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Recurrent Neural Networks (RNNs) are widely used for modelling neural activity, yet the mathematical interplay of core procedures is used to analyze them (temporal rescaling, discretization, and linearization) remain uncharacterized. This…

Neural and Evolutionary Computing · Computer Science 2025-04-08 Mariano Caruso , Cecilia Jarne

Networks of model neurons with balanced recurrent excitation and inhibition produce irregular and asynchronous spiking activity. We extend the analysis of balanced networks to include the known dependence of connection probability on the…

Neurons and Cognition · Quantitative Biology 2014-06-02 Robert Rosenbaum , Brent Doiron

Recurrent Neural Networks (RNNs) were recently successfully used to model the way neural activity drives task-related behavior in animals, operating under the implicit assumption that the obtained solutions are universal. Observations in…

Neurons and Cognition · Quantitative Biology 2021-11-19 Elia Turner , Kabir Dabholkar , Omri Barak

Recurrent neural networks (RNNs) have recently achieved remarkable successes in a number of applications. However, the huge sizes and computational burden of these models make it difficult for their deployment on edge devices. A practically…

Machine Learning · Computer Science 2019-12-10 Liangjian Wen , Xuanyang Zhang , Haoli Bai , Zenglin Xu

Individual neurons often produce highly variable responses over nominally identical trials, reflecting a mixture of intrinsic "noise" and systematic changes in the animal's cognitive and behavioral state. Disentangling these sources of…

Neurons and Cognition · Quantitative Biology 2021-11-08 Alex H. Williams , Scott W. Linderman

Elucidating the neurophysiological mechanisms underlying neural pattern formation remains an outstanding challenge in Computational Neuroscience. In this paper, we address the issue of understanding the emergence of neural patterns by…

Neurons and Cognition · Quantitative Biology 2024-06-04 Gregory Dumont , Carmen Oana Tarniceriu

Solving mixed-integer optimization problems with embedded neural networks with ReLU activation functions is challenging. Big-M coefficients that arise in relaxing binary decisions related to these functions grow exponentially with the…

Optimization and Control · Mathematics 2025-02-06 Christoph Plate , Mirko Hahn , Alexander Klimek , Caroline Ganzer , Kai Sundmacher , Sebastian Sager

Maximum entropy methods provide a principled path connecting measurements of neural activity directly to statistical physics models, and this approach has been successful for populations of $N\sim 100$ neurons. As $N$ increases in new…

Biological Physics · Physics 2023-10-18 Christopher W. Lynn , Qiwei Yu , Rich Pang , William Bialek , Stephanie E. Palmer

The statistics of correlations are central quantities characterizing the collective dynamics of recurrent neural networks. We derive exact expressions for the statistics of correlations of nonlinear recurrent networks in the limit of a…

Neurons and Cognition · Quantitative Biology 2026-04-23 German Mato , Facundo Rigatuso , Gonzalo Torroba

Repeating patterns of spike sequences from a neuronal network have been proposed to be useful in the reconstruction of the network topology. Reverberations in a physiologically realistic model with various physical connection topologies…

Neurons and Cognition · Quantitative Biology 2014-07-15 Hao Song , Chun-Chung Chen , Jyh-Jang Sun , Pik-Yin Lai , C. K. Chan

We address the approximation of entropy solutions to initial-boundary value problems for nonlinear strictly hyperbolic conservation laws using neural networks. A general and systematic framework is introduced for the design of efficient and…

Analysis of PDEs · Mathematics 2025-09-16 Igor Ciril , Khalil Haddaoui , Yohann Tendero

The time elapsed model describes the firing activity of an homogeneous assembly of neurons thanks to the distribution of times elapsed since the last discharge. It gives a mathematical description of the probability density of neurons…

Analysis of PDEs · Mathematics 2011-09-16 Khashayar Pakdaman , Benoît Perthame , Delphine Salort

Brain science is an evolving research area inviting great enthusiasm with its potential for providing insights and thereby, preventing, and treating multiple neuronal disorders affecting millions of patients. Discovery of relationships,…

Neurons and Cognition · Quantitative Biology 2016-03-17 Bisakha Ray , Alexander V. Alekseyenko , Sisi Ma , Alexander Statnikov , Constantin Aliferis

Neurophysiologists are nowadays able to record from a large number of extracellular electrodes and to extract, from the raw data, the sequences of action potentials or spikes generated by many neurons. Unfortunately these ''many neurons''…

Applications · Statistics 2026-04-22 Pierre Charitat , Ségolen Geffray , Christophe Pouzat

To understand cognitive reasoning in the brain, it has been proposed that symbols and compositions of symbols are represented by activity patterns (vectors) in a large population of neurons. Formal models implementing this idea [Plate…

Neural and Evolutionary Computing · Computer Science 2017-07-06 E. Paxon Frady , Denis Kleyko , Friedrich T. Sommer

Here, I present a novel method for normalizing a finite set of numbers, which is studied by the domain of biological vision. Normalizing in this context means searching the maximum and minimum number in a set and then rescaling all numbers…

Adaptation and Self-Organizing Systems · Physics 2007-09-19 Matthias S. Keil

Adaptive robust optimization problems have received significant attention in recent years, but remain notoriously difficult to solve when recourse decisions are discrete in nature. In this paper, we propose new reformulation techniques for…

Optimization and Control · Mathematics 2024-03-29 Merve Bodur , Timothy C. Y. Chan , Ian Yihang Zhu

We consider signal transaction in a simple neuronal model featuring intrinsic noise. The presence of noise limits the precision of neural responses and impacts the quality of neural signal transduction. We assess the signal transduction…

Biological Physics · Physics 2015-03-17 Michael J. Barber , Manfred L. Ristig

Volumetric brain reconstructions provide an unprecedented opportunity to gain insights into the complex connectivity patterns of neurons in an increasing number of organisms. Here, we model and quantify the complexity of the resulting…

Neurons and Cognition · Quantitative Biology 2024-05-13 Anastasiya Salova , István A. Kovács

Far from equilibrium, neural systems self-organize across multiple scales. Exploiting multiscale self-organization in neuroscience and artificial intelligence requires a computational framework for modeling the effective non-equilibrium…

Neurons and Cognition · Quantitative Biology 2025-10-09 Nathan X. Kodama
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