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Spontaneous neural activity, crucial in memory, learning, and spatial navigation, often manifests itself as repetitive spatiotemporal patterns. Despite their importance, analyzing these patterns in large neural recordings remains…

Signal Processing · Electrical Eng. & Systems 2024-05-15 Roman Koshkin , Tomoki Fukai

The ability to accurately model the fitness landscape of protein sequences is critical to a wide range of applications, from quantifying the effects of human variants on disease likelihood, to predicting immune-escape mutations in viruses…

Machine Learning · Computer Science 2022-05-30 Pascal Notin , Mafalda Dias , Jonathan Frazer , Javier Marchena-Hurtado , Aidan Gomez , Debora S. Marks , Yarin Gal

Our work tackles the fundamental challenge of image segmentation in computer vision, which is crucial for diverse applications. While supervised methods demonstrate proficiency, their reliance on extensive pixel-level annotations limits…

Computer Vision and Pattern Recognition · Computer Science 2024-11-11 Boujemaa Guermazi , Naimul Khan

Genomic signal processing has been used successfully in bioinformatics to analyze biomolecular sequences and gain varied insights into DNA structure, gene organization, protein binding, sequence evolution, etc. But challenges remain in…

Genomics · Quantitative Biology 2022-11-04 Saish Jaiswal , Shreya Nema , Hema A Murthy , Manikandan Narayanan

This paper demonstrates the utility of organized numerical representations of genes in research involving flat string gene formats (i.e., FASTA/FASTQ5). FASTA/FASTQ files have several current limitations, such as their large file sizes,…

Genomics · Quantitative Biology 2023-08-11 Daniel H. Um , David A. Knowles , Gail E. Kaiser

The ability to generate natural language sequences from source code snippets has a variety of applications such as code summarization, documentation, and retrieval. Sequence-to-sequence (seq2seq) models, adopted from neural machine…

Machine Learning · Computer Science 2019-02-22 Uri Alon , Shaked Brody , Omer Levy , Eran Yahav

While transformer-based Large Language Models (LLMs) theoretically support massive context windows, they suffer from severe performance degradation when processing long numerical sequences. We attribute this failure to the attention…

Computation and Language · Computer Science 2026-04-10 Jie Sun , Yu Liu , Lu Han , Qiwen Deng , Xiang Shu , Yang Xiao , Xingyu Lu , Jun Zhou , Pengfei Liu , Lintao Ma , Jiancan Wu , Xiang Wang

Achieving faster execution with shorter compilation time can foster further diversity and innovation in neural networks. However, the current paradigm of executing neural networks either relies on hand-optimized libraries, traditional…

Machine Learning · Computer Science 2020-01-27 Byung Hoon Ahn , Prannoy Pilligundla , Amir Yazdanbakhsh , Hadi Esmaeilzadeh

Semi-supervised semantic segmentation in computational pathology remains challenging due to scarce pixel-level annotations and unreliable pseudo-label supervision. We propose UniSemAlign, a dual-modal semantic alignment framework that…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Le-Van Thai , Tien Dat Nguyen , Hoai Nhan Pham , Lan Anh Dinh Thi , Duy-Dong Nguyen , Ngoc Lam Quang Bui

Recently, records on stereo matching benchmarks are constantly broken by end-to-end disparity networks. However, the domain adaptation ability of these deep models is quite poor. Addressing such problem, we present a novel domain-adaptive…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Xiao Song , Guorun Yang , Xinge Zhu , Hui Zhou , Zhe Wang , Jianping Shi

Existing works on coreference resolution suggest that task-specific models are necessary to achieve state-of-the-art performance. In this work, we present compelling evidence that such models are not necessary. We finetune a pretrained…

Computation and Language · Computer Science 2023-10-24 Wenzheng Zhang , Sam Wiseman , Karl Stratos

Liver tumor segmentation is essential for computer-aided diagnosis, surgical planning, and prognosis evaluation. However, obtaining and maintaining a large-scale dataset with dense annotations is challenging. Semi-Supervised Learning (SSL)…

Computer Vision and Pattern Recognition · Computer Science 2024-05-21 Shiyun Chen , Li Lin , Pujin Cheng , Xiaoying Tang

The security of open-source software repositories is increasingly threatened by next-gen software supply chain attacks. These attacks include multiphase malware execution, remote access activation, and dynamic payload generation.…

Cryptography and Security · Computer Science 2026-04-30 Sk Tanzir Mehedi , Raja Jurdak , Chadni Islam , Abu Bakar Siddique Mahi , Gowri Ramachandran

We theorize that phylogenetic profiles provide a quantitative method that can relate the structural and functional properties of proteins, as well as their evolutionary relationships. A key feature of phylogenetic profiles is the…

Quantitative Methods · Quantitative Biology 2009-11-04 Yoojin Hong , Jaewoo Kang , Dongwon Lee , Randen L. Patterson , Damian B. van Rossum

Predicting gene function from its DNA sequence is a fundamental challenge in biology. Many deep learning models have been proposed to embed DNA sequences and predict their enzymatic function, leveraging information in public databases…

Prompting, which casts downstream applications as language modeling tasks, has shown to be sample efficient compared to standard fine-tuning with pre-trained models. However, one pitfall of prompting is the need of manually-designed…

Computation and Language · Computer Science 2022-09-21 Zichun Yu , Tianyu Gao , Zhengyan Zhang , Yankai Lin , Zhiyuan Liu , Maosong Sun , Jie Zhou

We present Theseus, an efficient application-agnostic open source library for differentiable nonlinear least squares (DNLS) optimization built on PyTorch, providing a common framework for end-to-end structured learning in robotics and…

Event Sequences (EvS) refer to sequential data characterized by irregular sampling intervals and a mix of categorical and numerical features. Accurate classification of these sequences is crucial for various real-life applications,…

Machine Learning · Computer Science 2025-02-27 Dmitry Osin , Igor Udovichenko , Viktor Moskvoretskii , Egor Shvetsov , Evgeny Burnaev

Modern SoC datapaths include deeply pipelined, domain-specific accelerators, but their RTL implementation and verification are still mostly done by hand. While large language models (LLMs) exhibit advanced code-generation abilities for…

Hardware Architecture · Computer Science 2025-08-11 Suresh Purini , Siddhant Garg , Mudit Gaur , Sankalp Bhat , Sohan Mupparapu , Arun Ravindran

Multi-hop all-reduce is the de facto backbone of large model training. As the training scale increases, the network often becomes a bottleneck, motivating reducing the volume of transmitted data. Accordingly, recent systems demonstrated…

Machine Learning · Computer Science 2026-02-10 Wenchen Han , Shay Vargaftik , Michael Mitzenmacher , Ran Ben Basat