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Scientific Large Language Models (Sci-LLMs) have emerged as a promising frontier for accelerating biological discovery. However, these models face a fundamental challenge when processing raw biomolecular sequences: the tokenization dilemma.…

The development of chemical engineering technology is a multi-stage process that encompasses laboratory research, scaling up, and industrial deployment. This process demands interdisciplinary col laboration and typically incurs significant…

Chemical Physics · Physics 2025-09-10 Heng Zhang , Jibin Zhou , Feiyang Xu , Jian Cui , Yi Li , Fan Yang , Hao Wang , Xin Li , Mao Ye

One major problem in Natural Language Processing is the automatic analysis and representation of human language. Human language is ambiguous and deeper understanding of semantics and creating human-to-machine interaction have required an…

Computation and Language · Computer Science 2022-06-01 Neslihan Suzen , Alexander N. Gorban , Jeremy Levesley , Evgeny M. Mirkes

The field of Text-to-Speech has experienced huge improvements last years benefiting from deep learning techniques. Producing realistic speech becomes possible now. As a consequence, the research on the control of the expressiveness,…

Computation and Language · Computer Science 2019-03-28 Noé Tits , Fengna Wang , Kevin El Haddad , Vincent Pagel , Thierry Dutoit

Developing complex biomolecular workflows is not always straightforward. It requires tedious developments to enable the interoperability between the different biomolecular simulation and analysis tools. Moreover, the need to execute the…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-12-20 Jorge Ejarque , Pau Andrio , Adam Hospital , Javier Conejero , Daniele Lezzi , Josep LL. Gelpi , Rosa M. Badia

The article suggests a description of a system of tables with a set of special lists absorbing a semantics of data and reflects a fullness of data. It shows how their parallel processing can be constructed based on the descriptions. The…

Distributed, Parallel, and Cluster Computing · Computer Science 2008-11-03 R. Nuriyev

The integration of Large Language Models (LLMs) into biomedical research offers new opportunities for domainspecific reasoning and knowledge representation. However, their performance depends heavily on the semantic quality of training…

We introduce a family of deep-learning architectures for inter-sentence relation extraction, i.e., relations where the participants are not necessarily in the same sentence. We apply these architectures to an important use case in the…

Computation and Language · Computer Science 2021-12-20 Enrique Noriega-Atala , Peter M. Lovett , Clayton T. Morrison , Mihai Surdeanu

The general capabilities of Large Language Models (LLM) highly rely on the composition and selection on extensive pretraining datasets, treated as commercial secrets by several institutions. To mitigate this issue, we open-source the…

With the need to produce ever larger and more complex software systems, the use of reusable components has become increasingly imperative. Of the many existing and proposed techniques for software development, it seems clear that…

Software Engineering · Computer Science 2015-08-26 Luiz Fernando Capretz

While the uptake of data-driven approaches for materials science and chemistry is at an exciting, early stage, to realise the true potential of machine learning models for successful scientific discovery, they must have qualities beyond…

Materials Science · Physics 2022-06-28 Felipe Oviedo , Juan Lavista Ferres , Tonio Buonassisi , Keith Butler

Segmentation remains an important preprocessing step both in languages where "words" or other important syntactic/semantic units (like morphemes) are not clearly delineated by white space, as well as when dealing with continuous speech…

Computation and Language · Computer Science 2021-09-07 C. M. Downey , Fei Xia , Gina-Anne Levow , Shane Steinert-Threlkeld

Recent advances in biochemical computing, i.e., information processing with cascades of primarily enzymatic reactions realizing computing gates, such as AND, OR, etc., as well as progress in networking these gates and coupling of the…

Biological Physics · Physics 2010-10-12 Vladimir Privman , Evgeny Katz , Joseph Wang

Component-based software engineering (CBSE) decomposes complex systems into reusable components. Model-driven engineering (MDE) aims to abstract from complexities by lifting abstract models to primary development artifacts. Component and…

Software Engineering · Computer Science 2015-11-02 Lars Hermerschmidt , Katrin Hölldobler , Bernhard Rumpe , Andreas Wortmann

Finite chase, or alternatively chase termination, is an important condition to ensure the decidability of existential rule languages. In the past few years, a number of rule languages with finite chase have been studied. In this work, we…

Artificial Intelligence · Computer Science 2015-01-12 Heng Zhang , Yan Zhang , Jia-Huai You

Algebraic specification has a long tradition in bridging the gap between specification and programming by making specifications executable. Building on extensive experience in designing, implementing and using specification formalisms that…

Programming Languages · Computer Science 2011-07-04 Jeroen van den Bos , Mark Hills , Paul Klint , Tijs van der Storm , Jurgen J. Vinju

Logic of Behaviour in Context (LBC) is a spatio-temporal logic for expressing properties of continuous-state processes, such as biochemical reaction networks. LBC builds on the existing Metric Interval Temporal Logic (MITL) and adds a…

Logic in Computer Science · Computer Science 2017-02-13 Christopher J. Banks , Ian Stark

Language modeling has seen impressive progress over the last years, mainly prompted by the invention of the Transformer architecture, sparking a revolution in many fields of machine learning, with breakthroughs in chemistry and biology. In…

Machine Learning · Computer Science 2023-10-11 Andres M Bran , Philippe Schwaller

Bayesian probabilistic programming languages (BPPLs) let users denote statistical models as code while the interpreter infers the posterior distribution. The semantics of BPPLs are usually mathematically complex and unable to reason about…

Programming Languages · Computer Science 2025-12-03 Shing Hin Ho , Nicolas Wu , Azalea Raad