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Molecular docking is a major element in drug discovery and design. It enables the prediction of ligand-protein interactions by simulating the binding of small molecules to proteins. Despite the availability of numerous docking algorithms,…

Biomolecules · Quantitative Biology 2024-11-20 Yiliang Yuan , Mustafa Misir

New contributors often struggle to find tasks that they can tackle when onboarding onto a new Open Source Software (OSS) project. One reason for this difficulty is that issue trackers lack explanations about the knowledge or skills needed…

Despite significant progress in multimodal large language models (MLLMs), their performance on complex, multi-page document comprehension remains inadequate, largely due to the lack of high-quality, document-level datasets. While current…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Yuchen Duan , Zhe Chen , Yusong Hu , Weiyun Wang , Shenglong Ye , Botian Shi , Lewei Lu , Qibin Hou , Tong Lu , Hongsheng Li , Jifeng Dai , Wenhai Wang

Speculative decoding (SD) accelerates large language model inference by employing a faster draft model for generating multiple tokens, which are then verified in parallel by the larger target model, resulting in the text generated according…

Math informational retrieval (MIR) search engines are absent in the wide-spread production use, even though documents in the STEM fields contain many mathematical formulae, which are sometimes more important than text for understanding. We…

Digital Libraries · Computer Science 2021-07-15 Dávid Lupták , Vít Novotný , Michal Štefánik , Petr Sojka

Domain experts are increasingly employing machine learning to solve their domain-specific problems. This article presents six key challenges that a domain expert faces in transforming their problem into a computational workflow, and then…

Software Engineering · Computer Science 2023-12-27 Bentley James Oakes , Michalis Famelis , Houari Sahraoui

An essential part of software maintenance and evolution, refactoring is performed by developers, regardless of technology or domain, to improve the internal quality of the system, and reduce its technical debt. However, choosing the…

Software Engineering · Computer Science 2021-10-26 Anthony Peruma , Steven Simmons , Eman Abdullah AlOmar , Christian D. Newman , Mohamed Wiem Mkaouer , Ali Ouni

In open-source projects, anyone can contribute, so it is important to have an active continuous integration and continuous delivery (CI/CD) pipeline in addition to a protocol for reporting security concerns, especially in projects that are…

Software Engineering · Computer Science 2023-10-16 Jessy Ayala , Joshua Garcia

Enhancing small language models for real-life application deployment is a significant challenge facing the research community. Due to the difficulties and costs of using large language models, researchers are seeking ways to effectively…

Computation and Language · Computer Science 2024-09-20 Mohamad Ballout , Ulf Krumnack , Gunther Heidemann , Kai-Uwe Kühnberger

Comparative evaluation of several systems is a recurrent task in researching. It is a key step before deciding which system to use for our work, or, once our research has been conducted, to demonstrate the potential of the resulting model.…

Computation and Language · Computer Science 2026-02-24 Sergio Gómez González , Miguel Domingo , Francisco Casacuberta

LLMs have garnered considerable attention for their potential to streamline Automated Program Repair (APR). LLM-based approaches can either insert the correct code or directly generate patches when provided with buggy methods. However, most…

Software Engineering · Computer Science 2025-09-30 Qiong Feng , Xiaotian Ma , Jiayi Sheng , Ziyuan Feng , Wei Song , Peng Liang

Machine Learning (ML) is increasingly being adopted in different industries. Deep Reinforcement Learning (DRL) is a subdomain of ML used to produce intelligent agents. Despite recent developments in DRL technology, the main challenges that…

Software Engineering · Computer Science 2024-05-21 Mohammad Mehdi Morovati , Florian Tambon , Mina Taraghi , Amin Nikanjam , Foutse Khomh

Foundation models are trained on increasingly immense and opaque datasets. Even while these models are now key in AI system building, it can be difficult to answer the straightforward question: has the model already encountered a given…

Machine Learning · Computer Science 2023-12-15 Marc Marone , Benjamin Van Durme

Modern code review is a widely used technique employed in both industrial and open-source projects to improve software quality, share knowledge, and ensure adherence to coding standards and guidelines. During code review, developers may…

Software Engineering · Computer Science 2022-03-29 Eman Abdullah AlOmar , Moataz Chouchen , Mohamed Wiem Mkaouer , Ali Ouni

Deep learning (DL) applications, built upon a heterogeneous and complex DL stack (e.g., Nvidia GPU, Linux, CUDA driver, Python runtime, and TensorFlow), are subject to software and hardware dependencies across the DL stack. One challenge in…

Software Engineering · Computer Science 2023-09-04 Kaifeng Huang , Bihuan Chen , Susheng Wu , Junmin Cao , Lei Ma , Xin Peng

Input constraints are useful for many software development tasks. For example, input constraints of a function enable the generation of valid inputs, i.e., inputs that follow these constraints, to test the function deeper. API functions of…

Software Engineering · Computer Science 2024-03-07 Danning Xie , Yitong Li , Mijung Kim , Hung Viet Pham , Lin Tan , Xiangyu Zhang , Michael W. Godfrey

Unstructured text has long been difficult to automatically analyze at scale. Large language models (LLMs) now offer a way forward by enabling {\em semantic data processing}, where familiar data processing operators (e.g., map, reduce,…

Human-Computer Interaction · Computer Science 2025-04-22 Shreya Shankar , Bhavya Chopra , Mawil Hasan , Stephen Lee , Björn Hartmann , Joseph M. Hellerstein , Aditya G. Parameswaran , Eugene Wu

The problem of software artifact retrieval has the goal to effectively locate software artifacts, such as a piece of source code, in a large code repository. This problem has been traditionally addressed through the textual query. In other…

Machine Learning · Computer Science 2016-11-15 Liang Wu , Hui Xiong , Liang Du , Bo Liu , Guandong Xu , Yong Ge , Yanjie Fu , Yuanchun Zhou , Jianhui Li

Data visualizations are central to scientific communication, journalism, and everyday decision-making, yet they are frequently prone to errors that can distort interpretation or mislead audiences. Rule-based visualization linters can flag…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Valentin Bonas , Martin Sinnona , Viviana Siless , Emmanuel Iarussi

Declarative process modeling formalisms - which capture high-level process constraints - have seen growing interest, especially for modeling flexible processes. This paper presents DisCoveR, an extremely efficient and accurate declarative…

Machine Learning · Computer Science 2020-05-21 Christoffer Olling Back , Tijs Slaats , Thomas Troels Hildebrandt , Morten Marquard
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