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Automated diagnosis based on color fundus photography is essential for large-scale glaucoma screening. However, existing deep learning models are typically data-driven and lack explicit integration of retinal anatomical knowledge, which…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Yuzhuo Zhou , Chi Liu , Sheng Shen , Zongyuan Ge , Fengshi Jing , Shiran Zhang , Yu Jiang , Anli Wang , Wenjian Liu , Feilong Yang , Tianqing Zhu , Xiaotong Han

Automated optic disc (OD) and optic cup (OC) segmentation in fundus images is relevant to efficiently measure the vertical cup-to-disc ratio (vCDR), a biomarker commonly used in ophthalmology to determine the degree of glaucomatous optic…

This work aims to research an automatic method for detecting Age-related Macular Degeneration (AMD) lesions in RGB eye fundus images. For this, we align invasively obtained eye fundus contrast images (the "golden standard" diagnostic) to…

Image and Video Processing · Electrical Eng. & Systems 2021-10-19 Rokas Pečiulis , Mantas Lukoševičius , Algimantas Kriščiukaitis , Robertas Petrolis , Dovilė Buteikienė

The Segment Anything Model (SAM) has gained popularity as a versatile image segmentation method, thanks to its strong generalization capabilities across various domains. However, when applied to optic disc (OD) and optic cup (OC)…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Jinchen Yu , Yongwei Nie , Fei Qi , Wenxiong Liao , Hongmin Cai

Automated Computer Aided diagnostic tools can be used for the early detection of glaucoma to prevent irreversible vision loss. In this work, we present a Multi-task Convolutional Neural Network (CNN) that jointly segments the Optic Disc…

Computer Vision and Pattern Recognition · Computer Science 2018-08-07 Arunava Chakravarty , Jayanthi Sivswamy

Papilledema is an ophthalmic neurologic disorder in which increased intracranial pressure leads to swelling of the optic nerves. Undiagnosed papilledema in children may lead to blindness and may be a sign of life-threatening conditions,…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Kleanthis Avramidis , Mohammad Rostami , Melinda Chang , Shrikanth Narayanan

Glaucoma is a chronic eye disease that leads to irreversible vision loss. The cup to disc ratio (CDR) plays an important role in the screening and diagnosis of glaucoma. Thus, the accurate and automatic segmentation of optic disc (OD) and…

Computer Vision and Pattern Recognition · Computer Science 2018-02-13 Huazhu Fu , Jun Cheng , Yanwu Xu , Damon Wing Kee Wong , Jiang Liu , Xiaochun Cao

Vascular structures in the retina contain important information for the detection and analysis of ocular diseases, including age-related macular degeneration, diabetic retinopathy and glaucoma. Commonly used modalities in diagnosis of these…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Erick O. Rodrigues , Aura Conci , Panos Liatsis

The hemorrhagic lesion segmentation plays a critical role in ophthalmic diagnosis, directly influencing early disease detection, treatment planning, and therapeutic efficacy evaluation. However, the task faces significant challenges due to…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Zesheng Li , Minwen Liao , Haoran Chen , Yan Su , Chengchang Pan , Honggang Qi

Our objective is to evaluate the efficacy of methods that use deep learning (DL) for the automatic fine-grained segmentation of optical coherence tomography (OCT) images of the retina. OCT images from 10 patients with mild non-proliferative…

Computer Vision and Pattern Recognition · Computer Science 2018-01-31 Mike Pekala , Neil Joshi , David E. Freund , Neil M. Bressler , Delia Cabrera DeBuc , Philippe M Burlina

Microaneurysms (MAs) are one of the earliest signs of diabetic retinopathy (DR), a frequent complication of diabetes that can lead to visual impairment and blindness. Adaptive optics scanning laser ophthalmoscopy (AOSLO) provides real-time…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Qian Zhang , Konstantina Sampani , Mengjia Xu , Shengze Cai , Yixiang Deng , He Li , Jennifer K. Sun , George Em Karniadakis

Optical coherence tomography (OCT) is a non-invasive imaging technique that can produce images of the eye at the microscopic level. OCT image segmentation to localise retinal layer boundaries is a fundamental procedure for diagnosing and…

Computer Vision and Pattern Recognition · Computer Science 2016-09-09 Jinming Duan , Christopher Tench , Irene Gottlob , Frank Proudlock , Li Bai

Projection map (PM) from optical coherence tomography (OCT) B-scan is an important tool to diagnose retinal diseases, which typically requires retinal layer segmentation. In this study, we present a novel end-to-end framework to predict PMs…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Dingyi Rong , Jiancheng Yang , Bingbing Ni , Bilian Ke

Diabetic retinopathy (DR) results in vision loss if not treated early. A computer-aided diagnosis (CAD) system based on retinal fundus images is an efficient and effective method for early DR diagnosis and assisting experts. A…

Computer Vision and Pattern Recognition · Computer Science 2019-08-23 Norah Asiri , Muhammad Hussain , Fadwa Al Adel , Nazih Alzaidi

The vascular structure of blood vessels is important in diagnosing retinal conditions such as glaucoma and diabetic retinopathy. Accurate segmentation of these vessels can help in detecting retinal objects such as the optic disc and optic…

Image and Video Processing · Electrical Eng. & Systems 2020-12-18 Abdullah Sarhan , Jon Rokne , Reda Alhajj , Andrew Crichton

Red-lesions, microaneurysms (MAs) and hemorrhages (HMs), are the early signs of diabetic retinopathy (DR). The automatic detection of MAs and HMs on retinal fundus images is a challenging task. Most of the existing methods detect either…

Image and Video Processing · Electrical Eng. & Systems 2025-05-02 Norah Asiri , Muhammad Hussain , Fadwa Al Adel

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

Automated segmentation of the optic cup and disk on retinal fundus images is fundamental for the automated detection / analysis of glaucoma. Traditional segmentation approaches depend heavily upon hand-crafted features and a priori…

Computer Vision and Pattern Recognition · Computer Science 2019-02-14 Lei Bi , Yuyu Guo , Qian Wang , Dagan Feng , Michael Fulham , Jinman Kim

Age-related macular degeneration (AMD) is one of the leading causes of irreversible vision impairment in people over the age of 60. This research focuses on semantic segmentation for AMD lesion detection in RGB fundus images, a non-invasive…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Valentyna Starodub , Mantas Lukoševičius

In this manuscript, we present a robust method for glaucoma screening from fundus images using an ensemble of convolutional neural networks (CNNs). The pipeline comprises of first segmenting the optic disk and optic cup from the fundus…

Computer Vision and Pattern Recognition · Computer Science 2018-09-17 Vismay Agrawal , Avinash Kori , Varghese Alex , Ganapathy Krishnamurthi