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Nuclei appear small in size, yet, in real clinical practice, the global spatial information and correlation of the color or brightness contrast between nuclei and background, have been considered a crucial component for accurate nuclei…

Image and Video Processing · Electrical Eng. & Systems 2023-07-18 Zhenqi He , Mathias Unberath , Jing Ke , Yiqing Shen

Modern histopathological image analysis relies on the segmentation of cell structures to derive quantitative metrics required in biomedical research and clinical diagnostics. State-of-the-art deep learning approaches predominantly apply…

Image and Video Processing · Electrical Eng. & Systems 2022-01-12 Yoav Alon , Huiyu Zhou

Accurate segmentation of anatomical structures and abnormalities in medical images is crucial for computer-aided diagnosis and analysis. While deep learning techniques excel at this task, their computational demands pose challenges.…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Syed Javed , Tariq M. Khan , Abdul Qayyum , Hamid Alinejad-Rokny , Arcot Sowmya , Imran Razzak

We propose a 3D convolutional neural network to simultaneously segment and detect cell nuclei in confocal microscopy images. Mirroring the co-dependency of these tasks, our proposed model consists of two serial components: the first part…

Image and Video Processing · Electrical Eng. & Systems 2018-09-07 Sundaresh Ram , Vicky T. Nguyen , Kirsten H. Limesand , Mert R. Sabuncu

Object segmentation and structure localization are important steps in automated image analysis pipelines for microscopy images. We present a convolution neural network (CNN) based deep learning architecture for segmentation of objects in…

Computer Vision and Pattern Recognition · Computer Science 2019-01-24 Shan E Ahmed Raza , Linda Cheung , Muhammad Shaban , Simon Graham , David Epstein , Stella Pelengaris , Michael Khan , Nasir M. Rajpoot

Most recent semantic segmentation methods train deep convolutional neural networks with fully annotated masks requiring pixel-accuracy for good quality training. Common weakly-supervised approaches generate full masks from partial input…

Computer Vision and Pattern Recognition · Computer Science 2018-04-05 Meng Tang , Abdelaziz Djelouah , Federico Perazzi , Yuri Boykov , Christopher Schroers

Image segmentation is a fundamental and challenging problem in computer vision with applications spanning multiple areas, such as medical imaging, remote sensing, and autonomous vehicles. Recently, convolutional neural networks (CNNs) have…

Computer Vision and Pattern Recognition · Computer Science 2020-06-24 Ali Hatamizadeh

Precise and accurate segmentation of the most common head-and-neck tumor, nasopharyngeal carcinoma (NPC), in MRI sheds light on treatment and regulatory decisions making. However, the large variations in the lesion size and shape of NPC,…

Image and Video Processing · Electrical Eng. & Systems 2020-12-22 Pin Tang , Chen Zu , Mei Hong , Rui Yan , Xingchen Peng , Jianghong Xiao , Xi Wu , Jiliu Zhou , Luping Zhou , Yan Wang

This paper presents a new regularization method to train a fully convolutional network for semantic tissue segmentation in histopathological images. This method relies on the benefit of unsupervised learning, in the form of image…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 C. T. Sari , C. Sokmensuer , C. Gunduz-Demir

Three-dimensional (3D) integrated renal structures (IRS) segmentation is important in clinical practice. With the advancement of deep learning techniques, many powerful frameworks focusing on medical image segmentation are proposed. In this…

Image and Video Processing · Electrical Eng. & Systems 2022-09-08 Kangqing Ye , Peng Liu , Xiaoyang Zou , Qin Zhou , Guoyan Zheng

Nuclei detection is an important task in the histology domain as it is a main step toward further analysis such as cell counting, cell segmentation, study of cell connections, etc. This is a challenging task due to the complex texture of…

Computer Vision and Pattern Recognition · Computer Science 2018-08-28 Navid Alemi Koohababni , Mostafa Jahanifar , Ali Gooya , Nasir Rajpoot

Segmentation of nuclei regions from histological images enables morphometric analysis of nuclei structures, which in turn helps in the detection and diagnosis of diseases under consideration. To develop a nuclei segmentation algorithm,…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Suman Mahapatra , Pradipta Maji

In the last decade, research on artificial intelligence has seen rapid growth with deep learning models, especially in the field of medical image segmentation. Various studies demonstrated that these models have powerful prediction…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Dominik Müller , Iñaki Soto-Rey , Frank Kramer

Lung cancer ranks as one of the leading causes of cancer diagnosis and is the foremost cause of cancer-related mortality worldwide. The early detection of lung nodules plays a pivotal role in improving outcomes for patients, as it enables…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Jiasen Zhang , Mingrui Yang , Weihong Guo , Brian A. Xavier , Michael Bolen , Xiaojuan Li

Lung cancer is one of the most deadly diseases in the world. Detecting such tumors at an early stage can be a tedious task. Existing deep learning architecture for lung nodule identification used complex architecture with large number of…

Image and Video Processing · Electrical Eng. & Systems 2020-09-25 Shah B. Shrey , Lukman Hakim , Muthusubash Kavitha , Hae Won Kim , Takio Kurita

Nuclei segmentation is a crucial task for whole slide image analysis in digital pathology. Generally, the segmentation performance of fully-supervised learning heavily depends on the amount and quality of the annotated data. However, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Yi Lin , Zhiyong Qu , Hao Chen , Zhongke Gao , Yuexiang Li , Lili Xia , Kai Ma , Yefeng Zheng , Kwang-Ting Cheng

Cell nuclei segmentation is one of the most important tasks in the analysis of biomedical images. With ever-growing sizes and amounts of three-dimensional images to be processed, there is a need for better and faster segmentation methods.…

Computer Vision and Pattern Recognition · Computer Science 2017-02-20 Julian Arz , Peter Sanders , Johannes Stegmaier , Ralf Mikut

This study addresses critical gaps in automated lymphoma segmentation from PET/CT images, focusing on issues often overlooked in existing literature. While deep learning has been applied for lymphoma lesion segmentation, few studies…

Segmentation of lymphoma lesions is challenging due to their varied sizes and locations in whole-body PET scans. This work presents a fully-automated segmentation technique using a multi-center dataset of diffuse large B-cell lymphoma…

Histology method is vital in the diagnosis and prognosis of cancers and many other diseases. For the analysis of histopathological images, we need to detect and segment all gland structures. These images are very challenging, and the task…

Image and Video Processing · Electrical Eng. & Systems 2019-11-05 Safiye Rezaei , Ali Emami , Nader Karimi , Shadrokh Samavi