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Self-assembly of complex and functional materials remains a grand challenge in soft material science. Efficient assembly depends on a delicate balance between thermodynamic and kinetic effects, requiring fine-tuning affinities and…

Soft Condensed Matter · Physics 2024-11-14 Wei-Shao Wei , Anthony Trubiano , Christian Sigl , Stefan Paquay , Hendrik Dietz , Michael F. Hagan , Seth Fraden

Cellular self-assembly and organization are fundamental steps for the development of biological tissues. In this paper, within the framework of a cellular automata model, we address how an ordered tissue pattern spontaneously emerges from a…

Biological Physics · Physics 2019-10-24 Debangana Mukhopadhyay , Rumi De

In this paper, we study the minimum number of unique tile types required for the self-assembly of thin rectangles in Winfree's abstract Tile Assembly Model (aTAM), restricted to temperature-1. Using Catalan numbers, planar self-assembly and…

Computational Geometry · Computer Science 2019-06-18 David Furcy , Scott M. Summers , Christian Wendlandt

A major goal in nanoscience and nanotechnology is the self-assembly of any desired complex structure with a system of particles interacting through simple potentials. To achieve this objective, intense experimental and theoretical efforts…

Soft Condensed Matter · Physics 2014-09-11 Daniel Salgado-Blanco , Carlos I. Mendoza

Self-closing assembly is prone to polymorphism due to thermally-excited bending fluctuations, which permit the formation of off-target assemblies at the point of self-closure. One way to overcome this source of polymorphism is to use…

Soft Condensed Matter · Physics 2025-11-06 Sirui Liu , Thomas E. Videbæk , W. Benjamin Rogers

Motivated by targeted drug delivery, we investigate the gathering of particles in the full tilt model of externally controlled motion planning: A set of particles is located at the tiles of a polyomino with all particles reacting uniformly…

Computational Geometry · Computer Science 2026-03-04 Sándor P. Fekete , Jonas Friemel , Peter Kramer , Jan-Marc Reinhardt , Christian Rieck , Christian Scheffer

A series of simulations aimed at elucidating the self-assembly dynamics of spherical virus capsids is described. This little-understood phenomenon is a fascinating example of the complex processes that occur in the simplest of organisms.…

Soft Condensed Matter · Physics 2015-05-19 D. C. Rapaport

Active matter physics and swarm robotics have provided powerful tools for the study and control of ensembles driven by internal sources. At the macroscale, controlling swarms typically utilizes significant memory, processing power, and…

Assembly of multi-part physical structures is both a valuable end product for autonomous robotics, as well as a valuable diagnostic task for open-ended training of embodied intelligent agents. We introduce a naturalistic physics-based…

Strand displacement and tile assembly systems are designed to follow prescribed kinetic rules (i.e., exhibit a specific time-evolution). However, the expected behavior in the limit of infinite time--known as thermodynamic equilibrium--is…

Emerging Technologies · Computer Science 2017-09-26 David Doty , Trent A. Rogers , David Soloveichik , Chris Thachuk , Damien Woods

Biomolecular condensates self-assemble when proteins and nucleic acids spontaneously demix to form droplets within the crowded intracellular milieu. This simple mechanism underlies the formation of a wide variety of membraneless…

Statistical Mechanics · Physics 2021-06-30 William M. Jacobs

Cellular functions are established through biological evolution, but are constrained by the laws of physics. For instance, the physics of protein folding limits the lengths of cellular polypeptide chains. Consequently, many cellular…

Biological Physics · Physics 2019-07-09 Pablo Sartori , Stanislas Leibler

Equilibrium self-assembly and conventional materials processing techniques fall far short of mimicking dynamic self-actuating processes that are commonplace throughout biology. To bridge the gap between living and synthetic matter, we study…

Thanks to a constant energy input, active matter can self-assemble into phases with complex architectures and functionalities such as living clusters that dynamically form, reshape and break-up, which are forbidden in equilibrium materials…

Soft Condensed Matter · Physics 2019-03-27 Falko Schmidt , Benno Liebchen , Hartmut Löwen , Giovanni Volpe

We develop a class of models with which we simulate the assembly of particles into T1 capsid-like objects using Newtonian dynamics. By simulating assembly for many different values of system parameters, we vary the forces that drive…

Biomolecules · Quantitative Biology 2009-11-11 Michael F. Hagan , David Chandler

We report numerical simulations of membrane tubulation driven by large colloidal particles. Using Monte Carlo simulations we study how the process depends on particle size, concentration and binding strength, and present accurate free…

Soft Condensed Matter · Physics 2015-06-05 Andela Šarić , Angelo Cacciuto

We present a series of results related to mathematical models of self-assembling tiles and the impacts that three diverse properties have on their dynamics. We expand upon a series of prior results which showed that (1) the abstract Tile…

Computational Geometry · Computer Science 2019-10-10 Daniel Hader , Aaron Koch , Matthew J. Patitz , Michael Sharp

Harnessing the intrinsic dynamics of physical systems for information processing opens new avenues for computation embodied in matter. Using simulations of a model system, we show that assemblies of DNA tiles capable of self-organizing into…

Soft Condensed Matter · Physics 2025-10-23 Tim E. Veenstra , René van Roij , Marjolein Dijkstra

Solute trapping is an important phenomenon in rapid solidification of alloys, for which the continuous growth model (CGM) is a popular sharp interface theory. Using matched asymptotic analysis, we show how to quantitatively map the sharp…

Materials Science · Physics 2018-09-17 Tatu Pinomaa , Nikolas Provatas

In geometrically frustrated assemblies, equilibrium self-limitation manifests in the form of a minimum in the free energy per subunit at a finite, multi-subunit size which results from the competition between the elastic costs of…

Soft Condensed Matter · Physics 2023-08-15 Michael Wang , Gregory Grason