli is to increase the surface area of the intestinal lining to maximize nutrient absorption. This is especially important as fish, like other animals, need to efficiently absorb proteins,…