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Computational modeling is crucial for understanding and analyzing complex systems. In biology, model creation is a human dependent task that requires reading hundreds of papers and conducting wet lab experiments, which would take days or…

Quantitative Methods · Quantitative Biology 2021-10-22 Yasmine Ahmed , Natasa Miskov-Zivanov

The automated assembly and extension of dynamic network models using information extracted from literature are challenging due to the amount and inconsistency in published literature. Recently, efforts have been made to automatically and…

Molecular Networks · Quantitative Biology 2021-10-22 Yasmine Ahmed , Adam A Butchy , Khaled Sayed , Cheryl Telmer , Natasa Miskov-Zivanov

There is significant interest in using existing repositories of biological entities, relationships, and models to automate biological model assembly and extension. Current methods aggregate human-curated biological information into…

Molecular Networks · Quantitative Biology 2023-01-30 Adam A. Butchy , Cheryl A. Telmer , Natasa Miskov-Zivanov

Currently, data-driven discovery in biological sciences resides in finding segmentation strategies in multivariate data that produce sensible descriptions of the data. Clustering is but one of several approaches and sometimes falls short…

Quantitative Methods · Quantitative Biology 2022-08-12 Richard Tjörnhammar

Distributed model training suffers from communication bottlenecks due to frequent model updates transmitted across compute nodes. To alleviate these bottlenecks, practitioners use gradient compression techniques like sparsification,…

Machine Learning · Computer Science 2020-11-02 Saurabh Agarwal , Hongyi Wang , Kangwook Lee , Shivaram Venkataraman , Dimitris Papailiopoulos

Clustering is a widely-used data mining tool, which aims to discover partitions of similar items in data. We introduce a new clustering paradigm, \emph{accordant clustering}, which enables the discovery of (predefined) group level insights.…

Machine Learning · Computer Science 2017-04-11 Amit Dhurandhar , Margareta Ackerman , Xiang Wang

The alignment of biological sequences such as DNA, RNA, and proteins, is one of the basic tools that allow to detect evolutionary patterns, as well as functional/structural characterizations between homologous sequences in different…

Quantitative Methods · Quantitative Biology 2023-05-01 Louise Budzynski , Andrea Pagnani

Biological systems are often modelled at different levels of abstraction depending on the particular aims/resources of a study. Such different models often provide qualitatively concordant predictions over specific parametrisations, but it…

Machine Learning · Statistics 2016-05-10 Giulio Caravagna , Luca Bortolussi , Guido Sanguinetti

In recent years, the field of single-cell data analysis has seen a marked advancement in the development of clustering methods. Despite advancements, most of these algorithms still concentrate on analyzing the provided single-cell matrix…

Machine Learning · Computer Science 2023-12-18 Dayu Hu , Ke Liang , Hao Yu , Xinwang Liu

In correlation clustering, we are given $n$ objects together with a binary similarity score between each pair of them. The goal is to partition the objects into clusters so to minimise the disagreements with the scores. In this work we…

Machine Learning · Computer Science 2020-01-15 Marco Bressan , Nicolò Cesa-Bianchi , Andrea Paudice , Fabio Vitale

Abstraction is a fundamental part when learning behavioral models of systems. Usually the process of abstraction is manually defined by domain experts. This paper presents a method to perform automatic abstraction for network protocols. In…

Machine Learning · Computer Science 2018-06-05 Tobias Schrank , Franz Pernkopf

Clustering is an unsupervised machine learning methodology where unlabeled elements/objects are grouped together aiming to the construction of well-established clusters that their elements are classified according to their similarity. The…

Machine Learning · Statistics 2023-10-20 Dimitrios Saligkaras , Vasileios E. Papageorgiou

Correlation clustering is a flexible framework for partitioning data based solely on pairwise similarity or dissimilarity information, without requiring the number of clusters as input. However, in many practical scenarios, these pairwise…

Machine Learning · Computer Science 2025-12-11 Linus Aronsson , Morteza Haghir Chehreghani

Large Language Models (LLMs) have demonstrated impressive reasoning capabilities, yet their direct application to NP-hard combinatorial problems (CPs) remains underexplored. In this work, we systematically investigate the reasoning…

Machine Learning · Computer Science 2025-06-16 Henrik Abgaryan , Tristan Cazenave , Ararat Harutyunyan

Emotion recognition through artificial intelligence and smart sensing of physical and physiological signals (Affective Computing) is achieving very interesting results in terms of accuracy, inference times, and user-independent models. In…

Human-Computer Interaction · Computer Science 2024-10-08 Laura Gutierrez-Martin , Celia Lopez Ongil , Jose M. Lanza-Gutierrez , Jose A. Miranda Calero

While interpretability methods identify a model's learned concepts, they overlook the relationships between concepts that make up its abstractions and inform its ability to generalize to new data. To assess whether models' have learned…

Machine Learning · Computer Science 2025-11-04 Angie Boggust , Hyemin Bang , Hendrik Strobelt , Arvind Satyanarayan

1. Expert knowledge elicitation provides information to characterize ecological systems and management options. Linking expert knowledge elicitation with a curated question catalog supports a community of practice for ongoing improvement of…

A novel approach rooted on the notion of consensus clustering, a strategy developed for community detection in complex networks, is proposed to cope with the heterogeneity that characterizes connectivity matrices in health and disease. The…

Neurons and Cognition · Quantitative Biology 2017-05-09 Javier Rasero , Mario Pellicoro , Leonardo Angelini , Jesus M. Cortes , Daniele Marinazzo , Sebastiano Stramaglia

The availability of large data sets is providing an impetus for driving current artificial intelligent developments. There are, however, challenges for developing solutions with small data sets due to practical and cost-effective deployment…

Machine Learning · Computer Science 2024-05-17 Luca Gherardini , Varun Ravi Varma , Karol Capala , Roger Woods , Jose Sousa

Biomedical research results are being published at a high rate, and with existing search engines, the vast amount of published work is usually easily accessible. However, reproducing published results, either experimental data or…

Molecular Networks · Quantitative Biology 2017-06-19 Kai-Wen Liang , Qinsi Wang , Cheryl Telmer , Divyaa Ravichandran , Peter Spirtes , Natasa Miskov-Zivanov
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