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The Free-Energy Principle (FEP) [1-3] has been adopted in a variety of ambitious proposals that aim to characterize all adaptive, sentient, and cognitive systems within a unifying framework. Judging by the amount of attention it has…

Neurons and Cognition · Quantitative Biology 2024-01-18 Zahra Sheikhbahaee , Adam Safron , Casper Hesp , Guillaume Dumas

Existing adaptive bias techniques, which seek to estimate free energies and physical properties from molecular simulations, are limited by their reliance on fixed kernels or basis sets which hinder their ability to efficiently conform to…

Statistical Mechanics · Physics 2018-04-04 Hythem Sidky , Jonathan K. Whitmer

Based on a generative model (GM) and beliefs over hidden states, the free energy principle (FEP) enables an agent to sense and act by minimizing a free energy bound on Bayesian surprise. Inclusion of prior beliefs in the GM about desired…

Systems and Control · Electrical Eng. & Systems 2021-07-28 Thijs van de Laar , Ayça Özçelikkale , Henk Wymeersch

In this thesis we examine methodologies for determining free energy differences (FEDs) of phases via Monte Carlo simulation. We identify and address three generic issues that arise in FED calculations; the choice of representation, the…

Statistical Mechanics · Physics 2009-09-29 Arjun R. Acharya

The goal of these lecture notes is to review the problem of free energy minimization as a unified framework underlying the definition of maximum entropy modelling, generalized Bayesian inference, learning with latent variables, statistical…

Signal Processing · Electrical Eng. & Systems 2020-12-01 Sharu Theresa Jose , Osvaldo Simeone

Free energy perturbation (FEP) is considered the gold-standard simulation method for estimating small molecule binding affinity, a quantity of vital importance to drug discovery. The accuracy of FEP critically depends on an accurate model…

We study asymptotic properties of expectation propagation (EP) -- a method for approximate inference originally developed in the field of machine learning. Applied to generalized linear models, EP iteratively computes a multivariate…

Information Theory · Computer Science 2018-05-11 Burak Çakmak , Manfred Opper

Efficient feature selection from high-dimensional datasets is a very important challenge in many data-driven fields of science and engineering. We introduce a statistical mechanics inspired strategy that addresses the problem of sparse…

Machine Learning · Statistics 2021-04-07 Alfredo Braunstein , Thomas Gueudré , Andrea Pagnani , Mirko Pieropan

The perturbative expansion introduced by Zwanzig [R. W. Zwanzig, J. Chem. Phys. {\bf 22}, 1420 (1954)] expresses the difference in Helmholtz free energy between a system of interest and that of a reference system as series of cumulants…

Computational Physics · Physics 2020-10-01 C. W. Greeff

The free energy principle (FEP) from neuroscience provides a framework called active inference for the joint estimation and control of state space systems, subjected to colored noise. However, the active inference community has been…

Systems and Control · Electrical Eng. & Systems 2022-04-06 Ajith Anil Meera , Martijn Wisse

Modern deep neural networks achieved remarkable progress in medical image segmentation tasks. However, it has recently been observed that they tend to produce overconfident estimates, even in situations of high uncertainty, leading to…

Computer Vision and Pattern Recognition · Computer Science 2023-06-05 Agostina Larrazabal , Cesar Martinez , Jose Dolz , Enzo Ferrante

Mixture-of-Experts (MoE) models are typically pre-trained with explicit load-balancing constraints to ensure statistically balanced expert routing. Despite this, we observe that even well-trained MoE models exhibit significantly imbalanced…

Machine Learning · Computer Science 2026-01-27 Xuan-Phi Nguyen , Shrey Pandit , Austin Xu , Caiming Xiong , Shafiq Joty

Autonomous exploration is one of the important parts to achieve the fast autonomous mapping and target search. However, most of the existing methods are facing low-efficiency problems caused by low-quality trajectory or back-and-forth…

Robotics · Computer Science 2023-02-07 Yinghao Zhao , Li Yan , Hong Xie , Jicheng Dai , Pengcheng Wei

In the last decade, the free energy principle (FEP) and active inference (AIF) have achieved many successes connecting conceptual models of learning and cognition to mathematical models of perception and action. This effort is driven by a…

Artificial Intelligence · Computer Science 2024-11-25 Joséphine Pazem , Marius Krumm , Alexander Q. Vining , Lukas J. Fiderer , Hans J. Briegel

A scheme to provide various mean-field-type approximation algorithms is presented by employing the Bethe free energy formalism to a family of replicated systems in conjunction with analytical continuation with respect to the number of…

Disordered Systems and Neural Networks · Physics 2009-11-11 Yoshiyuki Kabashima

The brain is a biological system comprising nerve cells and orchestrates its embodied agent's perception, behavior, and learning in the dynamic environment. The free energy principle (FEP) advocated by Karl Friston explicates the local,…

Neurons and Cognition · Quantitative Biology 2024-10-07 Chang Sub Kim

We address the problem of planning under uncertainty, where an agent must choose actions that not only achieve desired outcomes but also reduce uncertainty. Traditional methods often treat exploration and exploitation as separate…

We present Free energy Estimators with Adaptive Transport (FEAT), a novel framework for free energy estimation -- a critical challenge across scientific domains. FEAT leverages learned transports implemented via stochastic interpolants and…

We propose an embodied system based on the free energy principle (FEP) for sensorimotor visual perception. We evaluated it in a character-recognition task using the MNIST dataset. Although the FEP has successfully described a rule that…

Neural and Evolutionary Computing · Computer Science 2022-02-23 Kanako Esaki , Tadayuki Matsumura , Kiyoto Ito , Hiroyuki Mizuno

Systems with many interacting stochastic constituents are fully characterized by their free energy. Computing this quantity is therefore the objective of various approaches, notably perturbative expansions, which are applied in problems…

Statistical Mechanics · Physics 2026-04-08 Tobias Kühn