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Many types of mammalian cells exert active contractile forces and mechanically deform their elastic substrate, to accomplish biological functions such as cell migration. These substrate deformations provide a mechanism by which cells can…

Soft Condensed Matter · Physics 2022-02-22 Subhaya Bose , Patrick S. Noerr , Ajay Gopinathan , Arvind Gopinath , Kinjal Dasbiswas

The origin of rigidity in disordered materials is an outstanding open problem in statistical physics. Previously, a class of 2D cellular models has been shown to undergo a rigidity transition controlled by a mechanical parameter that…

Soft Condensed Matter · Physics 2023-01-18 Matthias Merkel , Lisa Manning

During embryonic development, structures with complex geometry can emerge from planar epithelial monolayers and to study these shape transitions is of key importance for revealing the biophysical laws involved in the morphogenesis of…

Soft Condensed Matter · Physics 2023-08-29 Daria S. Roshal , Karim Azzag , Kirill K. Fedorenko , Sergei B. Rochal , Stephen Baghdiguian

Microgels are soft colloidal particles constituted by cross-linked polymer networks with a high potential for applications. In particular, after adsorption at a fluid interface, interfacial tension provides two-dimensional (2D) confinement…

Soft Condensed Matter · Physics 2021-09-03 Jacopo Vialetto , Natalie Nussbaum , Jotam Bergfreund , Peter Fischer , Lucio Isa

The processing of thin-structured materials in a fluidic environment, from nearly inextensible but flexible graphene sheets to highly extensible polymer films, arises in many applications. So far, little is known about the dynamics of such…

Soft Condensed Matter · Physics 2022-02-15 Yijiang Yu , Michael D. Graham

The organization of live cells to tissues is associated with the mechanical interaction between cells, which is mediated through their elastic environment. We model cells as spherical active force dipoles surrounded by an infinite elastic…

Biological Physics · Physics 2017-06-08 Roman Golkov , Yair Shokef

After a brief introduction to several variational problems in the study of shapes of thin thickness structures, we deal with variational problems on 2-dimensional surface in 3-dimensional Euclidian space by using exterior differential…

Mathematical Physics · Physics 2007-05-23 Z. C. Tu , Z. C. Ou-Yang

Models for fluid deformable surfaces provide valid theories to describe the dynamics of thin fluidic sheets of soft materials. To use such models in morphogenesis and development requires to incorporate active forces. We consider active…

Mathematical Physics · Physics 2024-08-20 Maik Porrmann , Axel Voigt

In order to describe two-dimensionally packed cells in epithelial tissues both mathematically and physically, there have been developed several sorts of geometrical models, such as the vertex model, the finite element model, the…

Biological Physics · Physics 2014-11-19 Yukitaka Ishimoto , Yoshihiro Morishita

The response of amorphous solids to a mechanical perturbation consists in an elastic and a plastic deformation. The latter is mediated by localized irreversible rearrangements associated with Eshelby-like quadrupolar singularities in the…

Soft Condensed Matter · Physics 2026-04-13 Gilles Tarjus , Misaki Ozawa , Giulio Biroli

The multiplicative decomposition model is widely employed for predicting residual stresses and morphologies of biological tissues due to growth. However, it relies on the assumption that the tissue is initially in a stress-free state, which…

Soft Condensed Matter · Physics 2020-09-04 Yangkun Du , Chaofeng Lü , Weiqiu Chen , Michel Destrade

Motivated by recent studies of two-phase lipid vesicles possessing 2D solid domains integrated within a fluid bilayer phase, we study the shape equilibria of closed vesicles possessing a single planar, circular inclusion. While 2D solid…

Soft Condensed Matter · Physics 2024-04-16 Geunwoong Jeon , Justin Fagnoni , Hao Wan , Maria M. Santore , Gregory M. Grason

Recent experimental observations have suggested that topological defects can facilitate the creation of sharp features in developing embryos. Whereas these observations echo established knowledge about the interplay between geometry and…

Soft Condensed Matter · Physics 2023-07-25 Ludwig A. Hoffmann , Livio Nicola Carenza , Luca Giomi

During the spreading of epithelial tissues, the advancing tissue front often develops fingerlike protrusions. Their resemblance to traditional viscous fingering patterns in driven fluids suggests that epithelial fingers could arise from an…

Biological Physics · Physics 2019-03-05 Ricard Alert , Carles Blanch-Mercader , Jaume Casademunt

In this article, we propose a general framework to study the dynamics and topology of cellular networks that capture the geometry of cell packings in two-dimensional tissues. Such epithelia undergo large-scale deformation during…

Tissues and Organs · Quantitative Biology 2017-09-08 Matthias Merkel , Raphaël Etournay , Marko Popović , Guillaume Salbreux , Suzanne Eaton , Frank Jülicher

Natural slender structures, such as plant leaves, petals, and tendrils, often exhibit complex three-dimensional (3D) morphologies-including twisting, helical coiling, and saddle-bending-driven by differential growth. The resulting internal…

Soft Condensed Matter · Physics 2025-06-24 Hao Liu , Mingwu Li , Dabiao Liu

The buckling of a soft elastic sample under growth or swelling has highlighted a new interest in materials science, morphogenesis, and biology or physiology. Indeed, the change of mass or volume is a common fact of any living species, and…

Soft Condensed Matter · Physics 2023-09-21 Martine Ben Amar

The vertex model is a popular framework for modelling tightly packed biological cells, such as confluent epithelia. Cells are described by convex polygons tiling the plane and their equilibrium is found by minimizing a global mechanical…

Biological Physics · Physics 2021-03-17 Oliver E. Jensen , Emma Johns , Sarah Woolner

We simulate a two dimensional model of self-propelled particles confined by a deformable boundary. The particles tend to accumulate near the boundary and the shape of the boundary deforms upon the collisions. We find that there are two…

Soft Condensed Matter · Physics 2018-05-18 Wen-de Tian , Yong-kun Guo , Kang Chen , Yu-qiang Ma

Surface growth is a crucial component of many natural and artificial processes from cell proliferation to additive manufacturing. In elastic systems surface growth is usually accompanied by the development of geometrical incompatibility…

Soft Condensed Matter · Physics 2019-05-08 Lev Truskinovsky , Giuseppe Zurlo