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A common problem in health research is that we have a large database with many variables measured on a large number of individuals. We are interested in measuring additional variables on a subsample; these measurements may be newly…

Methodology · Statistics 2022-03-22 Thomas Lumley , Tong Chen

Selecting relevant features associated with a given response variable is an important issue in many scientific fields. Quantifying quality and uncertainty of a selection result via false discovery rate (FDR) control has been of recent…

Methodology · Statistics 2020-12-17 Chenguang Dai , Buyu Lin , Xin Xing , Jun S. Liu

Traditional GWAS has advanced our understanding of complex diseases but often misses nonlinear genetic interactions. Deep learning offers new opportunities to capture complex genomic patterns, yet existing methods mostly depend on feature…

Machine Learning · Computer Science 2025-07-08 Iqra Farooq , Sara Atito , Ayse Demirkan , Inga Prokopenko , Muhammad Rana

We propose a compressive classification framework for settings where the data dimensionality is significantly higher than the sample size. The proposed method, referred to as compressive regularized discriminant analysis (CRDA) is based on…

Machine Learning · Statistics 2020-11-13 Muhammad Naveed Tabassum , Esa Ollila

The early detection of pancreatic neoplasm is a major clinical dilemma, and it is predominantly so because tumors are likely to occur with minimal contrast margins and a large spread anatomy-wide variation amongst patients on a CT scan.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 Janani Annur Thiruvengadam , Kiran Mayee Nabigaru , Anusha Kovi

We consider a model of unreliable or crowdsourced data where there is an underlying set of $n$ binary variables, each evaluator contributes a (possibly unreliable or adversarial) estimate of the values of some subset of $r$ of the…

Machine Learning · Computer Science 2017-08-10 Michela Meister , Gregory Valiant

Feature selection is an important process in machine learning. It builds an interpretable and robust model by selecting the features that contribute the most to the prediction target. However, most mature feature selection algorithms,…

Machine Learning · Computer Science 2022-07-20 Zhifeng Qiu , Wanxin Zeng , Dahua Liao , Ning Gui

In machine learning, the process of feature selection involves finding a reduced subset of features that captures most of the information required to train an accurate and efficient model. This work presents FeatureCuts, a novel feature…

Machine Learning · Computer Science 2025-08-05 Andy Hu , Devika Prasad , Luiz Pizzato , Nicholas Foord , Arman Abrahamyan , Anna Leontjeva , Cooper Doyle , Dan Jermyn

We investigate the problem of fitting piecewise affine functions (PWA) to data. Our algorithm divides the input domain into finitely many polyhedral regions whose shapes are specified using a user-defined template such that the data points…

Systems and Control · Electrical Eng. & Systems 2024-11-20 Guillaume O. Berger , Sriram Sankaranarayanan

In this paper, we study high-dimensional sparse Quadratic Discriminant Analysis (QDA) and aim to establish the optimal convergence rates for the classification error. Minimax lower bounds are established to demonstrate the necessity of…

Methodology · Statistics 2019-12-09 T. Tony Cai , Linjun Zhang

We revisit the problem of feature selection in linear discriminant analysis (LDA), that is, when features are correlated. First, we introduce a pooled centroids formulation of the multiclass LDA predictor function, in which the relative…

Applications · Statistics 2010-10-11 Miika Ahdesmäki , Korbinian Strimmer

The complexity of semiparametric models poses new challenges to statistical inference and model selection that frequently arise from real applications. In this work, we propose new estimation and variable selection procedures for the…

Statistics Theory · Mathematics 2011-03-09 Bo Kai , Runze Li , Hui Zou

Feature selection (FS) is an important research topic in machine learning. Usually, FS is modelled as a+ bi-objective optimization problem whose objectives are: 1) classification accuracy; 2) number of features. One of the main issues in…

Artificial Intelligence · Computer Science 2021-04-21 Yu Xue , Yihang Tang , Xin Xu , Jiayu Liang , Ferrante Neri

Because of high dimensionality, correlation among covariates, and noise contained in data, dimension reduction (DR) techniques are often employed to the application of machine learning algorithms. Principal Component Analysis (PCA), Linear…

Machine Learning · Statistics 2019-10-08 Katherine C. Kempfert , Yishi Wang , Cuixian Chen , Samuel W. K. Wong

Presently the most successful approaches to semi-supervised learning are based on consistency regularization, whereby a model is trained to be robust to small perturbations of its inputs and parameters. To understand consistency…

Machine Learning · Computer Science 2019-02-22 Ben Athiwaratkun , Marc Finzi , Pavel Izmailov , Andrew Gordon Wilson

In this paper, a new descriptor selection method for selecting an optimal combination of important descriptors of sulfonamide derivatives data, named self tuned reweighted sampling (STRS), is developed. descriptors are defined as the…

Machine Learning · Computer Science 2014-02-24 Doreswamy , Chanabasayya M. Vastrad

Introduction The focus of analyzing data from microarray experiments and extracting biological insight from such data has experienced a shift from identification of individual genes in association with a phenotype to that of biological…

Genomics · Quantitative Biology 2015-08-10 Lei Zhang , Linlin Wang , Pu Tian , Suyan Tian

Averaging iterations of Stochastic Gradient Descent (SGD) have achieved empirical success in training deep learning models, such as Stochastic Weight Averaging (SWA), Exponential Moving Average (EMA), and LAtest Weight Averaging (LAWA).…

Machine Learning · Computer Science 2024-11-21 Peng Wang , Li Shen , Zerui Tao , Yan Sun , Guodong Zheng , Dacheng Tao

In this paper, we aim to develop a simple and scalable reinforcement learning algorithm that uses standard supervised learning methods as subroutines. Our goal is an algorithm that utilizes only simple and convergent maximum likelihood loss…

Machine Learning · Computer Science 2019-10-09 Xue Bin Peng , Aviral Kumar , Grace Zhang , Sergey Levine

Although much progress has been made in classification with high-dimensional features \citep{Fan_Fan:2008, JGuo:2010, CaiSun:2014, PRXu:2014}, classification with ultrahigh-dimensional features, wherein the features much outnumber the…

Machine Learning · Statistics 2016-11-14 Yanming Li , Hyokyoung Hong , Jian Kang , Kevin He , Ji Zhu , Yi Li
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