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We propose a computational framework for vascular fluid-structure interaction (FSI), focusing on biomechanical modeling, geometric modeling, and solver technology. The biomechanical model is constructed based on the unified continuum…

Fluid Dynamics · Physics 2022-06-27 Ju Liu , Jiayi Huang , Qingshuang Lu , Yujie Sun

In our recent work, we introduced the reduced unified continuum formulation for vascular fluid-structure interaction (FSI) and demonstrated enhanced solver accuracy, scalability, and performance compared to conventional approaches. We…

Computational Physics · Physics 2022-03-03 Ingrid S. Lan , Ju Liu , Weiguang Yang , Judith Zimmermann , Daniel B. Ennis , Alison L. Marsden

A patient-specific fluid-structure interaction (FSI) model of a phase-contrast magnetic resonance angiography (PC-MRA) imaged arteriovenous fistula is presented. The numerical model is developed and simulated using a commercial multiphysics…

Medical Physics · Physics 2018-01-30 W. P. Guess , B. D. Reddy , A. McBride , B. Spottiswoode , J. Downs , T. Franz

Computational fluid dynamics (CFD) is increasingly used to study blood flows in patient-specific arteries for understanding certain cardiovascular diseases. The techniques work quite well for relatively simple problems, but need…

Computational Physics · Physics 2018-10-11 Fande Kong , Vitaly Kheyfets , Ender Finol , Xiao-Chuan Cai

Fluid-Structure Interaction (FSI) can be investigated by means of non-linear Finite Element Models (FEM), suitable to capture large deflections of structural parts interacting with fluids, and Computational Fluid Dynamics (CFD). High…

We present a new model and a novel loosely coupled partitioned numerical scheme modeling fluid-structure interaction (FSI) in blood flow allowing non-zero longitudinal displacement. Arterial walls are modeled by a {linearly viscoelastic,…

Numerical Analysis · Mathematics 2015-06-05 Martina Bukac , Suncica Canic , Roland Glowinski , Josip Tambaca , Annalisa Quaini

We recently demonstrated the reduction of the unified continuum and variational multiscale formulation to a computationally efficient fluid-structure interaction (FSI) formulation via three sound modeling assumptions pertaining to the…

Medical Physics · Physics 2022-01-12 Ingrid S. Lan , Ju Liu , Weiguang Yang , Alison L. Marsden

We study the impact of using fluid-structure interactions (FSI) to simulate blood flow in a large stenosed artery. We compare typical flow configurations using Navier-Stokes in a rigid geometry setting to a fully coupled FSI model. The…

Computational Physics · Physics 2021-02-01 Lukas Failer , Piotr Minakowski , Thomas Richter

Accurate simulation of blood flow in deformable vessels is critical in cardiovascular research for understanding disease progression and informing clinical decision-making. However, due to the thin-walled nature of arteries, traditional…

Computational Engineering, Finance, and Science · Computer Science 2026-01-05 Chenxi Zhao , Dong Wu , Weiyi Kong , Oskar J. Haidn , Xiangyu Hu

Fluid-structure interaction (FSI) simulation of biological systems presents significant computational challenges, particularly for applications involving large structural deformations and contact mechanics, such as heart valve dynamics.…

Quantitative Methods · Quantitative Biology 2026-02-13 Ryan T. Black , Steve A. Maas , Wensi Wu , Jalaj Maheshwari , Tzanio Kolev , Jeffrey A. Weiss , Matthew A. Jolley

Three-field Fluid-Structure Interaction (FSI) formulations for fluid and solid are applied and compared to the standard two field-one field formulation for fluid and solid, respectively. Both formulations are applied in a non linear setting…

Numerical Analysis · Mathematics 2020-10-13 Alexis Tello , Ramon Codina

We implement full, three-dimensional constrained mixture theory for vascular growth and remodeling into a finite element fluid-structure interaction (FSI) solver. The resulting "fluid-solid-growth" (FSG) solver allows long term,…

Computational Engineering, Finance, and Science · Computer Science 2023-08-11 Erica L. Schwarz , Martin R. Pfaller , Jason M. Szafron , Marcos Latorre , Stephanie E. Lindsey , Christopher K. Breuer , Jay D. Humphrey , Alison L. Marsden

Numerical simulations to evaluate thoracic aortic hemodynamics include a computational fluid dynamic (CFD) approach or fluid-structure interaction (FSI) approach. While CFD neglects the arterial deformation along the cardiac cycle by…

We recently derived the unified continuum and variational multiscale formulation for fluid-structure interaction (FSI) using the Gibbs free energy. Restricting our attention to vascular FSI, we now reduce this arbitrary Lagrangian-Eulerian…

Computational Physics · Physics 2022-04-06 Ingrid S. Lan , Ju Liu , Weiguang Yang , Alison L. Marsden

For problems involving large deformations of thin structures, simulating fluid-structure interaction (FSI) remains challenging largely due to the need to balance computational feasibility, efficiency, and solution accuracy. Overlapping…

Computational Engineering, Finance, and Science · Computer Science 2020-03-18 Maximilian Balmus , Andre Massing , Johan Hoffman , Reza Razavi , David Nordsletten

Fluid-structure interaction (FSI) modeling, a technique widely used to enhance imaging modalities for adult and pediatric heart diseases, has been underutilized in the context of fetal circulation because of limited data on flow conditions…

Medical Physics · Physics 2024-10-29 Zhenglun Alan Wei , Guihong Chen , Biao Si , Liqun Sun , Mike Seed , Shuping Ge

We study a nonlinear, unsteady, moving boundary, fluid-structure interaction (FSI) problem arising in modeling blood flow through elastic and viscoelastic arteries. The fluid flow, which is driven by the time-dependent pressure data, is…

Analysis of PDEs · Mathematics 2015-06-05 Boris Muha , Suncica Canic

Over the past few decades, there has been a rapid improvement in computational power as well as techniques to simulate the real world phenomenon which has enabled us to understand the physics and develop new systems which outperform the…

Computational Physics · Physics 2020-06-09 Sumant R Morab , Atul Sharma

We study a nonlinear, unsteady, moving boundary, fluid-structure (FSI) problem in which the structure is composed of two layers: a thin layer which is in contact with the fluid, and a thick layer which sits on top of the thin structural…

Analysis of PDEs · Mathematics 2013-05-24 Boris Muha , Suncica Canic

We report a novel physics-informed neural framework for reconstructing unsteady fluid-structure interactions (FSI) from sparse, single-phase observations of the flow. Our approach combines a modal surface model with coordinate neural…

Fluid Dynamics · Physics 2026-04-07 Rui Tang , Ke Zhou , Jifu Tan , Samuel J. Grauer
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