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In this article, we introduce the joint maximum a posteriori state path and parameter estimator (JME) for continuous-time systems described by stochastic differential equations (SDEs). This estimator can be applied to nonlinear systems with…

Statistics Theory · Mathematics 2017-04-07 Dimas Abreu Archanjo Dutra , Bruno Otávio Soares Teixeira , Luis Antonio Aguirre

Assessing the time scale of biological processes using molecular dynamics (MD) simulations with sufficient statistical accuracy is a challenging task, as processes are often rare and/or slow events, which may extend largely beyond the time…

Computational Physics · Physics 2026-02-16 Wouter Vervust , Elias Wils , Sina Safaei , Daniel T. Zhang , An Ghysels

Shortcut to isothermality is a driving strategy to steer the system to its equilibrium states within finite time, and enables evaluating the impact of a control promptly. Finding optimal scheme to minimize the energy cost is of critical…

Statistical Mechanics · Physics 2022-06-14 Geng Li , Jin-Fu Chen , C. P. Sun , Hui Dong

Access to the potential energy Hessian enables determination of the Gibbs free energy, and certain approaches to transition state search and optimization. Here, we demonstrate that off-the-shelf pretrained Open Catalyst Project (OCP)…

Materials Science · Physics 2024-10-08 Brook Wander , Joseph Musielewicz , Raffaele Cheula , John R. Kitchin

Significant effort in applied quantum computing has been devoted to the problem of ground state energy estimation for molecules and materials. Yet, for many applications of practical value, additional properties of the ground state must be…

Quantum Physics · Physics 2022-07-13 Ruizhe Zhang , Guoming Wang , Peter Johnson

We present a scheme to perform an iterative variational optimization with infinite projected entangled-pair states (iPEPS), a tensor network ansatz for a two-dimensional wave function in the thermodynamic limit, to compute the ground state…

Strongly Correlated Electrons · Physics 2017-05-02 Philippe Corboz

One of the most challenging problems in understanding the structural phase transformations in Pu is to determine the energetically favored, continuous atomic pathways from one crystal symmetry to another. This problem involves enumerating…

Materials Science · Physics 2015-05-13 R. Gröger , T. Lookman , A. Saxena

The implementation of QED initial-state radiative corrections in the process of four-fermion production at LEP200 and higher-energy e+e- colliders is discussed. Because of the presence of charged-current processes, this is a nontrivial…

High Energy Physics - Phenomenology · Physics 2009-10-28 F. A. Berends , R. Pittau , R. Kleiss

We present an algorithm for learning mixtures of Markov chains and Markov decision processes (MDPs) from short unlabeled trajectories. Specifically, our method handles mixtures of Markov chains with optional control input by going through a…

Machine Learning · Statistics 2023-02-07 Chinmaya Kausik , Kevin Tan , Ambuj Tewari

To address the problem of combined heat and power economic emission dispatch (CHPEED), a two-stage approach is proposed by combining multi-objective optimization (MOO) with integrated decision making (IDM). First, a practical CHPEED model…

Optimization and Control · Mathematics 2018-08-22 Yang Li , Jinlong Wang , Dongbo Zhao , Guoqing Li , Chen Chen

In this paper, we harness a result in point process theory, specifically the expectation of the weighted $K$-function, where the weighting is done by the true first-order intensity function. This theoretical result can be employed as an…

Methodology · Statistics 2024-03-13 Nicoletta D'Angelo , Giada Adelfio

Spatial prediction is commonly achieved under the assumption of a Gaussian random field (GRF) by obtaining maximum likelihood estimates of parameters, and then using the kriging equations to arrive at predicted values. For massive datasets,…

Methodology · Statistics 2021-07-20 Karl T. Pazdernik , Ranjan Maitra

We show that neural networks can be optimized to represent minimum energy paths as continuous functions, offering a flexible alternative to discrete path-search methods such as Nudged Elastic Band (NEB). Our approach parameterizes reaction…

Machine Learning · Computer Science 2025-07-10 Kalyan Ramakrishnan , Lars L. Schaaf , Chen Lin , Guangrun Wang , Philip Torr

Molecule synthesis through machine learning is one of the fundamental problems in drug discovery. Current data-driven strategies employ one-step retrosynthesis models and search algorithms to predict synthetic routes in a top-bottom manner.…

Machine Learning · Computer Science 2024-06-05 Songtao Liu , Hanjun Dai , Yue Zhao , Peng Liu

Phase equilibrium calculation, also known as flash calculation, plays significant roles in various aspects of petroleum and chemical industries. Since Michelsen proposed his milestone studies in 1982, through several decades of development,…

Computational Physics · Physics 2020-08-11 Yuze Zhang , Yiteng Li , Lei Zhang , Shuyu Sun

Understanding kinetics including reaction pathways and associated transition rates is an important yet difficult problem in numerous chemical and biological systems especially in situations with multiple competing pathways. When these…

Computational Physics · Physics 2021-09-22 Sun-Ting Tsai , Zachary Smith , Pratyush Tiwary

The minimum rate of entropy production (MREP) and the least dissipation energy (LDE) principles are re-examined concerning continuous systems in stationary nonequilibrium states. By means of simple considerations on coefficients of…

Classical Physics · Physics 2009-06-04 M. Salis

Industrial robotics demands significant energy to operate, making energy-reduction methodologies increasingly important. Strategies for planning minimum-energy trajectories typically involve solving nonlinear optimal control problems…

Robotics · Computer Science 2025-01-17 Domenico Dona' , Giovanni Franzese , Cosimo Della Santina , Paolo Boscariol , Basilio Lenzo

I describe the first continuous space nuclear path integral quantum Monte Carlo method, and calculate the ground state properties of light nuclei including Deuteron, Triton, Helium-3 and Helium-4, using both local chiral interaction up to…

Nuclear Theory · Physics 2022-07-19 Rong Chen

We propose a machine-learning approach based on Bayesian optimization to build global potential energy surfaces (PES) for reactive molecular systems using feedback from quantum scattering calculations. The method is designed to correct for…

Chemical Physics · Physics 2019-03-27 R. A. Vargas-Hernández , Y. Guan , D. H. Zhang , R. V. Krems
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