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A novel approach for dealing with censored competing risks regression data is proposed. This is implemented by a mixture of accelerated failure time (AFT) models for a competing risks scenario within a cluster-weighted modelling (CWM)…

Methodology · Statistics 2013-12-04 Utkarsh J. Dang , Paul D. McNicholas

The accelerated failure time (AFT) models have proved useful in many contexts, though heavy censoring (as for example in cancer survival) and high dimensionality (as for example in microarray data) cause difficulties for model fitting and…

Methodology · Statistics 2013-12-10 Md Hasinur Rahaman Khan , J. Ewart H. Shaw

Epidemiological investigations of regionally aggregated spatial data often involve detecting spatial health disparities among neighboring regions on a map of disease mortality or incidence rates. Analyzing such data introduces spatial…

Methodology · Statistics 2025-11-21 Kyle Lin Wu , Sudipto Banerjee

The main objective of accelerated life tests (ALTs) is to predict fraction failings of products in the field. However, there are often discrepancies between the predicted fraction failing from the lab testing data and that from the field…

Applications · Statistics 2014-01-13 Zhi-Sheng Ye , Yili Hong , Yimeng Xie

For many complex diseases, prognosis is of essential importance. It has been shown that, beyond the main effects of genetic (G) and environmental (E) risk factors, the gene-environment (G$\times$E) interactions also play a critical role. In…

Applications · Statistics 2015-05-15 Hao Chai , Qingzhao Zhang , Yu Jiang , Guohua Wang , Sanguo Zhang , Shuangge Ma

We propose an iterative variable selection method for the accelerated failure time model using high-dimensional survival data. Our method pioneers the use of the recently proposed structured screen-and-select framework for survival…

Methodology · Statistics 2025-03-04 Nilotpal Sanyal

A comprehensive, unified approach to modeling arbitrarily censored spatial survival data is presented for the three most commonly-used semiparametric models: proportional hazards, proportional odds, and accelerated failure time. Unlike many…

Applications · Statistics 2017-07-04 Haiming Zhou , Timothy Hanson

This paper considers robust modeling of the survival time for cancer patients. Accurate prediction can be helpful for developing therapeutic and care strategies. We propose a unified Expectation-Maximization approach combined with the…

Methodology · Statistics 2019-12-23 Yi Li , Muxuan Liang , Lu Mao , Sijian Wang

We develop a constructive approach for $\ell_0$-penalized estimation in the sparse accelerated failure time (AFT) model with high-dimensional covariates. Our proposed method is based on Stute's weighted least squares criterion combined with…

Methodology · Statistics 2020-02-11 Xingdong Feng , Jian Huang , Yuling Jiao , Shuang Zhang

The log-logistic regression model is one of the most commonly used accelerated failure time (AFT) models in survival analysis, for which statistical inference methods are mainly established under the frequentist framework. Recently,…

Methodology · Statistics 2023-10-11 Chengqian Xian , Camila P. E. de Souza , Wenqing He , Felipe F. Rodrigues , Renfang Tian

The instability in the selection of models is a major concern with data sets containing a large number of covariates. We focus on stability selection which is used as a technique to improve variable selection performance for a range of…

Methodology · Statistics 2016-04-26 Md Hasinur Rahaman Khan , Anamika Bhadra , Tamanna Howlader

The integration of longitudinal measurements and survival time in statistical modeling offers a powerful framework for capturing the interplay between these two essential outcomes, particularly when they exhibit associations. However, in…

Methodology · Statistics 2025-02-11 Taban Baghfalaki , Mojtaba Ganjali , Rui Martins

Fitting spatio-temporal models for areal data is crucial in many fields such as cancer epidemiology. However, when data sets are very large, many issues arise. The main objective of this paper is to propose a general procedure to analyze…

Methodology · Statistics 2023-02-06 E. Orozco-Acosta , A. Adin , M. D. Ugarte

Recent advances in causal mediation analysis have formalized conditions for estimating direct and indirect effects in various contexts. These approaches have been extended to a number of models for survival outcomes including accelerated…

Methodology · Statistics 2017-01-11 Isabel R. Fulcher , Eric Tchetgen Tchetgen , Paige L. Williams

Survival analysis is a statistical framework for modeling time-to-event data, particularly valuable in healthcare for predicting outcomes like patient discharge or recurrence. This study implements and compares several survival models -…

In this paper, we introduce a new spatial model that incorporates heteroscedastic variance depending on neighboring locations. The proposed process is regarded as the spatial equivalent to the temporal autoregressive conditional…

Statistics Theory · Mathematics 2020-10-20 Philipp Otto , Wolfgang Schmid , Robert Garthoff

We introduce new methods of analysing time to event data via extended versions of the proportional hazards and accelerated failure time (AFT) models. In many time to event studies, the time of first observation is arbitrary, in the sense…

Methodology · Statistics 2011-02-14 Matthew Sperrin , Iain Buchan

Accelerated failure time (AFT) models provide a direct and interpretable time-scale description of covariate effects in lifetime data analysis, but classical formulations rely on linear predictors and are therefore limited in their ability…

Machine Learning · Statistics 2026-03-20 Mebin Jose , Jisha Francis , Sudheesh Kumar Kattumannil

We propose the spatial-temporal aggregated predictor (STAP) modeling framework to address measurement and estimation issues that arise when assessing the relationship between built environment features (BEF) and health outcomes. Many BEFs…

Methodology · Statistics 2021-05-25 Adam Peterson , Jana Hirsch , Brisa Sanchez

Relative survival represents the preferred framework for the analysis of population cancer survival data. The aim is to model the survival probability associated to cancer in the absence of information about the cause of death. Recent data…