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Predictive coding has emerged as an influential normative model of neural computation, with numerous extensions and applications. As such, much effort has been put into mapping PC faithfully onto the cortex, but there are issues that remain…

Neurons and Cognition · Quantitative Biology 2023-03-07 Siavash Golkar , Tiberiu Tesileanu , Yanis Bahroun , Anirvan M. Sengupta , Dmitri B. Chklovskii

Non-reciprocal interactions are a defining feature of many complex systems, biological, ecological, and technological, often pushing them far from equilibrium and enabling rich dynamical responses. These asymmetries can arise at multiple…

Biological Physics · Physics 2026-02-17 Anna Poggialini , Serena Di Santo , Pablo Villegas , Andrea Gabrielli , Miguel A. Muñoz

Neural population activity relating to behaviour is assumed to be inherently low-dimensional despite the observed high dimensionality of data recorded using multi-electrode arrays. Therefore, predicting behaviour from neural population…

Neurons and Cognition · Quantitative Biology 2022-02-17 Justin Jude , Matthew G Perich , Lee E Miller , Matthias H Hennig

Anatomic connections between brain areas affect information flow between neuronal circuits and the synchronization of neuronal activity. However, such structural connectivity does not coincide with effective connectivity, related to the…

Neurons and Cognition · Quantitative Biology 2015-06-03 Demian Battaglia , Annette Witt , Fred Wolf , Theo Geisel

Collective organization in physical, biophysical, and biological systems often emerges from many weak, local interactions, yet the resulting global structures display striking regularities and apparent limits in diversity. Existing…

Physics and Society · Physics 2026-01-21 Arturo Tozzi

Our theoretical understanding of deep learning has not kept pace with its empirical success. While network architecture is known to be critical, we do not yet understand its effect on learned representations and network behavior, or how…

Machine Learning · Computer Science 2022-07-22 Andrew M. Saxe , Shagun Sodhani , Sam Lewallen

Large collections of high-dimensional data have become nearly ubiquitous across many academic fields and application domains, ranging from biology to the humanities. Since working directly with high-dimensional data poses challenges, the…

The traditional view of neural computation in the cerebral cortex holds that sensory neurons are specialized, i.e., selective for certain dimensions of sensory stimuli. This view was challenged by evidence of contextual interactions between…

Neurons and Cognition · Quantitative Biology 2022-04-26 Sergei Gepshtein , Ambarish Pawar , Sunwoo Kwon , Sergey Savel'ev , Thomas D. Albright

Modeling brain dynamics to better understand and control complex behaviors underlying various cognitive brain functions are of interests to engineers, mathematicians, and physicists from the last several decades. With a motivation of…

Neurons and Cognition · Quantitative Biology 2019-08-21 Benjamin Plaster , Gautam Kumar

Neural circuits exhibit structured connectivity, including an overrepresentation of reciprocal connections between neuron pairs. Despite important advances, a full understanding of how such partial symmetry in connectivity shapes neural…

We propose a probabilistic framework for developing computational models of biological neural systems. In this framework, physiological recordings are viewed as discrete-time partial observations of an underlying continuous-time stochastic…

Neurons and Cognition · Quantitative Biology 2026-02-10 Ahmed ElGazzar , Marcel van Gerven

A central challenge in the computational modeling of neural dynamics is the trade-off between accuracy and simplicity. At the level of individual neurons, nonlinear dynamics are both experimentally established and essential for neuronal…

Meta-population networks are effective tools for capturing population movement across distinct regions, but the assumption of well-mixed regions fails to capture the reality of population higher-order interactions. As a multidimensional…

Physics and Society · Physics 2024-06-18 Yanyi Nie , Yanbing Liu , Qixuan Cao , Tao Lin , Wei Wang

We propose a novel framework for learning a low-dimensional representation of data based on nonlinear dynamical systems, which we call dynamical dimension reduction (DDR). In the DDR model, each point is evolved via a nonlinear flow towards…

Machine Learning · Statistics 2022-04-19 Ryeongkyung Yoon , Braxton Osting

Deep learning algorithms demonstrate a surprising ability to learn high-dimensional tasks from limited examples. This is commonly attributed to the depth of neural networks, enabling them to build a hierarchy of abstract, low-dimensional…

Machine Learning · Computer Science 2024-07-04 Francesco Cagnetta , Leonardo Petrini , Umberto M. Tomasini , Alessandro Favero , Matthieu Wyart

We detail how incorporating physics into neural network design can significantly improve the learning and forecasting of dynamical systems, even nonlinear systems of many dimensions. A map building perspective elucidates the superiority of…

Neural and Evolutionary Computing · Computer Science 2020-08-11 Scott T. Miller , John F. Lindner , Anshul Choudhary , Sudeshna Sinha , William L. Ditto

Biological neural networks are notoriously hard to model due to their stochastic behavior and high dimensionality. We tackle this problem by constructing a dynamical model of both the expectations and covariances of the fractions of active…

Neurons and Cognition · Quantitative Biology 2025-02-25 Vincent Painchaud , Patrick Desrosiers , Nicolas Doyon

Integrating functions on discrete domains into neural networks is key to developing their capability to reason about discrete objects. But, discrete domains are (1) not naturally amenable to gradient-based optimization, and (2) incompatible…

Machine Learning · Computer Science 2022-11-15 Nikolaos Karalias , Joshua Robinson , Andreas Loukas , Stefanie Jegelka

From critical infrastructure, to physiology and the human brain, complex systems rarely occur in isolation. Instead, the functioning of nodes in one system often promotes or suppresses the functioning of nodes in another. Despite advances…

Statistical Mechanics · Physics 2019-02-20 Michael M. Danziger , Ivan Bonamassa , Stefano Boccaletti , Shlomo Havlin

The dynamics of neuron populations commonly evolve on low-dimensional manifolds. Thus, we need methods that learn the dynamical processes over neural manifolds to infer interpretable and consistent latent representations. We introduce a…

Machine Learning · Computer Science 2025-01-31 Adam Gosztolai , Robert L. Peach , Alexis Arnaudon , Mauricio Barahona , Pierre Vandergheynst
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