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Related papers: FPGA Acceleration of Sequence Alignment: A Survey

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Computational complexity is a key limitation of genomic analyses. Thus, over the last 30 years, researchers have proposed numerous fast heuristic methods that provide computational relief. Comparing genomic sequences is one of the most…

Edge computing devices inherently face tight resource constraints, which is especially apparent when deploying Deep Neural Networks (DNN) with high memory and compute demands. FPGAs are commonly available in edge devices. Since these…

Hardware Architecture · Computer Science 2021-10-04 Jude Haris , Perry Gibson , José Cano , Nicolas Bohm Agostini , David Kaeli

Multiple Sequence Alignment (MSA) is one of the most computationally intensive tasks in Computational Biology. Existing best known solutions for multiple sequence alignment take several hours (in some cases days) of computation time to…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-01-20 Fahad Saeed , Ashfaq Khokhar

Graph neural network (GNN) inference faces significant bottlenecks in preprocessing, which often dominate overall inference latency. We introduce AutoGNN, an FPGA-based accelerator designed to address these challenges by leveraging FPGA's…

Genetic Programming (GP), an evolutionary learning technique, has multiple applications in machine learning such as curve fitting, data modelling, feature selection, classification etc. GP has several inherent parallel steps, making it an…

Neural and Evolutionary Computing · Computer Science 2021-10-22 Vimarsh Sathia , Venkataramana Ganesh , Shankara Rao Thejaswi Nanditale

Recent technological advances in Next Generation Sequencing tools have led to increasing speeds of DNA sample collection, preparation, and sequencing. One instrument can produce over 600 Gb of genetic sequence data in a single run. This…

Quantitative Methods · Quantitative Biology 2016-11-18 Stephanie Dodson , Darrell O. Ricke , Jeremy Kepner

Genomic data sets are growing dramatically as the cost of sequencing continues to decline and small sequencing devices become available. Enormous community databases store and share this data with the research community, but some of these…

Neural architectures and hardware accelerators have been two driving forces for the progress in deep learning. Previous works typically attempt to optimize hardware given a fixed model architecture or model architecture given fixed…

There is a large body of legacy scientific code written in languages like Fortran that is not optimised to get the best performance out of heterogeneous acceleration devices like GPUs and FPGAs, and manually porting such code into parallel…

Performance · Computer Science 2019-01-25 Wim Vanderbauwhede , Syed Waqar Nabi

Deep neural networks have evolved remarkably over the past few years and they are currently the fundamental tools of many intelligent systems. At the same time, the computational complexity and resource consumption of these networks also…

Computer Vision and Pattern Recognition · Computer Science 2018-02-13 Jian Cheng , Peisong Wang , Gang Li , Qinghao Hu , Hanqing Lu

The search for similar genetic sequences is one of the main bioinformatics tasks. The genetic sequences data banks are growing exponentially and the searching techniques that use linear time are not capable to do the search in the required…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-07-13 Felipe Albrecht

Genome sequence alignment is the core of many biological applications. The advancement of sequencing technologies produces a tremendous amount of data, making sequence alignment a critical bottleneck in bioinformatics analysis. The existing…

Hardware Architecture · Computer Science 2023-01-26 Weihong Xu , Saransh Gupta , Niema Moshiri , Tajana Rosing

Recurrent Neural Networks (RNNs) are vital for sequential data processing. Long Short-Term Memory Autoencoders (LSTM-AEs) are particularly effective for unsupervised anomaly detection in time-series data. However, inherent sequential…

Hardware Architecture · Computer Science 2026-03-17 Aimilios Leftheriotis , Dimosthenis Masouros , Dimitrios Soudris , George Theodoridis

AI acceleration has been dominated by GPUs, but the growing need for lower latency, energy efficiency, and fine-grained hardware control exposes the limits of fixed architectures. In this context, Field-Programmable Gate Arrays (FPGAs)…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-18 Arturo Urías Jiménez

DNA sequencing is the physical/biochemical process of identifying the location of the four bases (Adenine, Guanine, Cytosine, Thymine) in a DNA strand. As semiconductor technology revolutionized computing, modern DNA sequencing technology…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-05-06 S. Karen Khatamifard , Zamshed Chowdhury , Nakul Pande , Meisam Razaviyayn , Chris Kim , Ulya R. Karpuzcu

Recent trends in business and technology (e.g., machine learning, social network analysis) benefit from storing and processing growing amounts of graph-structured data in databases and data science platforms. FPGAs as accelerators for graph…

Databases · Computer Science 2021-02-09 Jonas Dann , Daniel Ritter , Holger Fröning

Recent researches on robotics have shown significant improvement, spanning from algorithms, mechanics to hardware architectures. Robotics, including manipulators, legged robots, drones, and autonomous vehicles, are now widely applied in…

Robotics · Computer Science 2021-03-08 Zishen Wan , Bo Yu , Thomas Yuang Li , Jie Tang , Yuhao Zhu , Yu Wang , Arijit Raychowdhury , Shaoshan Liu

Motivation: Next-generation sequencing tools have enabled producing of huge amount of genomic information at low cost. Unfortunately, presence of sequencing errors in such data affects quality of downstream analyzes. Accuracy of them can be…

Genomics · Quantitative Biology 2017-03-03 Maciej Dlugosz , Sebastian Deorowicz

Neural Networks (NN) provide a solid and reliable way of executing different types of applications, ranging from speech recognition to medical diagnosis, speeding up onerous and long workloads. The challenges involved in their…

Hardware Architecture · Computer Science 2023-09-26 Federico Manca , Francesco Ratto

The emergence of artificial intelligence (AI) accelerators like NVIDIA Tensor Cores offers new opportunities to speed up tensor-heavy scientific computations. However, applying them to quantum chemistry is challenging due to strict accuracy…

Chemical Physics · Physics 2026-04-20 Hua Huang , Wenkai Shao , Jeff Hammond
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