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Steady state is an essential concept in reaction networks. Its stability reflects fundamental characteristics of several biological phenomena such as cellular signal transduction and gene expression. Because biochemical reactions occur at…

Molecular Networks · Quantitative Biology 2019-04-19 Tan Van Vu , Yoshihiko Hasegawa

Biochemical reaction networks in living cells usually involve reversible covalent modification of signaling molecules, such as protein phosphorylation. Under conditions of small molecule numbers, as is frequently the case in living cells,…

Molecular Networks · Quantitative Biology 2013-05-29 C. Metzner , M. Sajitz-Hermstein , M. Schmidberger , B. Fabry

In this paper, we introduce a family of processes with values on the nonnegative integers that describes the dynamics of populations where individuals are allowed to have different types of interactions. The types of interactions that we…

Probability · Mathematics 2020-03-31 Adrián González Casanova , Juan Carlos Pardo , José Luis Perez

Physical mechanisms of phase separation in living systems can play key physiological roles and have recently been the focus of intensive studies. The strongly heterogeneous and disordered nature of such phenomena in the biological domain…

Statistical Mechanics · Physics 2022-01-28 N. Lauber , O. Tichacek , R. Bose , C. Flamm , L. Leuzzi , T-Y Dora tang , K. Ruiz-Mirazo , D. De Martino

The biologically-inspired swarm paradigm is being used to design self-organizing systems of locally interacting artificial agents. A major difficulty in designing swarms with desired characteristics is understanding the causal relation…

Multiagent Systems · Computer Science 2016-11-17 Aram Galstyan , Tad Hogg , Kristina Lerman

Living cells encode and transmit information in the temporal dynamics of biochemical components. Gaining a detailed understanding of the input-output relationship in biological systems therefore requires quantitative measures that capture…

Molecular Networks · Quantitative Biology 2019-04-04 Lorenzo Duso , Christoph Zechner

We consider stochastic descriptions of chemical reaction networks in which there are both fast and slow reactions, and for which the time scales are widely separated. We develop a computational algorithm that produces the generator of the…

Dynamical Systems · Mathematics 2015-12-11 Xingye Kan , Chang Hyeong Lee , Hans G. Othmer

We discuss a method to describe the qualitative dynamics of chemical reaction networks in terms of symbolic dynamics. The method, that can be applied to mass-action reaction networks with separated timescales, uses solutions of the partial…

Molecular Networks · Quantitative Biology 2022-05-17 Aurélien Desoeuvres , Peter Szmolyan , Ovidiu Radulescu

The complexity of many biological, social and technological systems stems from the richness of the interactions among their units. Over the past decades, a great variety of complex systems has been successfully described as networks whose…

This paper is mainly devoted to lay an empirical foundation for further research on complex spatial dynamics of two-population interaction. Based on the US population census data, a rural and urban population interaction model is developed.…

Physics and Society · Physics 2016-06-14 Yanguang Chen , Feng Xu

In an experimental study of single enzyme reactions, it has been proposed that the rate constants of the enzymatic reactions fluctuate randomly, according to a given distribution. To quantify the uncertainty arising from random rate…

Quantitative Methods · Quantitative Biology 2012-02-07 Chia Ying Lee

This paper is concerned with classes of models of stochastic reaction dynamics with time-scales separation. We demonstrate that the existence of the time-scale separation naturally leads to the application of the averaging principle and…

Computational Physics · Physics 2007-05-23 Sergey Plyasunov

Main aim of this topical issue is to report recent advances in noisy nonequilibrium processes useful to describe the dynamics of ecological systems and to address the mechanisms of spatio-temporal pattern formation in ecology both from the…

Biological Physics · Physics 2009-11-13 Astero Provata , Igor M. Sokolov , Bernardo Spagnolo

Understanding the causes and effects of spatial aggregation is one of the most fundamental problems in ecology. Aggregation is an emergent phenomenon arising from the interactions between the individuals of the population, able to sense…

Populations and Evolution · Quantitative Biology 2015-06-05 Juan A. Bonachela , Miguel A. Munoz , Simon A. Levin

In-depth studies of sociotechnical systems are largely limited to single instances. Network surveys are expensive, and platforms vary in important ways, from interface design, to social norms, to historical contingencies. With single…

Social and Information Networks · Computer Science 2018-11-06 Abigail Z. Jacobs

Mathematical models of motility are often based on random-walk descriptions of discrete individuals that can move according to certain rules. It is usually the case that large masses concentrated in small regions of space have a great…

Physics and Society · Physics 2022-11-23 Carles Falcó

Patterns in complex systems store hidden information of the system which is needed to be explored. We present a simple model of cytokine and T-cells interaction and studied the model within stochastic framework by constructing Master…

Populations and Evolution · Quantitative Biology 2022-09-23 Moirangthem Shubhakanta Singh , Mairembam Kelvin Singh , R. K. Brojen Singh

In this paper, we investigate the asymptotic behavior of individual-based models describing the evolution of a population structured by a real trait, subject to selection and mutation. We consider two different sets of assumptions: first,…

Probability · Mathematics 2026-03-03 Anouar Jeddi

Mathematical models of spatial population dynamics typically focus on the interplay between dispersal events and birth/death processes. However, for many animal communities, significant arrangement in space can occur on shorter timescales,…

Populations and Evolution · Quantitative Biology 2019-06-06 Jonathan R. Potts , Mark A. Lewis

Probabilistic inference provides a language for describing how organisms may learn from and adapt to their environment. The computations needed to implement probabilistic inference often require specific representations, akin to having the…

Molecular Networks · Quantitative Biology 2018-06-28 Yarden Katz , Michael Springer , Walter Fontana
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