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The problem of comparing trees representing the evolutionary histories of cancerous tumors has turned out to be crucial, since there is a variety of different methods which typically infer multiple possible trees. A departure from the…

Data Structures and Algorithms · Computer Science 2019-04-03 Giulia Bernardini , Paola Bonizzoni , Gianluca Della Vedova , Murray Patterson

We consider the numerical taxonomy problem of fitting a positive distance function ${D:{S\choose 2}\rightarrow \mathbb R_{>0}}$ by a tree metric. We want a tree $T$ with positive edge weights and including $S$ among the vertices so that…

Data Structures and Algorithms · Computer Science 2022-03-14 Vincent Cohen-Addad , Debarati Das , Evangelos Kipouridis , Nikos Parotsidis , Mikkel Thorup

Rotation distance between rooted binary trees measures the number of simple operations it takes to transform one tree into another. There are no known polynomial-time algorithms for computing rotation distance. We give an efficient,…

Data Structures and Algorithms · Computer Science 2018-03-19 Sean Cleary , Katherine St. John

Many popular algorithms for searching the space of leaf-labelled trees are based on tree rearrangement operations. Under any such operation, the problem is reduced to searching a graph where vertices are trees and (undirected) edges are…

Data Structures and Algorithms · Computer Science 2020-07-27 Lena Collienne , Alex Gavryushkin

Genome rearrangement has been an active area of research in computational comparative genomics for the last three decades. While initially mostly an interesting algorithmic endeavor, now the practical application by applying rearrangement…

Computational Complexity · Computer Science 2025-07-23 Luís Cunha , Thiago Lopes , Uéverton Souza , Leonard Bohnenkämper , Marília D. V. Braga , Jens Stoye

Kondo et al. (DS 2014) proposed methods for computing distances between unordered rooted trees by transforming an instance of the distance computing problem into an instance of the integer programming problem. They showed that the tree edit…

Data Structures and Algorithms · Computer Science 2017-06-13 Eunpyeong Hong , Yasuaki Kobayashi , Akihiro Yamamoto

Early literature on genome rearrangement modelling views the problem of computing evolutionary distances as an inherently combinatorial one. In particular, attention was given to estimating distances using the minimum number of events…

Populations and Evolution · Quantitative Biology 2023-01-12 Joshua Stevenson , Venta Terauds , Jeremy Sumner

In this article, we propose tree edit distance with variables, which is an extension of the tree edit distance to handle trees with variables and has a potential application to measuring the similarity between mathematical formulas,…

Data Structures and Algorithms · Computer Science 2021-05-12 Tatsuya Akutsu , Tomoya Mori , Naotoshi Nakamura , Satoshi Kozawa , Yuhei Ueno , Thomas N. Sato

Merge trees are fundamental structures in topological data analysis. Interleaving distance is a widely accepted metric for comparing merge trees, with applications in visualization and scientific computing. While a greedy algorithm exists…

Computational Geometry · Computer Science 2025-09-22 Elena Farahbakhsh Touli , Talha Bin Masood

The mutational heterogeneity of tumours can be described with a tree representing the evolutionary history of the tumour. With noisy sequencing data there may be uncertainty in the inferred tree structure, while we may also wish to study…

Computational Complexity · Computer Science 2025-01-14 Luís Cunha , Jack Kuipers , Thiago Lopes

The search for similarity and dissimilarity measures on phylogenetic trees has been motivated by the computation of consensus trees, the search by similarity in phylogenetic databases, and the assessment of clustering results in…

Populations and Evolution · Quantitative Biology 2011-11-09 Francesc Rossello , Gabriel Valiente

Genome rearrangements are events where large blocks of DNA exchange places during evolution. The analysis of these events is a promising tool for understanding evolutionary genomics, providing data for phylogenetic reconstruction based on…

Computational Complexity · Computer Science 2023-11-30 Luís Cunha , Ignasi Sau , Uéverton Souza

An ordered labeled tree is a tree in which the nodes are labeled and the left-to-right order among siblings is relevant. The edit distance between two ordered labeled trees is the minimum cost of changing one tree into the other through a…

Data Structures and Algorithms · Computer Science 2015-02-10 Shihyen Chen

A widely used method for determining the similarity of two labeled trees is to compute a maximum agreement subtree of the two trees. Previous work on this similarity measure is only concerned with the comparison of labeled trees of two…

Computer Vision and Pattern Recognition · Computer Science 2007-05-23 Ming-Yang Kao , Tak-Wah Lam , Wing-Kin Sung , Hing-Fung Ting

There are several tools available to infer phylogenetic trees, which depict the evolutionary relationships among biological entities such as viral and bacterial strains in infectious outbreaks, or cancerous cells in tumor progression trees.…

Data Structures and Algorithms · Computer Science 2023-12-22 António Pedro Branco , Cátia Vaz , Alexandre P. Francisco

A central theme in phylogenetics is the reconstruction and analysis of evolutionary trees from a given set of data. To determine the optimal search methods for reconstructing trees, it is crucial to understand the size and structure of the…

Populations and Evolution · Quantitative Biology 2016-08-15 Jamie V. de Jong , Jeanette C McLeod , Mike Steel

It is an open question whether there exists a polynomial-time algorithm for computing the rotation distances between pairs of extended ordered binary trees. The problem of computing the rotation distance between an arbitrary pair of trees,…

Data Structures and Algorithms · Computer Science 2020-01-20 Sean Cleary , Roland Maio

The matching distance is a computationally tractable topological measure to compare multi-filtered simplicial complexes. We design efficient algorithms for approximating the matching distance of two bi-filtered complexes to any desired…

Computational Geometry · Computer Science 2020-04-02 Michael Kerber , Arnur Nigmetov

The quartet distance is a measure of similarity used to compare two unrooted phylogenetic trees on the same set of $n$ leaves, defined as the number of subsets of four leaves related by a different topology in both trees. After a series of…

Data Structures and Algorithms · Computer Science 2020-12-03 Bartłomiej Dudek , Paweł Gawrychowski

The tree edit distance is a natural dissimilarity measure between rooted ordered trees whose nodes are labeled over an alphabet $\Sigma$. It is defined as the minimum number of node edits (insertions, deletions, and relabelings) required to…

Data Structures and Algorithms · Computer Science 2025-07-04 Tomasz Kociumaka , Ali Shahali
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