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Predicting clinical outcome is remarkably important but challenging. Research efforts have been paid on seeking significant biomarkers associated with the therapy response or/and patient survival. However, these biomarkers are generally…

Machine Learning · Computer Science 2020-10-09 Jiancheng Yang , Jiajun Chen , Kaiming Kuang , Tiancheng Lin , Junjun He , Bingbing Ni

High-fidelity agent initialization is crucial for credible Agent-Based Modeling across diverse domains. A robust framework should be Topic-Adaptive, capturing macro-level joint distributions while ensuring micro-level individual…

Artificial Intelligence · Computer Science 2026-04-07 Rongxin Chen , Tianyu Wu , Bingbing Xu , Jiatang Luo , Xiucheng Xu , Huawei Shen

In order to automate AI research we introduce a full, end-to-end framework, OMEGA: Optimizing Machine learning by Evaluating Generated Algorithms, that starts at idea generation and ends with executable code. Our system combines structured…

Artificial Intelligence · Computer Science 2026-04-30 Jeremy Nixon , Annika Singh

Machine learning methods can detect complex relationships between variables, but usually do not exploit domain knowledge. This is a limitation because in many scientific disciplines, such as systems biology, domain knowledge is available in…

Artificial Intelligence · Computer Science 2023-07-31 Bastian Pfeifer , Hubert Baniecki , Anna Saranti , Przemyslaw Biecek , Andreas Holzinger

Despite the success of integrating large language models into the development of conversational systems, many studies have shown the effectiveness of retrieving and augmenting external knowledge for informative responses. Hence, many…

Computation and Language · Computer Science 2024-08-01 Xi Wang , Procheta Sen , Ruizhe Li , Emine Yilmaz

Automatic diagnosis has attracted increasing attention but remains challenging due to multi-step reasoning. Recent works usually address it by reinforcement learning methods. However, these methods show low efficiency and require…

Artificial Intelligence · Computer Science 2021-12-21 Junying Chen , Dongfang Li , Qingcai Chen , Wenxiu Zhou , Xin Liu

Machine learning provides a novel avenue for the study of experimental realizations of many-body systems, and has recently been proven successful in analyzing properties of experimental data of ultracold quantum gases. We here show that…

Computational Physics · Physics 2021-09-29 Corneel Casert , Kyle Mills , Tom Vieijra , Jan Ryckebusch , Isaac Tamblyn

Current Retrieval-Augmented Generation (RAG) systems primarily operate on unimodal textual data, limiting their effectiveness on unstructured multimodal documents. Such documents often combine text, images, tables, equations, and graphs,…

Machine Learning · Computer Science 2025-10-17 Rashmi R , Vidyadhar Upadhya

Retrieval augmented generation (RAG) has enhanced large language models by enabling access to external knowledge, with graph-based RAG emerging as a powerful paradigm for structured retrieval and reasoning. However, existing graph-based…

Artificial Intelligence · Computer Science 2026-02-06 Nengbo Wang , Tuo Liang , Vikash Singh , Chaoda Song , Van Yang , Yu Yin , Jing Ma , Jagdip Singh , Vipin Chaudhary

Scaling laws dictate that the performance of AI models is proportional to the amount of available data. Data augmentation is a promising solution to expanding the dataset size. Traditional approaches focused on augmentation using rotation,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Fazle Rahat , M Shifat Hossain , Md Rubel Ahmed , Sumit Kumar Jha , Rickard Ewetz

Agentic retrieval improves multi-hop question answering by giving language models autonomy to iteratively gather evidence. Recent work augments these systems with knowledge graphs for structured traversal, but this combination introduces…

Multiagent Systems · Computer Science 2026-05-19 Stockton Jenkins , Ramya Korlakai Vinayak , Junjie Hu

Expanding existing learning systems to provide high-quality customized models for more domains, such as new users, is challenged by the limited labeled data and the data and device heterogeneities. While knowledge distillation methods could…

Artificial Intelligence · Computer Science 2025-02-10 Gaole Dai , Huatao Xu , Yifan Yang , Rui Tan , Mo Li

Recently, Retrieval-Augmented Generation (RAG) has achieved remarkable success in addressing the challenges of Large Language Models (LLMs) without necessitating retraining. By referencing an external knowledge base, RAG refines LLM…

Artificial Intelligence · Computer Science 2024-09-11 Boci Peng , Yun Zhu , Yongchao Liu , Xiaohe Bo , Haizhou Shi , Chuntao Hong , Yan Zhang , Siliang Tang

In drug discovery, highly automated high-throughput laboratories are used to screen a large number of compounds in search of effective drugs. These experiments are expensive, so one might hope to reduce their cost by only experimenting on a…

Machine Learning · Computer Science 2025-04-15 Ihor Neporozhnii , Julien Roy , Emmanuel Bengio , Jason Hartford

For many complex diseases, prognosis is of essential importance. It has been shown that, beyond the main effects of genetic (G) and environmental (E) risk factors, the gene-environment (G$\times$E) interactions also play a critical role. In…

Applications · Statistics 2015-05-15 Hao Chai , Qingzhao Zhang , Yu Jiang , Guohua Wang , Sanguo Zhang , Shuangge Ma

The identification of predefined groups of genes ("gene-sets") which are differentially expressed between two conditions ("gene-set analysis", or GSA) is a very popular analysis in bioinformatics. GSA incorporates biological knowledge by…

Methodology · Statistics 2013-08-14 Nicolas Städler , Sach Mukherjee

Explainable recommendation systems provide explanations for recommendation results to improve their transparency and persuasiveness. The existing explainable recommendation methods generate textual explanations without explicitly…

Computation and Language · Computer Science 2021-10-26 Yidan Hu , Yong Liu , Chunyan Miao , Gongqi Lin , Yuan Miao

Retrieval-Augmented Generation (RAG) grounds large language models in external evidence, yet it still falters when answers must be pieced together across semantically distant documents. We close this gap with the Hierarchical Lexical Graph…

Exponential growth in scientific literature has heightened the demand for efficient evidence-based synthesis, driving the rise of the field of Automated Meta-analysis (AMA) powered by natural language processing and machine learning. This…

Artificial Intelligence · Computer Science 2025-04-30 Lingbo Li , Anuradha Mathrani , Teo Susnjak

Large language models (LLMs) augmented with retrieval systems have significantly advanced natural language processing tasks by integrating external knowledge sources, enabling more accurate and contextually rich responses. To improve the…

Computation and Language · Computer Science 2025-05-28 Xin Sun , Jianan Xie , Zhongqi Chen , Qiang Liu , Shu Wu , Yuehe Chen , Bowen Song , Weiqiang Wang , Zilei Wang , Liang Wang
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