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RNA interference (RNAi) is a mechanism whereby small RNAs (siRNAs) directly control gene expression without assistance from proteins. This mechanism consists of interactions between RNAs and small RNAs both of which may be single or double…

Logic in Computer Science · Computer Science 2012-11-20 Masahiro Hamano

Noise plays a fundamental role in a wide variety of physical and biological dynamical systems. It can arise from an external forcing or due to random dynamics internal to the system. It is well established that even weak noise can result in…

Analysis of PDEs · Mathematics 2019-08-06 Eric Forgoston , Richard O. Moore

We present here a short review of mainly experimental properties of noise as disordered systems are driven into non-ohmic regimes by applying voltages of few volts only. It is found that the noise does not simply follow the resistance in…

Other Condensed Matter · Physics 2009-11-11 K. K. Bardhan , C. D. Mukherjee , U. N. Nandi

Chaos control techniques have been applied to a wide variety of experimental systems, including magneto-elastic ribbons, lasers, chemical reactions, arrhythmic cardiac tissue, and spontaneously bursting neuronal networks. An underlying…

chao-dyn · Physics 2008-02-03 David J. Christini , James J. Collins

Instead of treating the noise as a detrimental effect, can we use it as an information carrier? In this letter, we provide the conceptual and mathematical foundations of wireless communication utilizing noise and random signals in general.…

Information Theory · Computer Science 2023-12-22 Ertugrul Basar

Deep neural networks have shown promise for music audio signal processing applications, often surpassing prior approaches, particularly as end-to-end models in the waveform domain. Yet results to date have tended to be constrained by low…

Audio and Speech Processing · Electrical Eng. & Systems 2020-06-11 William Mitchell , Scott H. Hawley

Noise appears in the brain due to various sources, such as ionic channel fluctuations and synaptic events. They affect the activities of the brain and influence neuron action potentials. Stochastic differential equations have been used to…

Neurons and Cognition · Quantitative Biology 2020-06-01 P R Protachevicz , M S Santos , E G Seifert , E C Gabrick , F S Borges , R R Borges , J Trobia , J D Szezech , K C Iarosz , I L Caldas , C G Antonopoulos , Y Xu , R L Viana , A M Batista

Most microorganisms regulate their cell size. We review here some of the mathematical formulations of the problem of cell size regulation. We focus on coarse-grained stochastic models and the statistics they generate. We review the…

Cell Behavior · Quantitative Biology 2018-01-03 Po-Yi Ho , Jie Lin , Ariel Amir

In recent literature there has been a lot of interest in the phenomena of noise induced transport in the absence of an average bias occurring in spatially periodic systems far from equilibrium. One of the main motivations in this area is to…

Biological Physics · Physics 2007-05-23 Raishma Krishnan , A. M. Jayannavar

Many systems neuroscientists want to understand neurons in terms of mediation; we want to understand how neurons are involved in the causal chain from stimulus to behavior. Unfortunately, most tools are inappropriate for that while our…

Neurons and Cognition · Quantitative Biology 2020-09-04 Ilenna Simone Jones , Konrad Paul Kording

Diffusion models have achieved remarkable success across a wide range of generative tasks, yet their training paradigm largely treats injected noise as uniformly informative. In this work, we challenge this assumption and introduce…

Learning and decision making in the brain are key processes critical to survival, and yet are processes implemented by non-ideal biological building blocks which can impose significant error. We explore quantitatively how the brain might…

Neurons and Cognition · Quantitative Biology 2011-04-19 Jake Bouvrie , Jean-Jacques Slotine

The movement of single kinesin molecules was observed while applying noisy external forces that mimic intracellular active fluctuations. We found kinesin accelerates under noise, especially when a large hindering load is added. The behavior…

Biological Physics · Physics 2021-11-02 Takayuki Ariga , Keito Tateishi , Michio Tomishige , Daisuke Mizuno

Deep neural networks unlocked a vast range of new applications by solving tasks of which many were previously deemed as reserved to higher human intelligence. One of the developments enabling this success was a boost in computing power…

Neural and Evolutionary Computing · Computer Science 2021-12-17 Nadezhda Semenova , Laurent Larger , Daniel Brunner

This paper has two messages. First, we demonstrate that neural networks that process noisy data can learn to exploit, when available, access to auxiliary noise that is correlated with the noise on the data. In effect, the network learns to…

Quantum Physics · Physics 2020-09-17 Aida Ahmadzadegan , Petar Simidzija , Ming Li , Achim Kempf

Based on the measurements of noise in gene expression performed during the last decade, it has become customary to think of gene regulation in terms of a two-state model, where the promoter of a gene can stochastically switch between an ON…

Molecular Networks · Quantitative Biology 2015-06-16 Georg Rieckh , Gašper Tkačik

For several years, numerous attempts have been made to reduce noise and artifacts in MRI. Although there have been many successful methods to address these problems, practical implementation for clinical images is still challenging because…

Image and Video Processing · Electrical Eng. & Systems 2020-03-02 Daiki Tamada

Inside individual cells, expression of genes is stochastic across organisms ranging from bacterial to human cells. A ubiquitous feature of stochastic expression is burst-like synthesis of gene products, which drives considerable…

Molecular Networks · Quantitative Biology 2016-09-13 Pavol Bokes , Abhyudai Singh

One major challenge for living cells is the measurement and prediction of signals corrupted by noise. In general, cells need to make decisions based on their compressed representation of noisy, time-varying signals. Strategies for signal…

Quantitative Methods · Quantitative Biology 2023-07-07 Jenny Poulton , Age Tjalma , Lotte Slim , Pieter Rein ten Wolde

MicroRNAs (miRs) are robust regulators of gene expression, implicated in most biological processes. microRNAs predominantly downregulate the expression of genes post-transcriptionally and each miR is predicted to target several hundred…