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Hierarchical clustering is an effective, interpretable method for analyzing structure in data. It reveals insights at multiple scales without requiring a predefined number of clusters and captures nested patterns and subtle relationships,…

The clustering and visualisation of high-dimensional data is a ubiquitous task in modern data science. Popular techniques include nonlinear dimensionality reduction methods like t-SNE or UMAP. These methods face the `scale-problem' of…

Machine Learning · Statistics 2025-10-20 Jack Kendrick

This paper investigates the theoretical foundations of the t-distributed stochastic neighbor embedding (t-SNE) algorithm, a popular nonlinear dimension reduction and data visualization method. A novel theoretical framework for the analysis…

Machine Learning · Statistics 2022-11-02 T. Tony Cai , Rong Ma

Cluster visualization is an essential task for nonlinear dimensionality reduction as a data analysis tool. It is often believed that Student t-Distributed Stochastic Neighbor Embedding (t-SNE) can show clusters for well clusterable data,…

Machine Learning · Computer Science 2021-10-07 Zhirong Yang , Yuwei Chen , Jukka Corander

t-distributed Stochastic Neighborhood Embedding (t-SNE), a clustering and visualization method proposed by van der Maaten & Hinton in 2008, has rapidly become a standard tool in a number of natural sciences. Despite its overwhelming…

Machine Learning · Computer Science 2017-06-09 George C. Linderman , Stefan Steinerberger

$t$-SNE is an embedding method that the data science community has widely Two interesting characteristics of t-SNE are the structure preservation property and the answer to the crowding problem, where all neighbors in high dimensional space…

Machine Learning · Computer Science 2021-09-23 Gaëlle Candel , David Naccache

The recent advancements in computational power and machine learning algorithms have led to vast improvements in manifold areas of research. Especially in finance, the application of machine learning enables both researchers and…

Statistical Finance · Quantitative Finance 2020-05-21 Sven Husmann , Antoniya Shivarova , Rick Steinert

When visualizing a high-dimensional dataset, dimension reduction techniques are commonly employed which provide a single 2-dimensional view of the data. We describe ENS-t-SNE: an algorithm for Embedding Neighborhoods Simultaneously that…

Machine Learning · Computer Science 2024-04-02 Jacob Miller , Vahan Huroyan , Raymundo Navarrete , Md Iqbal Hossain , Stephen Kobourov

t-distributed Stochastic Neighborhood Embedding (t-SNE) is a method for dimensionality reduction and visualization that has become widely popular in recent years. Efficient implementations of t-SNE are available, but they scale poorly to…

Machine Learning · Computer Science 2019-02-26 George C. Linderman , Manas Rachh , Jeremy G. Hoskins , Stefan Steinerberger , Yuval Kluger

Hierarchical clustering is an important technique to organize big data for exploratory data analysis. However, existing one-size-fits-all hierarchical clustering methods often fail to meet the diverse needs of different users. To address…

Machine Learning · Computer Science 2020-09-22 Weikai Yang , Xiting Wang , Jie Lu , Wenwen Dou , Shixia Liu

Dimensionality reduction methods such as t-SNE and UMAP are popular methods for visualizing data with a potential (latent) clustered structure. They are known to group data points at the same time as they embed them, resulting in…

Machine Learning · Computer Science 2025-09-04 Elizabeth Coda , Ery Arias-Castro , Gal Mishne

Due to the sequential sample arrival, changing experiment conditions, and evolution of knowledge, the demand to continually visualize evolving structures of sequential and diverse single-cell RNA-sequencing (scRNA-seq) data becomes…

Genomics · Quantitative Biology 2024-06-24 Hui Ma , Kai Chen

The primary goal in cluster analysis is to discover natural groupings of objects. The field of cluster analysis is crowded with diverse methods that make special assumptions about data and address different scientific aims. Despite its…

Genomics · Quantitative Biology 2018-06-07 Gary K. Chen , Eric Chi , John Ranola , Kenneth Lange

Modern datasets and models are notoriously difficult to explore and analyze due to their inherent high dimensionality and massive numbers of samples. Existing visualization methods which employ dimensionality reduction to two or three…

Machine Learning · Computer Science 2018-08-01 David M. Chan , Roshan Rao , Forrest Huang , John F. Canny

Tree structures appear in many fields of the life sciences, including phylogenetics, developmental biology and nucleic acid structures. Trees can be used to represent RNA secondary structures, which directly relate to the function of…

Machine Learning · Computer Science 2026-01-22 Pengyu Liu , Mariel Vázquez , Nataša Jonoska

Motivation: Single cell RNA sequencing (scRNA-seq) data makes studying the development of cells possible at unparalleled resolution. Given that many cellular differentiation processes are hierarchical, their scRNA-seq data is expected to be…

Quantitative Methods · Quantitative Biology 2022-04-25 Quentin Garrido , Sebastian Damrich , Alexander Jäger , Dario Cerletti , Manfred Claassen , Laurent Najman , Fred Hamprecht

In this work we used unsupervised machine learning methods in order to find possible clustering structures in superconducting materials data sets. We used the SuperCon database, as well as our own data sets complied from literature, in…

Superconductivity · Physics 2022-07-13 B. Roter , N. Ninkovic , S. V. Dordevic

Semi-supervised clustering techniques have emerged as valuable tools for leveraging prior information in the form of constraints to improve the quality of clustering outcomes. Despite the proliferation of such methods, the ability to…

Machine Learning · Computer Science 2023-12-19 Guangjie Zeng , Hao Peng , Angsheng Li , Zhiwei Liu , Runze Yang , Chunyang Liu , Lifang He

We present GraphTSNE, a novel visualization technique for graph-structured data based on t-SNE. The growing interest in graph-structured data increases the importance of gaining human insight into such datasets by means of visualization.…

Machine Learning · Computer Science 2019-04-24 Yao Yang Leow , Thomas Laurent , Xavier Bresson

Spectral Clustering is a popular technique to split data points into groups, especially for complex datasets. The algorithms in the Spectral Clustering family typically consist of multiple separate stages (such as similarity matrix…

Machine Learning · Computer Science 2019-11-04 Yifei Wang , Rui Liu , Yong Chen , Hui Zhangs , Zhiwen Ye
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