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Network flows often exhibit a hierarchical tree-like structure that can be attributed to the minimisation of dissipation. The common feature of such systems is a single source and multiple sinks (or vice versa). In contrast, here we study…

Tissues and Organs · Quantitative Biology 2020-05-27 Julius B. Kirkegaard , Kim Sneppen

Understanding the dynamic nature of biological systems is fundamental to deciphering cellular behavior, developmental processes, and disease progression. Single-cell RNA sequencing (scRNA-seq) has provided static snapshots of gene…

Quantitative Methods · Quantitative Biology 2025-05-02 Zhenyi Zhang , Yuhao Sun , Qiangwei Peng , Tiejun Li , Peijie Zhou

The growth of urban areas intensifies the need for sustainable, efficient transportation infrastructure and mobility systems, driving initiatives to enhance infrastructure and public transit while reducing traffic congestion and emissions.…

Physics and Society · Physics 2026-04-17 Oluwaleke Yusuf , Adil Rasheed , Frank Lindseth

We study the urban-scale macroscopic traffic flow in city networks. Star graph is considered as traffic network. Star graphs with controlled traffic flow are transformed to various cell-transmission graphs by using the cell transmission…

Adaptation and Self-Organizing Systems · Physics 2019-12-10 Takashi Nagatani

The regulation of metabolic activity by tuning enzyme expression levels is crucial to sustain cellular growth in changing environments. Metabolic networks are often studied at steady state using constraint-based models and optimization…

Molecular Networks · Quantitative Biology 2014-10-24 Steffen Waldherr , Diego A. Oyarzún , Alexander Bockmayr

Network science has become an essential interdisciplinary tool for understanding complex biological systems. However, because these systems undergo continuous, often stimulus-driven changes in both structure and function, traditional static…

Molecular Networks · Quantitative Biology 2025-05-19 Abir Khazaal , Fatemeh Vafaee

RNA velocity is an important model that combines cellular spliced and unspliced RNA counts to infer dynamical properties of various regulatory functions. Despite its wide applicability and many variants used in practice, the model has not…

Dynamical Systems · Mathematics 2026-01-06 Boya Hou , Maxim Raginsky , Abhishek Pandey , Olgica Milenkovic

In this paper, we introduce DynaRoute, an adaptive joint optimization framework for dynamic vehicular networks that simultaneously addresses platoon control and data transmission through trajectory-aware routing and safety-constrained…

Systems and Control · Electrical Eng. & Systems 2025-06-11 Chen Huang , Dingxuan Wang , Ronghui Hou

Network inference, the task of reconstructing interactions in a complex system from experimental observables, is a central yet extremely challenging problem in systems biology. While much progress has been made in the last two decades,…

Quantitative Methods · Quantitative Biology 2024-09-12 Stephen Y Zhang

Accurately modeling complex dynamic spatio-temporal systems requires capturing flow-mediated interdependencies and context-sensitive interaction dynamics. Existing methods, predominantly graph-based or attention-driven, rely on…

Machine Learning · Computer Science 2025-11-11 Yutong Feng , Xu Liu , Yutong Xia , Yuxuan Liang

The topic of this study lies in the intersection of two fields. One is related with analyzing transport phenomena in complicated flows.For this purpose, we use so-called coherent sets: non-dispersing, possibly moving regions in the flow's…

Numerical Analysis · Mathematics 2021-07-28 Péter Koltai , Johannes von Lindheim , Sebastian Neumayer , Gabriele Steidl

Understanding cellular trajectories via time-resolved single-cell transcriptomics is vital for studying development, regeneration, and disease. A key challenge is inferring continuous trajectories from discrete snapshots. Biological…

Most recent advances in machine learning and analytics for process control pose the question of how to naturally integrate new data-driven methods with classical process models and control. We propose a process modeling framework enabling…

Neural and Evolutionary Computing · Computer Science 2025-08-08 Michael R. Wartmann , B. Erik Ydstie

Recent advances in sensor and mobile devices have enabled an unprecedented increase in the availability and collection of urban trajectory data, thus increasing the demand for more efficient ways to manage and analyze the data being…

Databases · Computer Science 2020-12-15 Sheng Wang , Zhifeng Bao , J. Shane Culpepper , Gao Cong

Temporal networks model how the interaction between elements in a complex system evolve over time. Just like complex systems display collective dynamics, here we interpret temporal networks as trajectories performing a collective motion in…

Social and Information Networks · Computer Science 2022-10-18 Lucas Lacasa , Jorge P. Rodriguez , Victor M. Eguiluz

Diffusion and flow-matching have emerged as powerful methodologies for generative modeling, with remarkable success in capturing complex data distributions and enabling flexible guidance at inference time. Many downstream applications,…

Machine Learning · Computer Science 2026-04-28 Zeyang Li , Kaveh Alim , Navid Azizan

Traffic learning and prediction is at the heart of the evaluation of the performance of telecommunications networks and attracts a lot of attention in wired broadband networks. Now, benefiting from the big data in cellular networks, it…

Networking and Internet Architecture · Computer Science 2017-03-29 Rongpeng Li , Zhifeng Zhao , Jianchao Zheng , Chengli Mei , Yueming Cai , Honggang Zhang

Optimal transport (OT) and Schr{\"o}dinger bridge (SB) problems have emerged as powerful frameworks for transferring probability distributions with minimal cost. However, existing approaches typically focus on endpoint matching while…

Optimization and Control · Mathematics 2025-10-09 Xu Duan , Dongmei Chen

We propose to predict the future trajectories of observed agents (e.g., pedestrians or vehicles) by estimating and using their goals at multiple time scales. We argue that the goal of a moving agent may change over time, and modeling goals…

Computer Vision and Pattern Recognition · Computer Science 2022-03-29 Chuhua Wang , Yuchen Wang , Mingze Xu , David J. Crandall

Among the most prevalent motion planning techniques, sampling and trajectory optimization have emerged successful due to their ability to handle tight constraints and high-dimensional systems, respectively. However, limitations in sampling…

Robotics · Computer Science 2021-07-30 Kalyan Vasudev Alwala , Mustafa Mukadam