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Motivation: Structural heterogeneity in single-particle cryo-electron microscopy (cryo-EM) data represents a major challenge for high-resolution structure determination. Unsupervised classification may serve as the first step in the…

Data Analysis, Statistics and Probability · Physics 2017-11-01 Jiayi Wu , Yong-Bei Ma , Charles Congdon , Bevin Brett , Shuobing Chen , Qi Ouyang , Youdong Mao

We present a novel unsupervised learning approach to automatically segment and label images in astronomical surveys. Automation of this procedure will be essential as next-generation surveys enter the petabyte scale: data volumes will…

Instrumentation and Methods for Astrophysics · Physics 2015-07-08 Alex Hocking , James E. Geach , Neil Davey , Yi Sun

Deep neural networks (DNNs) offer a means of addressing the challenging task of clustering high-dimensional data. DNNs can extract useful features, and so produce a lower dimensional representation, which is more amenable to clustering…

Machine Learning · Computer Science 2021-07-23 Louis Mahon , Thomas Lukasiewicz

Clustering methods are a valuable tool for the identification of patterns in high dimensional data with applications in many scientific problems. However, quantifying uncertainty in clustering is a challenging problem, particularly when…

Methodology · Statistics 2018-06-01 Marcio Valk , Gabriela Bettella Cybis

In this paper, we address an issue of finding explainable clusters of class-uniform data in labelled datasets. The issue falls into the domain of interpretable supervised clustering. Unlike traditional clustering, supervised clustering aims…

Machine Learning · Computer Science 2023-07-18 Natallia Kokash , Leonid Makhnist

We propose to bridge the gap between semi-supervised and unsupervised image recognition with a flexible method that performs well for both generalized category discovery (GCD) and image clustering. Despite the overlap in motivation between…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Gihan Jayatilaka , Abhinav Shrivastava , Matthew Gwilliam

Cancer radiomics is an emerging discipline promising to elucidate lesion phenotypes and tumor heterogeneity through patterns of enhancement, texture, morphology, and shape. The prevailing technique for image texture analysis relies on the…

Applications · Statistics 2020-11-12 Xiao Li , Michele Guindani , Chaan S. Ng , Brian P. Hobbs

Traditional studies of stellar clusters in external galaxies use surface photometry and therefore focus on systems that are still bright and compact enough to be separated from the stellar background. Consequently, the latter stages of…

Astrophysics · Physics 2007-05-23 Anne Pellerin , Martin Meyer , Jason Harris , Daniela Calzetti

Risk stratification is a key tool in clinical decision-making, yet current approaches often fail to translate sophisticated survival analysis into actionable clinical criteria. We present a novel method for unsupervised machine learning…

Sharing images online poses security threats to a wide range of users due to the unawareness of privacy information. Deep features have been demonstrated to be a powerful representation for images. However, deep features usually suffer from…

Computer Vision and Pattern Recognition · Computer Science 2020-01-23 Chiranjibi Sitaula , Yong Xiang , Sunil Aryal , Xuequan Lu

Modern deep neural networks have shown remarkable performance in medical image classification. However, such networks either emphasize pixel-intensity features instead of fundamental anatomical structures (e.g., those encoded by topological…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Pengfei Gu , Huimin Li , Haoteng Tang , Dongkuan , Xu , Erik Enriquez , DongChul Kim , Bin Fu , Danny Z. Chen

We propose a novel methodology for feature screening in clustering massive datasets, in which both the number of features and the number of observations can potentially be very large. Taking advantage of a fusion penalization based convex…

Methodology · Statistics 2017-10-05 Trambak Banerjee , Gourab Mukherjee , Peter Radchenko

We develop a supervised-learning-based approach for monitoring and diagnosing texture-related defects in manufactured products characterized by stochastic textured surfaces that satisfy the locality and stationarity properties of Markov…

Applications · Statistics 2017-07-24 Anh Tuan Bui , Daniel W. Apley

Traditional clustering methods often perform clustering with low-level indiscriminative representations and ignore relationships between patterns, resulting in slight achievements in the era of deep learning. To handle this problem, we…

Machine Learning · Computer Science 2019-05-07 Jianlong Chang , Yiwen Guo , Lingfeng Wang , Gaofeng Meng , Shiming Xiang , Chunhong Pan

The progression of chronic diseases often follows highly variable trajectories, and the underlying factors remain poorly understood. Standard mixed-effects models typically represent inter-patient differences as random deviations around a…

Cystic fibrosis is a genetic disease which may appear in early life with structural abnormalities in lung tissues. We propose to detect these abnormalities using a texture classification approach. Our method is a cascade of two…

Computer Vision and Pattern Recognition · Computer Science 2018-03-22 Filipe Marques , Florian Dubost , Mariette Kemner-van de Corput , Harm A. W. Tiddens , Marleen de Bruijne

Histology imaging is an essential diagnosis method to finalize the grade and stage of cancer of different tissues, especially for breast cancer diagnosis. Specialists often disagree on the final diagnosis on biopsy tissue due to the complex…

Computer Vision and Pattern Recognition · Computer Science 2019-09-17 Yongxiang Huang , Albert Chi-shing Chung

Despite the remarkable performance of supervised medical image segmentation models, relying on a large amount of labeled data is impractical in real-world situations. Semi-supervised learning approaches aim to alleviate this challenge using…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yunyao Lu , Yihang Wu , Ahmad Chaddad , Tareef Daqqaq , Reem Kateb

Choosing appropriate hyperparameters for unsupervised clustering algorithms in an optimal way depending on the problem under study is a long standing challenge, which we tackle while adapting clustering algorithms for immune disorder…

Quantitative Methods · Quantitative Biology 2020-09-25 A. Carpio , A. Simón , L. F. Villa

Unsupervised image segmentation aims at assigning the pixels with similar feature into a same cluster without annotation, which is an important task in computer vision. Due to lack of prior knowledge, most of existing model usually need to…

Computer Vision and Pattern Recognition · Computer Science 2020-12-17 Zhichao Wu , Lei Guo , Hao Zhang , Dan Xu