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Optical coherence tomography angiography (OCTA) can non-invasively image the eye's circulatory system. In order to reliably characterize the retinal vasculature, there is a need to automatically extract quantitative metrics from these…
Visible light optical coherence tomography (vis-OCT) is gaining traction for retinal imaging due to its high resolution and functional capabilities. However, the significant absorption of hemoglobin in the visible light range leads to…
In this paper, we propose a framework that incorporates experts diagnostics and insights into the analysis of Optical Coherence Tomography (OCT) using multi-modal learning. To demonstrate the effectiveness of this approach, we create a…
Stroke is a major public health problem, affecting millions worldwide. Deep learning has recently demonstrated promise for enhancing the diagnosis and risk prediction of stroke. However, existing methods rely on costly medical imaging…
In this paper, we design a Generative Adversarial Network (GAN)-based solution for super-resolution and segmentation of optical coherence tomography (OCT) scans of the retinal layers. OCT has been identified as a non-invasive and…
Purpose. Localizing structures and estimating the motion of a specific target region are common problems for navigation during surgical interventions. Optical coherence tomography (OCT) is an imaging modality with a high spatial and…
The reliable segmentation of retinal vasculature can provide the means to diagnose and monitor the progression of a variety of diseases affecting the blood vessel network, including diabetes and hypertension. We leverage the power of…
Automatically identifying the structural substrates underlying cardiac abnormalities can potentially provide real-time guidance for interventional procedures. With the knowledge of cardiac tissue substrates, the treatment of complex…
Optical coherence tomography angiography (OCTA) is an imaging technique that allows for non-invasive investigation of the microvasculature in the retina. OCTA uses laser light reflectance to measure moving blood cells. Hereby, it visualizes…
Optical coherence tomography (OCT) scanning is useful in detecting various retinal diseases. However, there are not enough ophthalmologists who can diagnose retinal OCT images in much of the world. To provide OCT screening inexpensively and…
In the last decade, various robotic platforms have been introduced that could support delicate retinal surgeries. Concurrently, to provide semantic understanding of the surgical area, recent advances have enabled microscope-integrated…
Accurate segmentation of macular edema, a hallmark pathological feature in vision-threatening conditions such as age-related macular degeneration and diabetic macular edema, is essential for clinical diagnosis and management. To overcome…
An accurate and automated tissue segmentation algorithm for retinal optical coherence tomography (OCT) images is crucial for the diagnosis of glaucoma. However, due to the presence of the optic disc, the anatomical structure of the…
The vascular structure of blood vessels is important in diagnosing retinal conditions such as glaucoma and diabetic retinopathy. Accurate segmentation of these vessels can help in detecting retinal objects such as the optic disc and optic…
Optical coherence tomography (OCT) is a non-invasive imaging technique widely used for ophthalmology. It can be extended to OCT angiography (OCT-A), which reveals the retinal vasculature with improved contrast. Recent deep learning…
Retinal optical coherence tomography (OCT) and OCT angiography (OCTA) suffer from the degeneration of image quality due to speckle noise and bulk-motion noise, respectively. Because the cross-sectional retina has distinct features in OCT…
Segmentation of retinal vessel images is critical to the diagnosis of retinopathy. Recently, convolutional neural networks have shown significant ability to extract the blood vessel structure. However, it remains challenging to refined…
This paper presents a novel automated system that segments six sub-retinal layers from optical coherence tomography (OCT) image stacks of healthy patients and patients with diabetic macular edema (DME). First, each image in the OCT stack is…
Accurate and repeatable delineation of corneal tissue interfaces is necessary for surgical planning during anterior segment interventions, such as Keratoplasty. Designing an approach to identify interfaces, which generalizes to datasets…
Optical diffraction tomography (ODT) is a powerful technique for quantitative, label-free reconstruction of the three-dimensional refractive index (RI) distribution of biological samples. While ODT is well established for imaging thin,…