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Inverse problems are often ill-posed, with solutions that depend sensitively on data. In any numerical approach to the solution of such problems, regularization of some form is needed to counteract the resulting instability. This paper is…

Numerical Analysis · Mathematics 2009-09-14 S. L. Cotter , M. Dashti , A. M. Stuart

Repeat proteins are made with tandem copies of similar amino acid stretches that fold into elongated architectures. Due to their symmetry, these proteins constitute excellent model systems to investigate how evolution relates to structure,…

Biomolecules · Quantitative Biology 2022-10-12 Ezequiel A. Galpern , Jacopo Marchi , Thierry Mora , Aleksandra M. Walczak , Diego U. Ferreiro

Used as priors for Bayesian inverse problems, diffusion models have recently attracted considerable attention in the literature. Their flexibility and high variance enable them to generate multiple solutions for a given task, such as…

Machine Learning · Computer Science 2025-07-10 Emile Pierret , Bruno Galerne

Diffusion models have emerged as powerful tools for solving inverse problems, yet prior work has primarily focused on observations with Gaussian measurement noise, restricting their use in real-world scenarios. This limitation persists due…

Machine Learning · Statistics 2025-02-11 Alessandro Micheli , Mélodie Monod , Samir Bhatt

When considering fractional diffusion equation as model equation in analyzing anomalous diffusion processes, some important parameters in the model related to orders of the fractional derivatives, are often unknown and difficult to be…

Analysis of PDEs · Mathematics 2019-04-15 Zhiyuan Li , Yikan Liu , Masahiro Yamamoto

The Ising model is a model for pairwise interactions between binary variables that has become popular in the psychological sciences. It has been first introduced as a theoretical model for the alignment between positive (+1) and negative…

Methodology · Statistics 2020-03-16 Jonas Haslbeck , Sacha Epskamp , Maarten Marsman , Lourens Waldorp

It has become increasingly common to collect high-dimensional binary response data; for example, with the emergence of new sampling techniques in ecology. In smaller dimensions, multivariate probit (MVP) models are routinely used for…

Methodology · Statistics 2022-10-26 Antik Chakraborty , Rihui Ou , David B. Dunson

The inverse Gaussian (IG) is one of the most famous and considered distributions with positive support. We propose a convenient mode-based parameterization yielding the reparametrized IG (rIG) distribution; it allows/simplifies the use of…

Methodology · Statistics 2017-07-17 Antonio Punzo

Inverse problems are ubiquitous in the sciences and engineering. Two categories of inverse problems concerning a physical system are (1) estimate parameters in a model of the system from observed input-output pairs and (2) given a model of…

Methodology · Statistics 2023-12-05 Faaiq G. Waqar , Swati Patel , Cory M. Simon

Inverse Problem techniques offer powerful tools which deal naturally with marginal data and asymmetric or strongly smoothing kernels, in cases where parameter-fitting methods may be used only with some caution. Although they are typically…

Astrophysics · Physics 2007-05-23 Norman Gray , Iain J. Coleman

Maximum pseudolikelihood method has been among the most important methods for learning parameters of statistical physics models, such as Ising models. In this paper, we study how pseudolikelihood can be derived for learning parameters of a…

Machine Learning · Computer Science 2015-06-09 Onur Dikmen

An analysis is made of various methods of phenomenological renormalization based on finite-size scaling equations for inverse correlation lengths, the singular part of the free energy density, and their derivatives. The analysis is made…

Statistical Mechanics · Physics 2009-11-07 M. A. Yurishchev

Bayesian inverse problems use observed data to update a prior probability distribution for an unknown state or parameter of a scientific system to a posterior distribution conditioned on the data. In many applications, the unknown parameter…

Numerical Analysis · Mathematics 2026-05-12 Josie König , Elizabeth Qian , Melina A. Freitag

This article is devoted to inverse problems of recovering point sources in mathematical models of heat and mass transfer. The main attention is paid to well-posedness questions of these inverse problems with pointwise overdetermination…

Analysis of PDEs · Mathematics 2023-09-01 Sergey Pyatkov , Lyubov Neustroeva

Information field theory (IFT) is an emerging technique for posing infinite-dimensional inverse problems using the mathematics found in quantum field theory. Under IFT, the field inference task is formulated in a Bayesian setting where the…

Mathematical Physics · Physics 2025-05-27 Alex Alberts , Ilias Bilionis

The Wigner spiked model in a mismatched setting is studied with the finite temperature Statistical Mechanics approach through its representation as a Sherrington-Kirkpatrick model with added Mattis interaction. The exact solution of the…

Disordered Systems and Neural Networks · Physics 2022-04-20 Francesco Camilli , Pierluigi Contucci , Emanuele Mingione

Inverse protein folding is challenging due to its inherent one-to-many mapping characteristic, where numerous possible amino acid sequences can fold into a single, identical protein backbone. This task involves not only identifying viable…

Quantitative Methods · Quantitative Biology 2023-11-08 Kai Yi , Bingxin Zhou , Yiqing Shen , Pietro Liò , Yu Guang Wang

Inverse problems aim to determine parameters from observations, a crucial task in engineering and science. Lately, generative models, especially diffusion models, have gained popularity in this area for their ability to produce realistic…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Gabriel della Maggiora , Luis Alberto Croquevielle , Nikita Deshpande , Harry Horsley , Thomas Heinis , Artur Yakimovich

Two different approaches to dealing with probabilistic knowledge are examined -models and inductive inference. Examples of the first are: influence diagrams [1], Bayesian networks [2], log-linear models [3, 4]. Examples of the second are:…

Artificial Intelligence · Computer Science 2013-04-12 Norman C. Dalkey

Fitting probabilistic models to data is often difficult, due to the general intractability of the partition function and its derivatives. Here we propose a new parameter estimation technique that does not require computing an intractable…

Machine Learning · Computer Science 2015-03-13 Jascha Sohl-Dickstein , Peter Battaglino , Michael R. DeWeese
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