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Despite the advances in probabilistic model checking, the scalability of the verification methods remains limited. In particular, the state space often becomes extremely large when instantiating parameterized Markov decision processes…

Molecular Property Prediction (MPP) is a fundamental problem in drug discovery that has recently attracted growing attention. Large Language Models (LLMs), known for their impressive proficiency across domains, show promise as generalist…

Machine Learning · Computer Science 2026-05-28 Khiem Le , Sreejata Dey , Marcos Martínez Galindo , Vanessa Lopez , Ting Hua , Nitesh V. Chawla , Hoang Thanh Lam

Mixed-integer linear programs (MILPs) are extensively used to model practical problems such as planning and scheduling. A prominent method for solving MILPs is large neighborhood search (LNS), which iteratively seeks improved solutions…

Optimization and Control · Mathematics 2024-12-12 Wenbo Liu , Akang Wang , Wenguo Yang , Qingjiang Shi

In this paper, we consider the multiple probabilistic covering location problem (MPCLP), which attempts to open a fixed number of facilities to maximize the total covered customer demand under a joint probabilistic coverage setting. We…

Optimization and Control · Mathematics 2025-11-24 Yan-Ru Wang , Wei-Kun Chen , Ivana Ljubić

In many operational applications, it is necessary to routinely find, within a very limited time window, provably good solutions to challenging mixed-integer linear programming (MILP) problems. An example is the Security-Constrained Unit…

Optimization and Control · Mathematics 2022-08-23 Xiaoyi Gu , Santanu S. Dey , Álinson S. Xavier , Feng Qiu

We propose a new and strengthened Branch-and-Bound (BnB) algorithm for the maximum common (connected) induced subgraph problem based on two new operators, Long-Short Memory (LSM) and Leaf vertex Union Match (LUM). Given two graphs for which…

Data Structures and Algorithms · Computer Science 2022-01-19 Jianrong Zhou , Kun He , Jiongzhi Zheng , Chu-Min Li , Yanli Liu

This paper presents a method to certify the computational complexity of a standard Branch and Bound method for solving Mixed-Integer Quadratic Programming (MIQP) problems defined as instances of a multi-parametric MIQP. Beyond previous…

Systems and Control · Electrical Eng. & Systems 2022-04-06 Shamisa Shoja , Daniel Arnström , Daniel Axehill

The full strong branching (FSB) rule is well known to produce extremely small branch-and-bound trees. This rule guides branching decisions based exclusively on the information regarding local gains in the linear programming (LP) bounds. We…

Optimization and Control · Mathematics 2025-07-15 Prachi Shah , Santanu S. Dey

Branch and bound methods which are based on the principle "divide and conquer" are a well established solution approach in single-objective integer programming. In multi-objective optimization branch and bound algorithms are increasingly…

Optimization and Control · Mathematics 2024-01-08 Julius Bauß , Sophie N. Parragh , Michael Stiglmayr

Mixed-integer model predictive control (MI-MPC) requires the solution of a mixed-integer quadratic program (MIQP) at each sampling instant under strict timing constraints, where part of the state and control variables can only assume a…

Optimization and Control · Mathematics 2019-03-22 Pedro Hespanhol , Rien Quirynen , Stefano Di Cairano

Recent advancements have introduced machine learning frameworks to enhance the Branch and Bound (B\&B) branching policies for solving Mixed Integer Linear Programming (MILP). These methods, primarily relying on imitation learning of Strong…

Machine Learning · Computer Science 2024-02-07 Jiacheng Lin , Meng Xu , Zhihua Xiong , Huangang Wang

We study learning-augmented binary search trees (BSTs) via Treaps with carefully designed priorities. The result is a simple search tree in which the depth of each item $x$ is determined by its predicted weight $w_x$. Specifically, each…

Data Structures and Algorithms · Computer Science 2025-05-16 Jingbang Chen , Xinyuan Cao , Alicia Stepin , Li Chen

Retrieving relevant targets from an extremely large target set under computational limits is a common challenge for information retrieval and recommendation systems. Tree models, which formulate targets as leaves of a tree with trainable…

Machine Learning · Statistics 2020-06-30 Jingwei Zhuo , Ziru Xu , Wei Dai , Han Zhu , Han Li , Jian Xu , Kun Gai

Cutting planes (cuts) are crucial for solving Mixed Integer Linear Programming (MILP) problems. Advanced MILP solvers typically rely on manually designed heuristic algorithms for cut selection, which require much expert experience and…

Optimization and Control · Mathematics 2024-12-11 Xuefeng Zhang , Liangyu Chen , Zhengfeng Yang , Zhenbing Zeng

While chain-of-thought prompting with Best-of-N (BoN) selection has become popular for mathematical reasoning in large language models (LLMs), its linear structure fails to capture the branching and exploratory nature of complex…

Machine Learning · Computer Science 2025-10-24 Tristan Cinquin , Geoff Pleiss , Agustinus Kristiadi

Mixed integer linear programs are commonly solved by Branch and Bound algorithms. A key factor of the efficiency of the most successful commercial solvers is their fine-tuned heuristics. In this paper, we leverage patterns in real-world…

Machine Learning · Computer Science 2020-12-02 Marc Etheve , Zacharie Alès , Côme Bissuel , Olivier Juan , Safia Kedad-Sidhoum

This paper investigates the a-posteriori analysis of Branch-and-Bound~(BB) trees to extract structural information about the feasible region of mixed-binary linear programs. We introduce three novel outer approximations of the feasible…

Optimization and Control · Mathematics 2025-10-14 Marius Roland , Nagisa Sugishita , Alexandre Forel , Youssouf Emine , Ricardo Fukasawa , Thibaut Vidal

Branch-and-bound is a systematic enumerative method for combinatorial optimization, where the performance highly relies on the variable selection strategy. State-of-the-art handcrafted heuristic strategies suffer from relatively slow…

Machine Learning · Computer Science 2022-06-15 Tianyu Zhang , Amin Banitalebi-Dehkordi , Yong Zhang

Mixed-integer linear programming (MILP) has been a fundamental problem in combinatorial optimization. Conventional MILP solving mainly relies on carefully designed heuristics embedded in the branch-and-bound framework. Driven by the strong…

Artificial Intelligence · Computer Science 2026-01-13 Siyuan Li , Yifan Yu , Zhihao Zhang , Mengjing Chen , Fangzhou Zhu , Tao Zhong , Peng Liu , Jianye Hao

Tree-search decoding is an effective form of test-time scaling for large language models (LLMs), but real-world deployment imposes a fixed per-query token budget that varies across settings. Existing tree-search policies are largely…

Computation and Language · Computer Science 2026-02-11 Sora Miyamoto , Daisuke Oba , Naoaki Okazaki